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122 related items for PubMed ID: 12530651

  • 1. Differences in substrate and inhibitor kinetics of human type 1 and type 2 3beta-hydroxysteroid dehydrogenase are explained by the type 1 mutant, H156Y.
    Thomas JL, Mason JI, Brandt S, Norris W.
    Endocr Res; 2002 Nov; 28(4):471-5. PubMed ID: 12530651
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  • 2. Structure/function relationships responsible for the kinetic differences between human type 1 and type 2 3beta-hydroxysteroid dehydrogenase and for the catalysis of the type 1 activity.
    Thomas JL, Mason JI, Brandt S, Spencer BR, Norris W.
    J Biol Chem; 2002 Nov 08; 277(45):42795-801. PubMed ID: 12205101
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  • 3. Site-directed mutagenesis identifies amino acid residues associated with the dehydrogenase and isomerase activities of human type I (placental) 3beta-hydroxysteroid dehydrogenase/isomerase.
    Thomas JL, Evans BW, Blanco G, Mercer RW, Mason JI, Adler S, Nash WE, Isenberg KE, Strickler RC.
    J Steroid Biochem Mol Biol; 1998 Sep 08; 66(5-6):327-34. PubMed ID: 9749838
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  • 5. Induction of 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase type 1 gene transcription in human breast cancer cell lines and in normal mammary epithelial cells by interleukin-4 and interleukin-13.
    Gingras S, Moriggl R, Groner B, Simard J.
    Mol Endocrinol; 1999 Jan 08; 13(1):66-81. PubMed ID: 9892013
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  • 6. Creation of a fully active, cytosolic form of human type I 3beta-hydroxysteroid dehydrogenase/isomerase by the deletion of a membrane-spanning domain.
    Thomas JL, Evans BW, Blanco G, Mason JI, Strickler RC.
    J Mol Endocrinol; 1999 Oct 08; 23(2):231-9. PubMed ID: 10514560
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  • 7. Activity and inhibition of 3-beta-hydroxysteroid dehydrogenase/delta-5-4-isomerase in human skin.
    Tóth I, Szécsi M, Julesz J, Faredin I.
    Skin Pharmacol; 1997 Oct 08; 10(3):160-8. PubMed ID: 9287397
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  • 8. Bovine adrenal 3beta-hydroxysteroid dehydrogenase (E.C. 1.1.1. 145)/5-ene-4-ene isomerase (E.C. 5.3.3.1): characterization and its inhibition by isoflavones.
    Wong CK, Keung WM.
    J Steroid Biochem Mol Biol; 1999 Dec 31; 71(5-6):191-202. PubMed ID: 10704908
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  • 9. 3 beta-hydroxysteroid dehydrogenase isomerase (3beta-HSD) activity in the rat sciatic nerve: kinetic analysis and regulation by steroids.
    Coirini H, Gouézou M, Delespierre B, Schumacher M, Guennoun R.
    J Steroid Biochem Mol Biol; 2003 May 31; 85(1):89-94. PubMed ID: 12798361
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  • 10. Molecular biology of the 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase gene family.
    Simard J, Ricketts ML, Gingras S, Soucy P, Feltus FA, Melner MH.
    Endocr Rev; 2005 Jun 31; 26(4):525-82. PubMed ID: 15632317
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  • 11. Characterization of the structure-activity relationships of rat types I and II 3 beta-hydroxysteroid dehydrogenase/delta 5 -delta 4 isomerase by site-directed mutagenesis and expression in HeLa cells.
    Simard J, de Launoit Y, Labrie F.
    J Biol Chem; 1991 Aug 15; 266(23):14842-5. PubMed ID: 1831194
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  • 12. Human placental 3β-hydroxysteroid dehydrogenase/steroid Δ5,4-isomerase 1: Identity, regulation and environmental inhibitors.
    Zhu Q, Pan P, Chen X, Wang Y, Zhang S, Mo J, Li X, Ge RS.
    Toxicology; 2019 Sep 01; 425():152253. PubMed ID: 31351905
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  • 16. Enzyme characteristics of two distinct forms of mouse 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase complementary deoxyribonucleic acids expressed in COS-1 cells.
    Clarke TR, Bain PA, Sha L, Payne AH.
    Endocrinology; 1993 May 01; 132(5):1971-6. PubMed ID: 8477648
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  • 17. Affinity radiolabeling identifies peptides associated with the isomerase activity of human type I (placental) 3beta-hydroxysteroid dehydrogenase/isomerase.
    Thomas JL, Evans BW, Strickler RC.
    Biochemistry; 1997 Jul 22; 36(29):9029-34. PubMed ID: 9220991
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  • 18. Characterization of the guinea pig 3beta-hydroxysteroid dehydrogenase/Delta5-Delta4-isomerase expressed in the adrenal gland and gonads.
    Durocher F, Sanchez R, Ricketts ML, Labrie Y, Laudet V, Simard J.
    J Steroid Biochem Mol Biol; 2005 Nov 22; 97(3):289-98. PubMed ID: 16143518
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  • 19. Structure-function relationships and molecular genetics of the 3 beta-hydroxysteroid dehydrogenase gene family.
    Simard J, Sanchez R, Durocher F, Rhéaume E, Turgeon C, Labrie Y, Luu-The V, Mebarki F, Morel Y, de Launoit Y.
    J Steroid Biochem Mol Biol; 1995 Dec 22; 55(5-6):489-505. PubMed ID: 8547174
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  • 20. The higher affinity of human type 1 3beta-hydroxysteroid dehydrogenase (3beta-HSD1) for substrate and inhibitor steroids relative to human 3beta-HSD2 is validated in MCF-7 tumor cells and related to subunit interactions.
    Thomas JL, Umland TC, Scaccia LA, Boswell EL, Kacsoh B.
    Endocr Res; 2004 Nov 22; 30(4):935-41. PubMed ID: 15666848
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