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Journal Abstract Search

197 related items for PubMed ID: 12532376

  • 1. Effects of types of sugar on the stabilization of protein in the dried state.
    Imamura K, Ogawa T, Sakiyama T, Nakanishi K.
    J Pharm Sci; 2003 Feb; 92(2):266-74. PubMed ID: 12532376
    [Abstract] [Full Text] [Related]

  • 2. Improving the physical stability of freeze-dried amorphous sugar matrices by compression at several hundreds MPa.
    Kagotani R, Kinugawa K, Nomura M, Imanaka H, Ishida N, Imamura K.
    J Pharm Sci; 2013 Jul; 102(7):2187-97. PubMed ID: 23625861
    [Abstract] [Full Text] [Related]

  • 3. Mechanism of protein stabilization by sugars during freeze-drying and storage: native structure preservation, specific interaction, and/or immobilization in a glassy matrix?
    Chang L, Shepherd D, Sun J, Ouellette D, Grant KL, Tang XC, Pikal MJ.
    J Pharm Sci; 2005 Jul; 94(7):1427-44. PubMed ID: 15920775
    [Abstract] [Full Text] [Related]

  • 4. Evaluation of hydration states of protein in freeze-dried amorphous sugar matrix.
    Imamura K, Iwai M, Ogawa T, Sakiyama T, Nakanishi K.
    J Pharm Sci; 2001 Dec; 90(12):1955-63. PubMed ID: 11745754
    [Abstract] [Full Text] [Related]

  • 5. Characterization of carbohydrate-protein matrices for nutrient delivery.
    Zhou Y, Roos YH.
    J Food Sci; 2011 May; 76(4):E368-76. PubMed ID: 22417357
    [Abstract] [Full Text] [Related]

  • 6. Physicochemical stability of crystalline sugars and their spray-dried forms: dependence upon relative humidity and suitability for use in powder inhalers.
    Naini V, Byron PR, Phillips EM.
    Drug Dev Ind Pharm; 1998 Oct; 24(10):895-909. PubMed ID: 9876544
    [Abstract] [Full Text] [Related]

  • 7. Influence of compression on water sorption, glass transition, and enthalpy relaxation behavior of freeze-dried amorphous sugar matrices.
    Imamura K, Kagotani R, Nomura M, Tanaka K, Kinugawa K, Nakanishi K.
    Int J Pharm; 2011 Apr 15; 408(1-2):76-83. PubMed ID: 21291973
    [Abstract] [Full Text] [Related]

  • 8. Characteristics of hydrogen bond formation between sugar and polymer in freeze-dried mixtures under different rehumidification conditions and its impact on the glass transition temperature.
    Imamura K, Asano Y, Maruyama Y, Yokoyama T, Nomura M, Ogawa S, Nakanishi K.
    J Pharm Sci; 2008 Mar 15; 97(3):1301-12. PubMed ID: 17683061
    [Abstract] [Full Text] [Related]

  • 9. The impact of drying method and formulation on the physical properties and stability of methionyl human growth hormone in the amorphous solid state.
    Abdul-Fattah AM, Lechuga-Ballesteros D, Kalonia DS, Pikal MJ.
    J Pharm Sci; 2008 Jan 15; 97(1):163-84. PubMed ID: 17722086
    [Abstract] [Full Text] [Related]

  • 10. Stability of α-tocopherol in freeze-dried sugar-protein-oil emulsion solids as affected by water plasticization and sugar crystallization.
    Zhou Y, Roos YH.
    J Agric Food Chem; 2012 Aug 01; 60(30):7497-505. PubMed ID: 22793794
    [Abstract] [Full Text] [Related]

  • 11. Size and molecular flexibility of sugars determine the storage stability of freeze-dried proteins.
    Tonnis WF, Mensink MA, de Jager A, van der Voort Maarschalk K, Frijlink HW, Hinrichs WL.
    Mol Pharm; 2015 Mar 02; 12(3):684-94. PubMed ID: 25581526
    [Abstract] [Full Text] [Related]

  • 12. Stable sugar-based protein formulations by supercritical fluid drying.
    Jovanović N, Bouchard A, Sutter M, Van Speybroeck M, Hofland GW, Witkamp GJ, Crommelin DJ, Jiskoot W.
    Int J Pharm; 2008 Jan 04; 346(1-2):102-8. PubMed ID: 17659851
    [Abstract] [Full Text] [Related]

  • 13. Water sorption and glass transition behaviors of freeze-dried sucrose-dextran mixtures.
    Imamura K, Fukushima A, Sakaura K, Sugita T, Sakiyama T, Nakanishi K.
    J Pharm Sci; 2002 Oct 04; 91(10):2175-81. PubMed ID: 12226844
    [Abstract] [Full Text] [Related]

  • 14. Distinct effects of sucrose and trehalose on protein stability during supercritical fluid drying and freeze-drying.
    Jovanović N, Bouchard A, Hofland GW, Witkamp GJ, Crommelin DJ, Jiskoot W.
    Eur J Pharm Sci; 2006 Mar 04; 27(4):336-45. PubMed ID: 16338123
    [Abstract] [Full Text] [Related]

  • 15. Effect of γ-cyclodextrin as a lyoprotectant for freeze-dried actinidin.
    Furuishi T, Ishigami T, Endo T, Nagase H, Okada M, Nishiyama I, Jo A, Terao K, Ueda H.
    Pharmazie; 2015 May 04; 70(5):296-9. PubMed ID: 26062296
    [Abstract] [Full Text] [Related]

  • 16. Effect of vacuum drying on protein-mannitol interactions: the physical state of mannitol and protein structure in the dried state.
    Sharma VK, Kalonia DS.
    AAPS PharmSciTech; 2004 Feb 17; 5(1):E10. PubMed ID: 15198531
    [Abstract] [Full Text] [Related]

  • 17. Temperature scanning FTIR analysis of interactions between sugar and polymer additive in amorphous sugar-polymer mixtures.
    Imamura K, Ohyama K, Yokoyama T, Maruyama Y, Imanaka H, Nakanishi K.
    J Pharm Sci; 2008 Jan 17; 97(1):519-28. PubMed ID: 17724665
    [Abstract] [Full Text] [Related]

  • 18. Effects of sodium tetraborate and boric acid on nonisothermal mannitol crystallization in frozen solutions and freeze-dried solids.
    Izutsu K, Ocheda SO, Aoyagi N, Kojima S.
    Int J Pharm; 2004 Apr 01; 273(1-2):85-93. PubMed ID: 15010133
    [Abstract] [Full Text] [Related]

  • 19. Effects of sugar additives on protein stability of recombinant human serum albumin during lyophilization and storage.
    Han Y, Jin BS, Lee SB, Sohn Y, Joung JW, Lee JH.
    Arch Pharm Res; 2007 Sep 01; 30(9):1124-31. PubMed ID: 17958330
    [Abstract] [Full Text] [Related]

  • 20. Drying-induced variations in physico-chemical properties of amorphous pharmaceuticals and their impact on stability (I): stability of a monoclonal antibody.
    Abdul-Fattah AM, Truong-Le V, Yee L, Nguyen L, Kalonia DS, Cicerone MT, Pikal MJ.
    J Pharm Sci; 2007 Aug 01; 96(8):1983-2008. PubMed ID: 17286290
    [Abstract] [Full Text] [Related]

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