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237 related items for PubMed ID: 12532409

  • 1. PDAPP; YFP double transgenic mice: a tool to study amyloid-beta associated changes in axonal, dendritic, and synaptic structures.
    Brendza RP, O'Brien C, Simmons K, McKeel DW, Bales KR, Paul SM, Olney JW, Sanes JR, Holtzman DM.
    J Comp Neurol; 2003 Feb 17; 456(4):375-83. PubMed ID: 12532409
    [Abstract] [Full Text] [Related]

  • 2. Cholinergic neuropathology in a mouse model of Alzheimer's disease.
    German DC, Yazdani U, Speciale SG, Pasbakhsh P, Games D, Liang CL.
    J Comp Neurol; 2003 Aug 04; 462(4):371-81. PubMed ID: 12811807
    [Abstract] [Full Text] [Related]

  • 3. Use of YFP to study amyloid-beta associated neurite alterations in live brain slices.
    Brendza RP, Simmons K, Bales KR, Paul SM, Goldberg MP, Holtzman DM.
    Neurobiol Aging; 2003 Dec 04; 24(8):1071-7. PubMed ID: 14643378
    [Abstract] [Full Text] [Related]

  • 4. Phosphorylated tau in neuritic plaques of APP(sw)/Tau (vlw) transgenic mice and Alzheimer disease.
    Pérez M, Morán MA, Ferrer I, Avila J, Gómez-Ramos P.
    Acta Neuropathol; 2008 Oct 04; 116(4):409-18. PubMed ID: 18679696
    [Abstract] [Full Text] [Related]

  • 5. Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse.
    Gordon MN, Holcomb LA, Jantzen PT, DiCarlo G, Wilcock D, Boyett KW, Connor K, Melachrino J, O'Callaghan JP, Morgan D.
    Exp Neurol; 2002 Feb 04; 173(2):183-95. PubMed ID: 11822882
    [Abstract] [Full Text] [Related]

  • 6. Anti-Abeta antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice.
    Brendza RP, Bacskai BJ, Cirrito JR, Simmons KA, Skoch JM, Klunk WE, Mathis CA, Bales KR, Paul SM, Hyman BT, Holtzman DM.
    J Clin Invest; 2005 Feb 04; 115(2):428-33. PubMed ID: 15668737
    [Abstract] [Full Text] [Related]

  • 7. Transgenic mice overexpressing amyloid beta protein are an incomplete model of Alzheimer disease.
    Schwab C, Hosokawa M, McGeer PL.
    Exp Neurol; 2004 Jul 04; 188(1):52-64. PubMed ID: 15191802
    [Abstract] [Full Text] [Related]

  • 8. Various dendritic abnormalities are associated with fibrillar amyloid deposits in Alzheimer's disease.
    Grutzendler J, Helmin K, Tsai J, Gan WB.
    Ann N Y Acad Sci; 2007 Feb 04; 1097():30-9. PubMed ID: 17413007
    [Abstract] [Full Text] [Related]

  • 9. Amyloid precursor protein cytoplasmic domain with phospho-Thr668 accumulates in Alzheimer's disease and its transgenic models: a role to mediate interaction of Abeta and tau.
    Shin RW, Ogino K, Shimabuku A, Taki T, Nakashima H, Ishihara T, Kitamoto T.
    Acta Neuropathol; 2007 Jun 04; 113(6):627-36. PubMed ID: 17431643
    [Abstract] [Full Text] [Related]

  • 10. Amyloid deposits show complexity and intimate spatial relationship with dendrosomatic plasma membranes: an electron microscopic 3D reconstruction analysis in 3xTg-AD mice and aged canines.
    Nuntagij P, Oddo S, LaFerla FM, Kotchabhakdi N, Ottersen OP, Torp R.
    J Alzheimers Dis; 2009 Jun 04; 16(2):315-23. PubMed ID: 19221421
    [Abstract] [Full Text] [Related]

  • 11. High sensitivity analysis of amyloid-beta peptide composition in amyloid deposits from human and PS2APP mouse brain.
    Güntert A, Döbeli H, Bohrmann B.
    Neuroscience; 2006 Dec 01; 143(2):461-75. PubMed ID: 17008022
    [Abstract] [Full Text] [Related]

  • 12. Amyloid cored plaques in Tg2576 transgenic mice are characterized by giant plaques, slightly activated microglia, and the lack of paired helical filament-typed, dystrophic neurites.
    Sasaki A, Shoji M, Harigaya Y, Kawarabayashi T, Ikeda M, Naito M, Matsubara E, Abe K, Nakazato Y.
    Virchows Arch; 2002 Oct 01; 441(4):358-67. PubMed ID: 12404061
    [Abstract] [Full Text] [Related]

  • 13. Transplanted astrocytes internalize deposited beta-amyloid peptides in a transgenic mouse model of Alzheimer's disease.
    Pihlaja R, Koistinaho J, Malm T, Sikkilä H, Vainio S, Koistinaho M.
    Glia; 2008 Jan 15; 56(2):154-63. PubMed ID: 18004725
    [Abstract] [Full Text] [Related]

  • 14. Exclusive association and simultaneous appearance of congophilic plaques and AT8-positive dystrophic neurites in Tg2576 mice suggest a mechanism of senile plaque formation and progression of neuritic dystrophy in Alzheimer's disease.
    Noda-Saita K, Terai K, Iwai A, Tsukamoto M, Shitaka Y, Kawabata S, Okada M, Yamaguchi T.
    Acta Neuropathol; 2004 Nov 15; 108(5):435-42. PubMed ID: 15372280
    [Abstract] [Full Text] [Related]

  • 15. Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model.
    Holtzman DM, Fagan AM, Mackey B, Tenkova T, Sartorius L, Paul SM, Bales K, Ashe KH, Irizarry MC, Hyman BT.
    Ann Neurol; 2000 Jun 15; 47(6):739-47. PubMed ID: 10852539
    [Abstract] [Full Text] [Related]

  • 16. Amyloid deposition in APP23 mice is associated with the expression of cyclins in astrocytes but not in neurons.
    Gärtner U, Brückner MK, Krug S, Schmetsdorf S, Staufenbiel M, Arendt T.
    Acta Neuropathol; 2003 Dec 15; 106(6):535-44. PubMed ID: 12923647
    [Abstract] [Full Text] [Related]

  • 17. Enhanced susceptibility of S-100B transgenic mice to neuroinflammation and neuronal dysfunction induced by intracerebroventricular infusion of human beta-amyloid.
    Craft JM, Watterson DM, Marks A, Van Eldik LJ.
    Glia; 2005 Aug 15; 51(3):209-16. PubMed ID: 15810011
    [Abstract] [Full Text] [Related]

  • 18. Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein.
    Games D, Adams D, Alessandrini R, Barbour R, Berthelette P, Blackwell C, Carr T, Clemens J, Donaldson T, Gillespie F.
    Nature; 1995 Feb 09; 373(6514):523-7. PubMed ID: 7845465
    [Abstract] [Full Text] [Related]

  • 19. Deposition of mouse amyloid beta in human APP/PS1 double and single AD model transgenic mice.
    van Groen T, Kiliaan AJ, Kadish I.
    Neurobiol Dis; 2006 Sep 09; 23(3):653-62. PubMed ID: 16829076
    [Abstract] [Full Text] [Related]

  • 20. Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?
    Götz J, Ittner LM, Kins S.
    J Neurochem; 2006 Aug 09; 98(4):993-1006. PubMed ID: 16787410
    [Abstract] [Full Text] [Related]


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