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Journal Abstract Search

1038 related items for PubMed ID: 12538494

  • 1. Examination of the antiproliferative activity of iron chelators: multiple cellular targets and the different mechanism of action of triapine compared with desferrioxamine and the potent pyridoxal isonicotinoyl hydrazone analogue 311.
    Chaston TB, Lovejoy DB, Watts RN, Richardson DR.
    Clin Cancer Res; 2003 Jan; 9(1):402-14. PubMed ID: 12538494
    [Abstract] [Full Text] [Related]

  • 2. The effect of the iron(III) chelator, desferrioxamine, on iron and transferrin uptake by the human malignant melanoma cell.
    Richardson D, Ponka P, Baker E.
    Cancer Res; 1994 Feb 01; 54(3):685-9. PubMed ID: 8306330
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  • 3. Inhibition of malignant cell growth by 311, a novel iron chelator of the pyridoxal isonicotinoyl hydrazone class: effect on the R2 subunit of ribonucleotide reductase.
    Green DA, Antholine WE, Wong SJ, Richardson DR, Chitambar CR.
    Clin Cancer Res; 2001 Nov 01; 7(11):3574-9. PubMed ID: 11705879
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  • 4. The iron metabolism of the human neuroblastoma cell: lack of relationship between the efficacy of iron chelation and the inhibition of DNA synthesis.
    Richardson DR, Ponka P.
    J Lab Clin Med; 1994 Nov 01; 124(5):660-71. PubMed ID: 7964124
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  • 5. Identification and characterization of thiosemicarbazones with antifungal and antitumor effects: cellular iron chelation mediating cytotoxic activity.
    Opletalová V, Kalinowski DS, Vejsová M, Kunes J, Pour M, Jampílek J, Buchta V, Richardson DR.
    Chem Res Toxicol; 2008 Sep 01; 21(9):1878-89. PubMed ID: 18698850
    [Abstract] [Full Text] [Related]

  • 6. Potent iron chelators increase the mRNA levels of the universal cyclin-dependent kinase inhibitor p21(CIP1/WAF1), but paradoxically inhibit its translation: a potential mechanism of cell cycle dysregulation.
    Le NT, Richardson DR.
    Carcinogenesis; 2003 Jun 01; 24(6):1045-58. PubMed ID: 12807743
    [Abstract] [Full Text] [Related]

  • 7. The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents III: the effect of the ligands on molecular targets involved in proliferation.
    Darnell G, Richardson DR.
    Blood; 1999 Jul 15; 94(2):781-92. PubMed ID: 10397746
    [Abstract] [Full Text] [Related]

  • 8. Potent antitumor activity of novel iron chelators derived from di-2-pyridylketone isonicotinoyl hydrazone involves fenton-derived free radical generation.
    Chaston TB, Watts RN, Yuan J, Richardson DR.
    Clin Cancer Res; 2004 Nov 01; 10(21):7365-74. PubMed ID: 15534113
    [Abstract] [Full Text] [Related]

  • 9. The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents.
    Richardson DR, Tran EH, Ponka P.
    Blood; 1995 Dec 01; 86(11):4295-306. PubMed ID: 7492790
    [Abstract] [Full Text] [Related]

  • 10. The effect of an iron (III) chelator, silybin, on the proliferation and cell cycle of Jurkat cells: a comparison with desferrioxamine.
    Gharagozloo M, Khoshdel Z, Amirghofran Z.
    Eur J Pharmacol; 2008 Jul 28; 589(1-3):1-7. PubMed ID: 18619590
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  • 13. Chelators at the cancer coalface: desferrioxamine to Triapine and beyond.
    Yu Y, Wong J, Lovejoy DB, Kalinowski DS, Richardson DR.
    Clin Cancer Res; 2006 Dec 01; 12(23):6876-83. PubMed ID: 17145804
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  • 16. Design, synthesis, and characterization of novel iron chelators: structure-activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3-nitrobenzoyl analogues as potent antitumor agents.
    Kalinowski DS, Yu Y, Sharpe PC, Islam M, Liao YT, Lovejoy DB, Kumar N, Bernhardt PV, Richardson DR.
    J Med Chem; 2007 Jul 26; 50(15):3716-29. PubMed ID: 17602603
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  • 19. Iron chelators deferoxamine and diethylenetriamine pentaacetic acid induce apoptosis in ovarian carcinoma.
    Brard L, Granai CO, Swamy N.
    Gynecol Oncol; 2006 Jan 26; 100(1):116-27. PubMed ID: 16203029
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  • 20. Development of novel aroylhydrazone ligands for iron chelation therapy: 2-pyridylcarboxaldehyde isonicotinoyl hydrazone analogs.
    Becker E, Richardson DR.
    J Lab Clin Med; 1999 Nov 26; 134(5):510-21. PubMed ID: 10560945
    [Abstract] [Full Text] [Related]

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