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151 related items for PubMed ID: 12538613

  • 1. The severe form of hypertension caused by the activating S810L mutation in the mineralocorticoid receptor is cortisone related.
    Rafestin-Oblin ME, Souque A, Bocchi B, Pinon G, Fagart J, Vandewalle A.
    Endocrinology; 2003 Feb; 144(2):528-33. PubMed ID: 12538613
    [Abstract] [Full Text] [Related]

  • 2. Identification of steroid ligands able to inactivate the mineralocorticoid receptor harboring the S810L mutation responsible for a severe form of hypertension.
    Pinon GM, Fagart J, Souque A, Auzou G, Vandewalle A, Rafestin-Oblin ME.
    Mol Cell Endocrinol; 2004 Mar 31; 217(1-2):181-8. PubMed ID: 15134816
    [Abstract] [Full Text] [Related]

  • 3. Activating mineralocorticoid receptor mutation in hypertension exacerbated by pregnancy.
    Geller DS, Farhi A, Pinkerton N, Fradley M, Moritz M, Spitzer A, Meinke G, Tsai FT, Sigler PB, Lifton RP.
    Science; 2000 Jul 07; 289(5476):119-23. PubMed ID: 10884226
    [Abstract] [Full Text] [Related]

  • 4. Evolution of hormone selectivity in glucocorticoid and mineralocorticoid receptors.
    Baker ME, Funder JW, Kattoula SR.
    J Steroid Biochem Mol Biol; 2013 Sep 07; 137():57-70. PubMed ID: 23907018
    [Abstract] [Full Text] [Related]

  • 5. The role of 11β-hydroxysteroid dehydrogenase type 2 in human hypertension.
    Ferrari P.
    Biochim Biophys Acta; 2010 Dec 07; 1802(12):1178-87. PubMed ID: 19909806
    [Abstract] [Full Text] [Related]

  • 6. The ligand-dependent interaction of mineralocorticoid receptor with coactivator and corepressor peptides suggests multiple activation mechanisms.
    Hultman ML, Krasnoperova NV, Li S, Du S, Xia C, Dietz JD, Lala DS, Welsch DJ, Hu X.
    Mol Endocrinol; 2005 Jun 07; 19(6):1460-73. PubMed ID: 15761029
    [Abstract] [Full Text] [Related]

  • 7. Crystal structure of a mutant mineralocorticoid receptor responsible for hypertension.
    Fagart J, Huyet J, Pinon GM, Rochel M, Mayer C, Rafestin-Oblin ME.
    Nat Struct Mol Biol; 2005 Jun 07; 12(6):554-5. PubMed ID: 15908963
    [Abstract] [Full Text] [Related]

  • 8. LLC-PK1 cells model 11 beta-hydroxysteroid dehydrogenase type 2 regulation of glucocorticoid access to renal mineralocorticoid receptors.
    Leckie C, Chapman KE, Edwards CR, Seckl JR.
    Endocrinology; 1995 Dec 07; 136(12):5561-9. PubMed ID: 7588309
    [Abstract] [Full Text] [Related]

  • 9. A mutation in the cofactor-binding domain of 11beta-hydroxysteroid dehydrogenase type 2 associated with mineralocorticoid hypertension.
    Odermatt A, Dick B, Arnold P, Zaehner T, Plueschke V, Deregibus MN, Repetto H, Frey BM, Frey FJ, Ferrari P.
    J Clin Endocrinol Metab; 2001 Mar 07; 86(3):1247-52. PubMed ID: 11238516
    [Abstract] [Full Text] [Related]

  • 10. An in Vitro triple screen model for human mineralocorticoid receptor activity.
    Liu H, Konzen S, Coy A, Rege J, Gomez-Sanchez CE, Rainey WE, Turcu AF.
    J Steroid Biochem Mol Biol; 2024 Oct 07; 243():106568. PubMed ID: 38866188
    [Abstract] [Full Text] [Related]

  • 11. Analysis of the S810L point mutation of the mineralocorticoid receptor in patients with pregnancy-induced hypertension.
    Schmider-Ross A, Wirsing M, Büscher U, Neitzel H, Krause M, Henrich W, Reles A, Dudenhausen JW.
    Hypertens Pregnancy; 2004 Oct 07; 23(1):113-9. PubMed ID: 15117605
    [Abstract] [Full Text] [Related]

  • 12. Stimulation of testosterone production in rat Leydig cells by aldosterone is mineralocorticoid receptor mediated.
    Ge RS, Dong Q, Sottas CM, Latif SA, Morris DJ, Hardy MP.
    Mol Cell Endocrinol; 2005 Nov 24; 243(1-2):35-42. PubMed ID: 16188378
    [Abstract] [Full Text] [Related]

  • 13. [Genetic disorders caused by gain or loss of function of the mineralocorticoid receptor].
    Arai K, Shibasaki T.
    Nihon Rinsho; 2002 Feb 24; 60(2):361-6. PubMed ID: 11857927
    [Abstract] [Full Text] [Related]

  • 14. Mineralocorticoid versus glucocorticoid receptor occupancy mediating aldosterone-stimulated sodium transport in a novel renal cell line.
    Gaeggeler HP, Gonzalez-Rodriguez E, Jaeger NF, Loffing-Cueni D, Norregaard R, Loffing J, Horisberger JD, Rossier BC.
    J Am Soc Nephrol; 2005 Apr 24; 16(4):878-91. PubMed ID: 15743993
    [Abstract] [Full Text] [Related]

  • 15. Translational research goes both ways: lessons from clinical studies.
    Funder JW.
    Clin Exp Pharmacol Physiol; 2008 Apr 24; 35(4):526-9. PubMed ID: 18307755
    [Abstract] [Full Text] [Related]

  • 16. A novel missense mutation, F826Y, in the mineralocorticoid receptor gene in Japanese hypertensives: its implications for clinical phenotypes.
    Kamide K, Yang J, Kokubo Y, Takiuchi S, Miwa Y, Horio T, Tanaka C, Banno M, Nagura J, Okayama A, Tomoike H, Kawano Y, Miyata T.
    Hypertens Res; 2005 Sep 24; 28(9):703-9. PubMed ID: 16419642
    [Abstract] [Full Text] [Related]

  • 17. 19-nor analogs of adrenal steroids: mineralocorticoid and glucocorticoid receptor activity.
    Wynne KN, Mercer J, Stockigt JR, Funder JW.
    Endocrinology; 1980 Nov 24; 107(5):1278-80. PubMed ID: 6253261
    [Abstract] [Full Text] [Related]

  • 18. Binding characteristics of mineralocorticoid and glucocorticoid receptors in dog brain and pituitary.
    Reul JM, de Kloet ER, van Sluijs FJ, Rijnberk A, Rothuizen J.
    Endocrinology; 1990 Aug 24; 127(2):907-15. PubMed ID: 2164924
    [Abstract] [Full Text] [Related]

  • 19. Relationship of aldosterone synthase gene (C-344T) and mineralocorticoid receptor (S810L) polymorphisms with gestational hypertension.
    Ramírez-Salazar M, Romero-Gutiérrez G, Zaina S, Malacara JM, Kornhauser C, Pérez-Luque E.
    J Hum Hypertens; 2011 May 24; 25(5):320-6. PubMed ID: 20535141
    [Abstract] [Full Text] [Related]

  • 20. A DFT-D investigation of the mechanisms for activation of the wild-type and S810L mutated mineralocorticoid receptor by steroid hormones.
    Riley KE, Hobza P.
    J Phys Chem B; 2008 Mar 13; 112(10):3157-63. PubMed ID: 18284228
    [Abstract] [Full Text] [Related]


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