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645 related items for PubMed ID: 12538627

  • 1. Novel signal transduction pathway for luteinizing hormone and its interaction with insulin: activation of Janus kinase/signal transducer and activator of transcription and phosphoinositol 3-kinase/Akt pathways.
    Carvalho CR, Carvalheira JB, Lima MH, Zimmerman SF, Caperuto LC, Amanso A, Gasparetti AL, Meneghetti V, Zimmerman LF, Velloso LA, Saad MJ.
    Endocrinology; 2003 Feb; 144(2):638-47. PubMed ID: 12538627
    [Abstract] [Full Text] [Related]

  • 2. Stimulation of pancreatic beta-cell proliferation by growth hormone is glucose-dependent: signal transduction via janus kinase 2 (JAK2)/signal transducer and activator of transcription 5 (STAT5) with no crosstalk to insulin receptor substrate-mediated mitogenic signalling.
    Cousin SP, Hügl SR, Myers MG, White MF, Reifel-Miller A, Rhodes CJ.
    Biochem J; 1999 Dec 15; 344 Pt 3(Pt 3):649-58. PubMed ID: 10585851
    [Abstract] [Full Text] [Related]

  • 3. Interaction between leptin and insulin signaling pathways differentially affects JAK-STAT and PI 3-kinase-mediated signaling in rat liver.
    Carvalheira JB, Ribeiro EB, Folli F, Velloso LA, Saad MJ.
    Biol Chem; 2003 Jan 15; 384(1):151-9. PubMed ID: 12674509
    [Abstract] [Full Text] [Related]

  • 4. Suppressor of cytokine signaling-3 Provides a novel interface in the cross-talk between angiotensin II and insulin signaling systems.
    Calegari VC, Alves M, Picardi PK, Inoue RY, Franchini KG, Saad MJ, Velloso LA.
    Endocrinology; 2005 Feb 15; 146(2):579-88. PubMed ID: 15514089
    [Abstract] [Full Text] [Related]

  • 5. The cross-talk between angiotensin and insulin differentially affects phosphatidylinositol 3-kinase- and mitogen-activated protein kinase-mediated signaling in rat heart: implications for insulin resistance.
    Carvalheira JB, Calegari VC, Zecchin HG, Nadruz W, Guimarães RB, Ribeiro EB, Franchini KG, Velloso LA, Saad MJ.
    Endocrinology; 2003 Dec 15; 144(12):5604-14. PubMed ID: 12960006
    [Abstract] [Full Text] [Related]

  • 6. PRL-induced ERalpha gene expression is mediated by Janus kinase 2 (Jak2) while signal transducer and activator of transcription 5b (Stat5b) phosphorylation involves Jak2 and a second tyrosine kinase.
    Frasor J, Barkai U, Zhong L, Fazleabas AT, Gibori G.
    Mol Endocrinol; 2001 Nov 15; 15(11):1941-52. PubMed ID: 11682625
    [Abstract] [Full Text] [Related]

  • 7. Activated STAT5 proteins induce activation of the PI 3-kinase/Akt and Ras/MAPK pathways via the Gab2 scaffolding adapter.
    Nyga R, Pecquet C, Harir N, Gu H, Dhennin-Duthille I, Régnier A, Gouilleux-Gruart V, Lassoued K, Gouilleux F.
    Biochem J; 2005 Aug 15; 390(Pt 1):359-66. PubMed ID: 15833084
    [Abstract] [Full Text] [Related]

  • 8. Insulin receptor substrate-1 enhances growth hormone-induced proliferation.
    Liang L, Zhou T, Jiang J, Pierce JH, Gustafson TA, Frank SJ.
    Endocrinology; 1999 May 15; 140(5):1972-83. PubMed ID: 10218944
    [Abstract] [Full Text] [Related]

  • 9. Growth hormone stimulates tyrosine phosphorylation of JAK2 and STAT5, but not insulin receptor substrate-1 or SHC proteins in liver and skeletal muscle of normal rats in vivo.
    Chow JC, Ling PR, Qu Z, Laviola L, Ciccarone A, Bistrian BR, Smith RJ.
    Endocrinology; 1996 Jul 15; 137(7):2880-6. PubMed ID: 8770909
    [Abstract] [Full Text] [Related]

  • 10. Desensitization of the growth hormone-induced Janus kinase 2 (Jak 2)/signal transducer and activator of transcription 5 (Stat5)-signaling pathway requires protein synthesis and phospholipase C.
    Fernández L, Flores-Morales A, Lahuna O, Sliva D, Norstedt G, Haldosén LA, Mode A, Gustafsson JA.
    Endocrinology; 1998 Apr 15; 139(4):1815-24. PubMed ID: 9528967
    [Abstract] [Full Text] [Related]

  • 11. Interferon-dependent activation of the serine kinase PI 3'-kinase requires engagement of the IRS pathway but not the Stat pathway.
    Uddin S, Majchrzak B, Wang PC, Modi S, Khan MK, Fish EN, Platanias LC.
    Biochem Biophys Res Commun; 2000 Apr 02; 270(1):158-62. PubMed ID: 10733921
    [Abstract] [Full Text] [Related]

  • 12. Insulin receptor substrate-1-mediated enhancement of growth hormone-induced mitogen-activated protein kinase activation.
    Liang L, Jiang J, Frank SJ.
    Endocrinology; 2000 Sep 02; 141(9):3328-36. PubMed ID: 10965905
    [Abstract] [Full Text] [Related]

  • 13. Growth hormone stimulates the tyrosine kinase activity of JAK2 and induces tyrosine phosphorylation of insulin receptor substrates and Shc in rat tissues.
    Thirone AC, Carvalho CR, Saad MJ.
    Endocrinology; 1999 Jan 02; 140(1):55-62. PubMed ID: 9886807
    [Abstract] [Full Text] [Related]

  • 14. Growth hormone (GH)-stimulated insulin-like growth factor I gene expression is mediated by a tyrosine phosphorylation pathway depending on C-terminal region of human GH receptor in human GH receptor-expressing Ba/F3 cells.
    Yoshizato H, Tanaka M, Nakai N, Nakao N, Nakashima K.
    Endocrinology; 2004 Jan 02; 145(1):214-20. PubMed ID: 14551225
    [Abstract] [Full Text] [Related]

  • 15. Prolactin-signal transduction in neonatal rat pancreatic islets and interaction with the insulin-signaling pathway.
    Amaral ME, Ueno M, Carvalheira JB, Carneiro EM, Velloso LA, Saad MJ, Boschero AC.
    Horm Metab Res; 2003 May 02; 35(5):282-9. PubMed ID: 12915997
    [Abstract] [Full Text] [Related]

  • 16. TEL-Syk fusion constitutively activates PI3-K/Akt, MAPK and JAK2-independent STAT5 signal pathways.
    Kanie T, Abe A, Matsuda T, Kuno Y, Towatari M, Yamamoto T, Saito H, Emi N, Naoe T.
    Leukemia; 2004 Mar 02; 18(3):548-55. PubMed ID: 14749700
    [Abstract] [Full Text] [Related]

  • 17. SOCS-3 is involved in the downregulation of the acute insulin-like effects of growth hormone in rat adipocytes by inhibition of Jak2/IRS-1 signaling.
    Ridderstråle M, Amstrup J, Hilton DJ, Billestrup N, Tornqvist H.
    Horm Metab Res; 2003 Mar 02; 35(3):169-77. PubMed ID: 12734778
    [Abstract] [Full Text] [Related]

  • 18. Cross-talk between the insulin and leptin signaling systems in rat hypothalamus.
    Carvalheira JB, Torsoni MA, Ueno M, Amaral ME, Araújo EP, Velloso LA, Gontijo JA, Saad MJ.
    Obes Res; 2005 Jan 02; 13(1):48-57. PubMed ID: 15761162
    [Abstract] [Full Text] [Related]

  • 19. Inadequacy of the Janus kinase 2/signal transducer and activator of transcription signal transduction pathway to mediate episodic growth hormone-dependent regulation of hepatic CYP2C11.
    Verma AS, Dhir RN, Shapiro BH.
    Mol Pharmacol; 2005 Mar 02; 67(3):891-901. PubMed ID: 15591245
    [Abstract] [Full Text] [Related]

  • 20. Regulation of signal transducer and activator of transcription (STAT) 5b activation by the temporal pattern of growth hormone stimulation.
    Gebert CA, Park SH, Waxman DJ.
    Mol Endocrinol; 1997 Apr 02; 11(4):400-14. PubMed ID: 9092792
    [Abstract] [Full Text] [Related]


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