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Journal Abstract Search


250 related items for PubMed ID: 12540610

  • 1. Increased dietary fat promotes islet amyloid formation and beta-cell secretory dysfunction in a transgenic mouse model of islet amyloid.
    Hull RL, Andrikopoulos S, Verchere CB, Vidal J, Wang F, Cnop M, Prigeon RL, Kahn SE.
    Diabetes; 2003 Feb; 52(2):372-9. PubMed ID: 12540610
    [Abstract] [Full Text] [Related]

  • 2. beta-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes.
    Andrikopoulos S, Verchere CB, Terauchi Y, Kadowaki T, Kahn SE.
    Diabetes; 2000 Dec; 49(12):2056-62. PubMed ID: 11118007
    [Abstract] [Full Text] [Related]

  • 3. Alpha1-antitrypsin ameliorates islet amyloid-induced glucose intolerance and β-cell dysfunction.
    Rodríguez-Comas J, Moreno-Vedia J, Obach M, Castaño C, de Pablo S, Alcarraz-Vizán G, Díaz-Catalán D, Mestre A, Horrillo R, Costa M, Novials A, Servitja JM.
    Mol Metab; 2020 Jul; 37():100984. PubMed ID: 32229246
    [Abstract] [Full Text] [Related]

  • 4. Pancreatic expression and secretion of human islet amyloid polypeptide in a transgenic mouse.
    D'Alessio DA, Verchere CB, Kahn SE, Hoagland V, Baskin DG, Palmiter RD, Ensinck JW.
    Diabetes; 1994 Dec; 43(12):1457-61. PubMed ID: 7958499
    [Abstract] [Full Text] [Related]

  • 5. Human islet amyloid polypeptide transgenic mice: in vivo and ex vivo models for the role of hIAPP in type 2 diabetes mellitus.
    Höppener JW, Jacobs HM, Wierup N, Sotthewes G, Sprong M, de Vos P, Berger R, Sundler F, Ahrén B.
    Exp Diabetes Res; 2008 Dec; 2008():697035. PubMed ID: 18497871
    [Abstract] [Full Text] [Related]

  • 6. The islet tissue plasminogen activator/plasmin system is upregulated with human islet amyloid polypeptide aggregation and protects beta cells from aggregation-induced toxicity.
    Esser N, Hogan MF, Templin AT, Akter R, Fountaine BS, Castillo JJ, El-Osta A, Manathunga L, Zhyvoloup A, Raleigh DP, Zraika S, Hull RL, Kahn SE.
    Diabetologia; 2024 Sep; 67(9):1897-1911. PubMed ID: 39245780
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of glycosaminoglycan synthesis and protein glycosylation with WAS-406 and azaserine result in reduced islet amyloid formation in vitro.
    Hull RL, Zraika S, Udayasankar J, Kisilevsky R, Szarek WA, Wight TN, Kahn SE.
    Am J Physiol Cell Physiol; 2007 Nov; 293(5):C1586-93. PubMed ID: 17804609
    [Abstract] [Full Text] [Related]

  • 8. Intra- and extracellular amyloid fibrils are formed in cultured pancreatic islets of transgenic mice expressing human islet amyloid polypeptide.
    de Koning EJ, Morris ER, Hofhuis FM, Posthuma G, Höppener JW, Morris JF, Capel PJ, Clark A, Verbeek JS.
    Proc Natl Acad Sci U S A; 1994 Aug 30; 91(18):8467-71. PubMed ID: 8078905
    [Abstract] [Full Text] [Related]

  • 9. IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction.
    Westwell-Roper C, Dai DL, Soukhatcheva G, Potter KJ, van Rooijen N, Ehses JA, Verchere CB.
    J Immunol; 2011 Sep 01; 187(5):2755-65. PubMed ID: 21813778
    [Abstract] [Full Text] [Related]

  • 10. Postnatally disturbed pancreatic islet cell distribution in human islet amyloid polypeptide transgenic mice.
    Wong HY, Ahrén B, Lips CJ, Höppener JW, Sundler F.
    Regul Pept; 2003 May 15; 113(1-3):89-94. PubMed ID: 12686466
    [Abstract] [Full Text] [Related]

  • 11. Use of the PET ligand florbetapir for in vivo imaging of pancreatic islet amyloid deposits in hIAPP transgenic mice.
    Templin AT, Meier DT, Willard JR, Wolden-Hanson T, Conway K, Lin YG, Gillespie PJ, Bokvist KB, Attardo G, Kahn SE, Scheuner D, Hull RL.
    Diabetologia; 2018 Oct 15; 61(10):2215-2224. PubMed ID: 30046852
    [Abstract] [Full Text] [Related]

  • 12. Identification of the amyloid-degrading enzyme neprilysin in mouse islets and potential role in islet amyloidogenesis.
    Zraika S, Hull RL, Udayasankar J, Clark A, Utzschneider KM, Tong J, Gerchman F, Kahn SE.
    Diabetes; 2007 Feb 15; 56(2):304-10. PubMed ID: 17259373
    [Abstract] [Full Text] [Related]

  • 13. Spontaneous diabetes in hemizygous human amylin transgenic mice that developed neither islet amyloid nor peripheral insulin resistance.
    Wong WP, Scott DW, Chuang CL, Zhang S, Liu H, Ferreira A, Saafi EL, Choong YS, Cooper GJ.
    Diabetes; 2008 Oct 15; 57(10):2737-44. PubMed ID: 18633116
    [Abstract] [Full Text] [Related]

  • 14. Tetracycline treatment retards the onset and slows the progression of diabetes in human amylin/islet amyloid polypeptide transgenic mice.
    Aitken JF, Loomes KM, Scott DW, Reddy S, Phillips AR, Prijic G, Fernando C, Zhang S, Broadhurst R, L'Huillier P, Cooper GJ.
    Diabetes; 2010 Jan 15; 59(1):161-71. PubMed ID: 19794060
    [Abstract] [Full Text] [Related]

  • 15. RIPK3 promotes islet amyloid-induced β-cell loss and glucose intolerance in a humanized mouse model of type 2 diabetes.
    Mukherjee N, Contreras CJ, Lin L, Colglazier KA, Mather EG, Kalwat MA, Esser N, Kahn SE, Templin AT.
    Mol Metab; 2024 Feb 15; 80():101877. PubMed ID: 38218538
    [Abstract] [Full Text] [Related]

  • 16. Amyloid-induced β-cell dysfunction and islet inflammation are ameliorated by 4-phenylbutyrate (PBA) treatment.
    Montane J, de Pablo S, Castaño C, Rodríguez-Comas J, Cadavez L, Obach M, Visa M, Alcarraz-Vizán G, Sanchez-Martinez M, Nonell-Canals A, Parrizas M, Servitja JM, Novials A.
    FASEB J; 2017 Dec 15; 31(12):5296-5306. PubMed ID: 28821639
    [Abstract] [Full Text] [Related]

  • 17. Islet amyloid: a complication of islet dysfunction or an aetiological factor in Type 2 diabetes?
    Clark A, Nilsson MR.
    Diabetologia; 2004 Feb 15; 47(2):157-69. PubMed ID: 14722650
    [Abstract] [Full Text] [Related]

  • 18. IL-1 mediates amyloid-associated islet dysfunction and inflammation in human islet amyloid polypeptide transgenic mice.
    Westwell-Roper CY, Chehroudi CA, Denroche HC, Courtade JA, Ehses JA, Verchere CB.
    Diabetologia; 2015 Mar 15; 58(3):575-85. PubMed ID: 25491100
    [Abstract] [Full Text] [Related]

  • 19. The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets.
    Meier DT, Entrup L, Templin AT, Hogan MF, Mellati M, Zraika S, Hull RL, Kahn SE.
    Diabetologia; 2016 Oct 15; 59(10):2166-71. PubMed ID: 27393137
    [Abstract] [Full Text] [Related]

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