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Journal Abstract Search

312 related items for PubMed ID: 12540902

  • 1. Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders.
    Sánchez I, Mahlke C, Yuan J.
    Nature; 2003 Jan 23; 421(6921):373-9. PubMed ID: 12540902
    [Abstract] [Full Text] [Related]

  • 2. Effects of overexpression of huntingtin proteins on mitochondrial integrity.
    Wang H, Lim PJ, Karbowski M, Monteiro MJ.
    Hum Mol Genet; 2009 Feb 15; 18(4):737-52. PubMed ID: 19039036
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  • 3. Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release.
    Jana NR, Zemskov EA, Wang Gh, Nukina N.
    Hum Mol Genet; 2001 May 01; 10(10):1049-59. PubMed ID: 11331615
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  • 4. Amyloid formation by mutant huntingtin: threshold, progressivity and recruitment of normal polyglutamine proteins.
    Huang CC, Faber PW, Persichetti F, Mittal V, Vonsattel JP, MacDonald ME, Gusella JF.
    Somat Cell Mol Genet; 1998 Jul 01; 24(4):217-33. PubMed ID: 10410676
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  • 5. Polyglutamine disease: acetyltransferases awry.
    Hughes RE.
    Curr Biol; 2002 Feb 19; 12(4):R141-3. PubMed ID: 11864588
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  • 8. Transgenic mice expressing mutated full-length HD cDNA: a paradigm for locomotor changes and selective neuronal loss in Huntington's disease.
    Reddy PH, Charles V, Williams M, Miller G, Whetsell WO, Tagle DA.
    Philos Trans R Soc Lond B Biol Sci; 1999 Jun 29; 354(1386):1035-45. PubMed ID: 10434303
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  • 10. Properties of polyglutamine expansion in vitro and in a cellular model for Huntington's disease.
    Lunkes A, Trottier Y, Fagart J, Schultz P, Zeder-Lutz G, Moras D, Mandel JL.
    Philos Trans R Soc Lond B Biol Sci; 1999 Jun 29; 354(1386):1013-9. PubMed ID: 10434300
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  • 12. Nuclear localization of a non-caspase truncation product of atrophin-1, with an expanded polyglutamine repeat, increases cellular toxicity.
    Nucifora FC, Ellerby LM, Wellington CL, Wood JD, Herring WJ, Sawa A, Hayden MR, Dawson VL, Dawson TM, Ross CA.
    J Biol Chem; 2003 Apr 11; 278(15):13047-55. PubMed ID: 12464607
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  • 13. Extended polyglutamine selectively interacts with caspase-8 and -10 in nuclear aggregates.
    U M, Miyashita T, Ohtsuka Y, Okamura-Oho Y, Shikama Y, Yamada M.
    Cell Death Differ; 2001 Apr 11; 8(4):377-86. PubMed ID: 11550089
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  • 14. Transgenic mouse models of neurodegenerative disease caused by CAG/polyglutamine expansions.
    Bates GP, Davies SW.
    Mol Med Today; 1997 Nov 11; 3(11):508-15. PubMed ID: 9430787
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  • 16. Identification of novel potentially toxic oligomers formed in vitro from mammalian-derived expanded huntingtin exon-1 protein.
    Nucifora LG, Burke KA, Feng X, Arbez N, Zhu S, Miller J, Yang G, Ratovitski T, Delannoy M, Muchowski PJ, Finkbeiner S, Legleiter J, Ross CA, Poirier MA.
    J Biol Chem; 2012 May 04; 287(19):16017-28. PubMed ID: 22433867
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  • 17. Lack of RAN-mediated toxicity in Huntington's disease knock-in mice.
    Yang S, Yang H, Huang L, Chen L, Qin Z, Li S, Li XJ.
    Proc Natl Acad Sci U S A; 2020 Feb 25; 117(8):4411-4417. PubMed ID: 32029588
    [Abstract] [Full Text] [Related]

  • 18. Amino acid sequences flanking polyglutamine stretches influence their potential for aggregate formation.
    Nozaki K, Onodera O, Takano H, Tsuji S.
    Neuroreport; 2001 Oct 29; 12(15):3357-64. PubMed ID: 11711886
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  • 19. BAG-1 associates with the polyglutamine-expanded huntingtin aggregates.
    Jana NR, Nukina N.
    Neurosci Lett; 2005 Apr 22; 378(3):171-5. PubMed ID: 15781153
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  • 20. Antisense oligonucleotide therapeutics in neurodegenerative diseases: the case of polyglutamine disorders.
    Silva AC, Lobo DD, Martins IM, Lopes SM, Henriques C, Duarte SP, Dodart JC, Nobre RJ, Pereira de Almeida L.
    Brain; 2020 Feb 01; 143(2):407-429. PubMed ID: 31738395
    [Abstract] [Full Text] [Related]

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