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161 related items for PubMed ID: 12543077

  • 1. SHP2 regulates IL-2 induced MAPK activation, but not Stat3 or Stat5 tyrosine phosphorylation, in cutaneous T cell lymphoma cells.
    Lundin Brockdorff J, Woetmann A, Mustelin T, Kaltoft K, Zhang Q, Wasik MA, Röpke C, Ødum N.
    Cytokine; 2002 Nov 24; 20(4):141-7. PubMed ID: 12543077
    [Abstract] [Full Text] [Related]

  • 2. TNF-alpha induces tyrosine phosphorylation and recruitment of the Src homology protein-tyrosine phosphatase 2 to the gp130 signal-transducing subunit of the IL-6 receptor complex.
    Bode JG, Schweigart J, Kehrmann J, Ehlting C, Schaper F, Heinrich PC, Häussinger D.
    J Immunol; 2003 Jul 01; 171(1):257-66. PubMed ID: 12817006
    [Abstract] [Full Text] [Related]

  • 3. Activation of the Jak-Stat- and MAPK-pathways by oncostatin M is not sufficient to cause growth inhibition of human glioma cells.
    Halfter H, Postert C, Friedrich M, Ringelstein EB, Stögbauer F.
    Brain Res Mol Brain Res; 2000 Sep 15; 80(2):198-206. PubMed ID: 11038252
    [Abstract] [Full Text] [Related]

  • 4. Gab2 is phosphorylated on tyrosine upon interleukin-2/interleukin-15 stimulation in mycosis-fungoides-derived tumor T cells and associates inducibly with SHP-2 and Stat5a.
    Brockdorff JL, Gu H, Mustelin T, Kaltoft K, Geisler C, Röpke C, Ødum N.
    Exp Clin Immunogenet; 2001 Sep 15; 18(2):86-95. PubMed ID: 11340297
    [Abstract] [Full Text] [Related]

  • 5. Phosphorylation of Grb2-associated binder 2 on serine 623 by ERK MAPK regulates its association with the phosphatase SHP-2 and decreases STAT5 activation.
    Arnaud M, Crouin C, Deon C, Loyaux D, Bertoglio J.
    J Immunol; 2004 Sep 15; 173(6):3962-71. PubMed ID: 15356145
    [Abstract] [Full Text] [Related]

  • 6. Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression.
    Schaper F, Gendo C, Eck M, Schmitz J, Grimm C, Anhuf D, Kerr IM, Heinrich PC.
    Biochem J; 1998 Nov 01; 335 ( Pt 3)(Pt 3):557-65. PubMed ID: 9794795
    [Abstract] [Full Text] [Related]

  • 7. Differential constitutive activation between STAT-related proteins and MAP kinase in primary acute myelogenous leukaemia.
    Hayakawa F, Towatari M, Iida H, Wakao H, Kiyoi H, Naoe T, Saito H.
    Br J Haematol; 1998 Jun 01; 101(3):521-8. PubMed ID: 9633897
    [Abstract] [Full Text] [Related]

  • 8. Differences in phosphorylation of the IL-2R associated JAK/STAT proteins between HTLV-I(+), IL-2-independent and IL-2-dependent cell lines and uncultured leukemic cells from patients with adult T-cell lymphoma/leukemia.
    Zhang Q, Lee B, Korecka M, Li G, Weyland C, Eck S, Gessain A, Arima N, Lessin SR, Shaw LM, Luger S, Kamoun M, Wasik MA.
    Leuk Res; 1999 Apr 01; 23(4):373-84. PubMed ID: 10229324
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of PTPs by H(2)O(2) regulates the activation of distinct MAPK pathways.
    Lee K, Esselman WJ.
    Free Radic Biol Med; 2002 Oct 15; 33(8):1121-32. PubMed ID: 12374624
    [Abstract] [Full Text] [Related]

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  • 11. Thrombopoietin, but not cytokines binding to gp130 protein-coupled receptors, activates MAPKp42/44, AKT, and STAT proteins in normal human CD34+ cells, megakaryocytes, and platelets.
    Majka M, Ratajczak J, Villaire G, Kubiczek K, Marquez LA, Janowska-Wieczorek A, Ratajczak MZ.
    Exp Hematol; 2002 Jul 15; 30(7):751-60. PubMed ID: 12135673
    [Abstract] [Full Text] [Related]

  • 12. Cytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulation.
    Yu CL, Jin YJ, Burakoff SJ.
    J Biol Chem; 2000 Jan 07; 275(1):599-604. PubMed ID: 10617656
    [Abstract] [Full Text] [Related]

  • 13. Transforming growth factor-beta1 interferes with thrombopoietin-induced signal transduction in megakaryoblastic and erythroleukemic cells.
    Kalina U, Koschmieder S, Hofmann WK, Wagner S, Kauschat D, Hoelzer D, Ottmann OG.
    Exp Hematol; 2001 May 07; 29(5):602-8. PubMed ID: 11376873
    [Abstract] [Full Text] [Related]

  • 14. Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells.
    Badache A, Hynes NE.
    Cancer Res; 2001 Jan 01; 61(1):383-91. PubMed ID: 11196191
    [Abstract] [Full Text] [Related]

  • 15. Downstream effectors of oncogenic ras in multiple myeloma cells.
    Hu L, Shi Y, Hsu JH, Gera J, Van Ness B, Lichtenstein A.
    Blood; 2003 Apr 15; 101(8):3126-35. PubMed ID: 12515720
    [Abstract] [Full Text] [Related]

  • 16. Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway.
    Beadling C, Ng J, Babbage JW, Cantrell DA.
    EMBO J; 1996 Apr 15; 15(8):1902-13. PubMed ID: 8617237
    [Abstract] [Full Text] [Related]

  • 17. The protein tyrosine phosphatase, Shp2, is required for the complete activation of the RAS/MAPK pathway by brain-derived neurotrophic factor.
    Easton JB, Royer AR, Middlemas DS.
    J Neurochem; 2006 May 15; 97(3):834-45. PubMed ID: 16573649
    [Abstract] [Full Text] [Related]

  • 18. Protein tyrosine phosphatase epsilonC selectively inhibits interleukin-6- and interleukin- 10-induced JAK-STAT signaling.
    Tanuma N, Shima H, Nakamura K, Kikuchi K.
    Blood; 2001 Nov 15; 98(10):3030-4. PubMed ID: 11698287
    [Abstract] [Full Text] [Related]

  • 19. Role of the protein tyrosine phosphatase SHP-1 (Src homology phosphatase-1) in the regulation of interleukin-3-induced survival, proliferation and signalling.
    Paling NR, Welham MJ.
    Biochem J; 2002 Dec 15; 368(Pt 3):885-94. PubMed ID: 12220225
    [Abstract] [Full Text] [Related]

  • 20. TEL-Syk fusion constitutively activates PI3-K/Akt, MAPK and JAK2-independent STAT5 signal pathways.
    Kanie T, Abe A, Matsuda T, Kuno Y, Towatari M, Yamamoto T, Saito H, Emi N, Naoe T.
    Leukemia; 2004 Mar 15; 18(3):548-55. PubMed ID: 14749700
    [Abstract] [Full Text] [Related]

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