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123 related items for PubMed ID: 12555073

  • 1. An inhibitory function for JNK in the regulation of IGF-I signaling in breast cancer.
    Mamay CL, Mingo-Sion AM, Wolf DM, Molina MD, Van Den Berg CL.
    Oncogene; 2003 Jan 30; 22(4):602-14. PubMed ID: 12555073
    [Abstract] [Full Text] [Related]

  • 2. A chimeric humanized single-chain antibody against the type I insulin-like growth factor (IGF) receptor renders breast cancer cells refractory to the mitogenic effects of IGF-I.
    Sachdev D, Li SL, Hartell JS, Fujita-Yamaguchi Y, Miller JS, Yee D.
    Cancer Res; 2003 Feb 01; 63(3):627-35. PubMed ID: 12566306
    [Abstract] [Full Text] [Related]

  • 3. Epidermal growth factor induces insulin receptor substrate-2 in breast cancer cells via c-Jun NH(2)-terminal kinase/activator protein-1 signaling to regulate cell migration.
    Cui X, Kim HJ, Kuiatse I, Kim H, Brown PH, Lee AV.
    Cancer Res; 2006 May 15; 66(10):5304-13. PubMed ID: 16707456
    [Abstract] [Full Text] [Related]

  • 4. Differential insulin-like growth factor I receptor signaling and function in estrogen receptor (ER)-positive MCF-7 and ER-negative MDA-MB-231 breast cancer cells.
    Bartucci M, Morelli C, Mauro L, Andò S, Surmacz E.
    Cancer Res; 2001 Sep 15; 61(18):6747-54. PubMed ID: 11559546
    [Abstract] [Full Text] [Related]

  • 5. IRS-1 expression and activation are not sufficient to activate downstream pathways and enable IGF-I growth response in estrogen receptor negative breast cancer cells.
    Jackson JG, Yee D.
    Growth Horm IGF Res; 1999 Oct 15; 9(5):280-9. PubMed ID: 10543935
    [Abstract] [Full Text] [Related]

  • 6. Phosphatidylinositol 3-kinase (PI-3K)/Akt but not PI-3K/p70 S6 kinase signaling mediates IGF-1-promoted lens epithelial cell survival.
    Chandrasekher G, Sailaja D.
    Invest Ophthalmol Vis Sci; 2004 Oct 15; 45(10):3577-88. PubMed ID: 15452065
    [Abstract] [Full Text] [Related]

  • 7. PKCdelta and mTOR interact to regulate stress and IGF-I induced IRS-1 Ser312 phosphorylation in breast cancer cells.
    Mingo-Sion AM, Ferguson HA, Koller E, Reyland ME, Van Den Berg CL.
    Breast Cancer Res Treat; 2005 Jun 15; 91(3):259-69. PubMed ID: 15952059
    [Abstract] [Full Text] [Related]

  • 8. IGF-1 activates hEAG K(+) channels through an Akt-dependent signaling pathway in breast cancer cells: role in cell proliferation.
    Borowiec AS, Hague F, Harir N, Guénin S, Guerineau F, Gouilleux F, Roudbaraki M, Lassoued K, Ouadid-Ahidouch H.
    J Cell Physiol; 2007 Sep 15; 212(3):690-701. PubMed ID: 17520698
    [Abstract] [Full Text] [Related]

  • 9. Retinoic acid-induced growth arrest of MCF-7 cells involves the selective regulation of the IRS-1/PI 3-kinase/AKT pathway.
    del Rincón SV, Rousseau C, Samanta R, Miller WH.
    Oncogene; 2003 May 29; 22(22):3353-60. PubMed ID: 12776186
    [Abstract] [Full Text] [Related]

  • 10. Overexpressed IGF-I receptors reduce estrogen growth requirements, enhance survival, and promote E-cadherin-mediated cell-cell adhesion in human breast cancer cells.
    Guvakova MA, Surmacz E.
    Exp Cell Res; 1997 Feb 25; 231(1):149-62. PubMed ID: 9056422
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of in vivo breast cancer growth by antisense oligodeoxynucleotides to type I insulin-like growth factor receptor mRNA involves inactivation of ErbBs, PI-3K/Akt and p42/p44 MAPK signaling pathways but not modulation of progesterone receptor activity.
    Salatino M, Schillaci R, Proietti CJ, Carnevale R, Frahm I, Molinolo AA, Iribarren A, Charreau EH, Elizalde PV.
    Oncogene; 2004 Jul 01; 23(30):5161-74. PubMed ID: 15122317
    [Abstract] [Full Text] [Related]

  • 12. RNAi-mediated silencing of insulin receptor substrate 1 (IRS-1) enhances tamoxifen-induced cell death in MCF-7 breast cancer cells.
    Cesarone G, Garofalo C, Abrams MT, Igoucheva O, Alexeev V, Yoon K, Surmacz E, Wickstrom E.
    J Cell Biochem; 2006 May 15; 98(2):440-50. PubMed ID: 16440325
    [Abstract] [Full Text] [Related]

  • 13. Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.
    Batty IH, Fleming IN, Downes CP.
    Biochem J; 2004 May 01; 379(Pt 3):641-51. PubMed ID: 14769130
    [Abstract] [Full Text] [Related]

  • 14. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.
    Menendez JA, Mehmi I, Atlas E, Colomer R, Lupu R.
    Int J Oncol; 2004 Mar 01; 24(3):591-608. PubMed ID: 14767544
    [Abstract] [Full Text] [Related]

  • 15. Sequential phosphorylation of insulin receptor substrate-2 by glycogen synthase kinase-3 and c-Jun NH2-terminal kinase plays a role in hepatic insulin signaling.
    Sharfi H, Eldar-Finkelman H.
    Am J Physiol Endocrinol Metab; 2008 Feb 01; 294(2):E307-15. PubMed ID: 18029441
    [Abstract] [Full Text] [Related]

  • 16. Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines.
    Jackson JG, Zhang X, Yoneda T, Yee D.
    Oncogene; 2001 Nov 01; 20(50):7318-25. PubMed ID: 11704861
    [Abstract] [Full Text] [Related]

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  • 19. Insulin and insulin-like growth factor-I (IGF-I) receptor overexpression in breast cancers leads to insulin/IGF-I hybrid receptor overexpression: evidence for a second mechanism of IGF-I signaling.
    Pandini G, Vigneri R, Costantino A, Frasca F, Ippolito A, Fujita-Yamaguchi Y, Siddle K, Goldfine ID, Belfiore A.
    Clin Cancer Res; 1999 Jul 01; 5(7):1935-44. PubMed ID: 10430101
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