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130 related items for PubMed ID: 12556225

  • 1. Tailoring tissue inhibitor of metalloproteinases-3 to overcome the weakening effects of the cysteine-rich domains of tumour necrosis factor-alpha converting enzyme.
    Lee MH, Dodds P, Verma V, Maskos K, Knäuper V, Murphy G.
    Biochem J; 2003 Apr 15; 371(Pt 2):369-76. PubMed ID: 12556225
    [Abstract] [Full Text] [Related]

  • 2. Full-length and N-TIMP-3 display equal inhibitory activities toward TNF-alpha convertase.
    Lee MH, Knäuper V, Becherer JD, Murphy G.
    Biochem Biophys Res Commun; 2001 Jan 26; 280(3):945-50. PubMed ID: 11162616
    [Abstract] [Full Text] [Related]

  • 3. Engineering N-terminal domain of tissue inhibitor of metalloproteinase (TIMP)-3 to be a better inhibitor against tumour necrosis factor-alpha-converting enzyme.
    Lee MH, Verma V, Maskos K, Nath D, Knäuper V, Dodds P, Amour A, Murphy G.
    Biochem J; 2002 May 15; 364(Pt 1):227-34. PubMed ID: 11988096
    [Abstract] [Full Text] [Related]

  • 4. The C-terminal domains of TACE weaken the inhibitory action of N-TIMP-3.
    Lee MH, Verma V, Maskos K, Becherer JD, Knäuper V, Dodds P, Amour A, Murphy G.
    FEBS Lett; 2002 Jun 05; 520(1-3):102-6. PubMed ID: 12044879
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of the tumor necrosis factor-alpha-converting enzyme by its pro domain.
    Gonzales PE, Solomon A, Miller AB, Leesnitzer MA, Sagi I, Milla ME.
    J Biol Chem; 2004 Jul 23; 279(30):31638-45. PubMed ID: 15100227
    [Abstract] [Full Text] [Related]

  • 6. Mapping and characterization of the functional epitopes of tissue inhibitor of metalloproteinases (TIMP)-3 using TIMP-1 as the scaffold: a new frontier in TIMP engineering.
    Lee MH, Maskos K, Knäuper V, Dodds P, Murphy G.
    Protein Sci; 2002 Oct 23; 11(10):2493-503. PubMed ID: 12237470
    [Abstract] [Full Text] [Related]

  • 7. TNF-alpha converting enzyme (TACE) is inhibited by TIMP-3.
    Amour A, Slocombe PM, Webster A, Butler M, Knight CG, Smith BJ, Stephens PE, Shelley C, Hutton M, Knäuper V, Docherty AJ, Murphy G.
    FEBS Lett; 1998 Sep 11; 435(1):39-44. PubMed ID: 9755855
    [Abstract] [Full Text] [Related]

  • 8. Delineating the molecular basis of the inactivity of tissue inhibitor of metalloproteinase-2 against tumor necrosis factor-alpha-converting enzyme.
    Lee MH, Rapti M, Murphy G.
    J Biol Chem; 2004 Oct 22; 279(43):45121-9. PubMed ID: 15308656
    [Abstract] [Full Text] [Related]

  • 9. Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex.
    Wisniewska M, Goettig P, Maskos K, Belouski E, Winters D, Hecht R, Black R, Bode W.
    J Mol Biol; 2008 Sep 19; 381(5):1307-19. PubMed ID: 18638486
    [Abstract] [Full Text] [Related]

  • 10. Catalytic properties of ADAM12 and its domain deletion mutants.
    Jacobsen J, Visse R, Sørensen HP, Enghild JJ, Brew K, Wewer UM, Nagase H.
    Biochemistry; 2008 Jan 15; 47(2):537-47. PubMed ID: 18081311
    [Abstract] [Full Text] [Related]

  • 11. Reactive site mutations in tissue inhibitor of metalloproteinase-3 disrupt inhibition of matrix metalloproteinases but not tumor necrosis factor-alpha-converting enzyme.
    Wei S, Kashiwagi M, Kota S, Xie Z, Nagase H, Brew K.
    J Biol Chem; 2005 Sep 23; 280(38):32877-82. PubMed ID: 16079149
    [Abstract] [Full Text] [Related]

  • 12. Total conversion of tissue inhibitor of metalloproteinase (TIMP) for specific metalloproteinase targeting: fine-tuning TIMP-4 for optimal inhibition of tumor necrosis factor-{alpha}-converting enzyme.
    Lee MH, Rapti M, Murphy G.
    J Biol Chem; 2005 Apr 22; 280(16):15967-75. PubMed ID: 15713681
    [Abstract] [Full Text] [Related]

  • 13. Drosophila TIMP is a potent inhibitor of MMPs and TACE: similarities in structure and function to TIMP-3.
    Wei S, Xie Z, Filenova E, Brew K.
    Biochemistry; 2003 Oct 28; 42(42):12200-7. PubMed ID: 14567681
    [Abstract] [Full Text] [Related]

  • 14. Specific sequence elements are required for the expression of functional tumor necrosis factor-alpha-converting enzyme (TACE).
    Milla ME, Leesnitzer MA, Moss ML, Clay WC, Carter HL, Miller AB, Su JL, Lambert MH, Willard DH, Sheeley DM, Kost TA, Burkhart W, Moyer M, Blackburn RK, Pahel GL, Mitchell JL, Hoffman CR, Becherer JD.
    J Biol Chem; 1999 Oct 22; 274(43):30563-70. PubMed ID: 10521439
    [Abstract] [Full Text] [Related]

  • 15. Pronounced diversity in electronic and chemical properties between the catalytic zinc sites of tumor necrosis factor-alpha-converting enzyme and matrix metalloproteinases despite their high structural similarity.
    Solomon A, Rosenblum G, Gonzales PE, Leonard JD, Mobashery S, Milla ME, Sagi I.
    J Biol Chem; 2004 Jul 23; 279(30):31646-54. PubMed ID: 15102849
    [Abstract] [Full Text] [Related]

  • 16. Site-directed mutations that alter the inhibitory activity of the tissue inhibitor of metalloproteinases-1: importance of the N-terminal region between cysteine 3 and cysteine 13.
    O'Shea M, Willenbrock F, Williamson RA, Cockett MI, Freedman RB, Reynolds JJ, Docherty AJ, Murphy G.
    Biochemistry; 1992 Oct 27; 31(42):10146-52. PubMed ID: 1420137
    [Abstract] [Full Text] [Related]

  • 17. The in vitro activity of ADAM-10 is inhibited by TIMP-1 and TIMP-3.
    Amour A, Knight CG, Webster A, Slocombe PM, Stephens PE, Knäuper V, Docherty AJ, Murphy G.
    FEBS Lett; 2000 May 19; 473(3):275-9. PubMed ID: 10818225
    [Abstract] [Full Text] [Related]

  • 18. Threonine 98, the pivotal residue of tissue inhibitor of metalloproteinases (TIMP)-1 in metalloproteinase recognition.
    Lee MH, Rapti M, Knaüper V, Murphy G.
    J Biol Chem; 2004 Apr 23; 279(17):17562-9. PubMed ID: 14734567
    [Abstract] [Full Text] [Related]

  • 19. Multiple metalloproteinases process protransforming growth factor-alpha (proTGF-alpha).
    Hinkle CL, Mohan MJ, Lin P, Yeung N, Rasmussen F, Milla ME, Moss ML.
    Biochemistry; 2003 Feb 25; 42(7):2127-36. PubMed ID: 12590602
    [Abstract] [Full Text] [Related]

  • 20. CD30 shedding from Karpas 299 lymphoma cells is mediated by TNF-alpha-converting enzyme.
    Hansen HP, Dietrich S, Kisseleva T, Mokros T, Mentlein R, Lange HH, Murphy G, Lemke H.
    J Immunol; 2000 Dec 15; 165(12):6703-9. PubMed ID: 11120787
    [Abstract] [Full Text] [Related]

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