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112 related items for PubMed ID: 12559174

  • 1. The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice.
    Gladdy RA, Taylor MD, Williams CJ, Grandal I, Karaskova J, Squire JA, Rutka JT, Guidos CJ, Danska JS.
    Cancer Cell; 2003 Jan; 3(1):37-50. PubMed ID: 12559174
    [Abstract] [Full Text] [Related]

  • 2. Tp53 deletion in B lineage cells predisposes mice to lymphomas with oncogenic translocations.
    Rowh MA, DeMicco A, Horowitz JE, Yin B, Yang-Iott KS, Fusello AM, Hobeika E, Reth M, Bassing CH.
    Oncogene; 2011 Nov 24; 30(47):4757-64. PubMed ID: 21625223
    [Abstract] [Full Text] [Related]

  • 3. Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.
    Zhu C, Mills KD, Ferguson DO, Lee C, Manis J, Fleming J, Gao Y, Morton CC, Alt FW.
    Cell; 2002 Jun 28; 109(7):811-21. PubMed ID: 12110179
    [Abstract] [Full Text] [Related]

  • 4. Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification.
    Difilippantonio MJ, Petersen S, Chen HT, Johnson R, Jasin M, Kanaar R, Ried T, Nussenzweig A.
    J Exp Med; 2002 Aug 19; 196(4):469-80. PubMed ID: 12186839
    [Abstract] [Full Text] [Related]

  • 5. Amplification of IGH/MYC fusion in clinically aggressive IGH/BCL2-positive germinal center B-cell lymphomas.
    Martín-Subero JI, Odero MD, Hernandez R, Cigudosa JC, Agirre X, Saez B, Sanz-García E, Ardanaz MT, Novo FJ, Gascoyne RD, Calasanz MJ, Siebert R.
    Genes Chromosomes Cancer; 2005 Aug 19; 43(4):414-23. PubMed ID: 15852472
    [Abstract] [Full Text] [Related]

  • 6. Ku80 and p53 suppress medulloblastoma that arise independent of Rag-1-induced DSBs.
    Holcomb VB, Vogel H, Marple T, Kornegay RW, Hasty P.
    Oncogene; 2006 Nov 16; 25(54):7159-65. PubMed ID: 16751807
    [Abstract] [Full Text] [Related]

  • 7. Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.
    Ramiro AR, Jankovic M, Callen E, Difilippantonio S, Chen HT, McBride KM, Eisenreich TR, Chen J, Dickins RA, Lowe SW, Nussenzweig A, Nussenzweig MC.
    Nature; 2006 Mar 02; 440(7080):105-9. PubMed ID: 16400328
    [Abstract] [Full Text] [Related]

  • 8. Artemis and p53 cooperate to suppress oncogenic N-myc amplification in progenitor B cells.
    Rooney S, Sekiguchi J, Whitlow S, Eckersdorff M, Manis JP, Lee C, Ferguson DO, Alt FW.
    Proc Natl Acad Sci U S A; 2004 Feb 24; 101(8):2410-5. PubMed ID: 14983023
    [Abstract] [Full Text] [Related]

  • 9. A p53 defect sensitizes various stages of B cell development to lymphomagenesis in mice carrying an IgH 3' regulatory region-driven c-myc transgene.
    Fiancette R, Rouaud P, Vincent-Fabert C, Laffleur B, Magnone V, Cogné M, Denizot Y.
    J Immunol; 2011 Dec 01; 187(11):5772-82. PubMed ID: 22039300
    [Abstract] [Full Text] [Related]

  • 10. Combined deletion of Xrcc4 and Trp53 in mouse germinal center B cells leads to novel B cell lymphomas with clonal heterogeneity.
    Chen Z, Elos MT, Viboolsittiseri SS, Gowan K, Leach SM, Rice M, Eder MD, Jones K, Wang JH.
    J Hematol Oncol; 2016 Jan 07; 9():2. PubMed ID: 26740101
    [Abstract] [Full Text] [Related]

  • 11. Molecular-cytogenetic characterization of non-Hodgkin's lymphoma with double and cryptic translocations of the immunoglobulin heavy chain gene.
    Kanda-Akano Y, Nomura K, Fujita Y, Horiike S, Nishida K, Nagai M, Miura I, Nakamura S, Seto M, Iida S, Ueda R, Taniwaki M.
    Leuk Lymphoma; 2004 Aug 07; 45(8):1559-67. PubMed ID: 15370207
    [Abstract] [Full Text] [Related]

  • 12. H2AX prevents DNA breaks from progressing to chromosome breaks and translocations.
    Franco S, Gostissa M, Zha S, Lombard DB, Murphy MM, Zarrin AA, Yan C, Tepsuporn S, Morales JC, Adams MM, Lou Z, Bassing CH, Manis JP, Chen J, Carpenter PB, Alt FW.
    Mol Cell; 2006 Jan 20; 21(2):201-14. PubMed ID: 16427010
    [Abstract] [Full Text] [Related]

  • 13. Genetic pathway to recurrent chromosome translocations in murine lymphoma involves V(D)J recombinase.
    Vanasse GJ, Halbrook J, Thomas S, Burgess A, Hoekstra MF, Disteche CM, Willerford DM.
    J Clin Invest; 1999 Jun 20; 103(12):1669-75. PubMed ID: 10377173
    [Abstract] [Full Text] [Related]

  • 14. XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice.
    Yan CT, Kaushal D, Murphy M, Zhang Y, Datta A, Chen C, Monroe B, Mostoslavsky G, Coakley K, Gao Y, Mills KD, Fazeli AP, Tepsuporn S, Hall G, Mulligan R, Fox E, Bronson R, De Girolami U, Lee C, Alt FW.
    Proc Natl Acad Sci U S A; 2006 May 09; 103(19):7378-83. PubMed ID: 16670198
    [Abstract] [Full Text] [Related]

  • 15. Breakage-Fusion-Bridge Events Trigger Complex Genome Rearrangements and Amplifications in Developmentally Arrested T Cell Lymphomas.
    Bianchi JJ, Murigneux V, Bedora-Faure M, Lescale C, Deriano L.
    Cell Rep; 2019 Jun 04; 27(10):2847-2858.e4. PubMed ID: 31167132
    [Abstract] [Full Text] [Related]

  • 16. Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70.
    Weinstock DM, Brunet E, Jasin M.
    Nat Cell Biol; 2007 Aug 04; 9(8):978-81. PubMed ID: 17643113
    [Abstract] [Full Text] [Related]

  • 17. Insertion of c-Myc into Igh induces B-cell and plasma-cell neoplasms in mice.
    Park SS, Kim JS, Tessarollo L, Owens JD, Peng L, Han SS, Tae Chung S, Torrey TA, Cheung WC, Polakiewicz RD, McNeil N, Ried T, Mushinski JF, Morse HC, Janz S.
    Cancer Res; 2005 Feb 15; 65(4):1306-15. PubMed ID: 15735016
    [Abstract] [Full Text] [Related]

  • 18. Genomic instability in B-cells and diversity of recombinations that activate c-myc.
    Janz S, Jones GM, Müller JR, Potter M.
    Curr Top Microbiol Immunol; 1995 Feb 15; 194():373-80. PubMed ID: 7895512
    [Abstract] [Full Text] [Related]

  • 19. Novel three-break rearrangement and cryptic translocations leading to colocalization of MYC and IGH signals in B-cell acute lymphoblastic leukemia.
    Tchinda J, Volpert S, Berdel WE, Büchner T, Horst J.
    Cancer Genet Cytogenet; 2006 Mar 15; 165(2):180-4. PubMed ID: 16527615
    [Abstract] [Full Text] [Related]

  • 20. Genomic instability and apoptosis are frequent in p53 deficient young mice.
    Fukasawa K, Wiener F, Vande Woude GF, Mai S.
    Oncogene; 1997 Sep 15; 15(11):1295-302. PubMed ID: 9315097
    [Abstract] [Full Text] [Related]

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