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231 related items for PubMed ID: 12559694

  • 1. A toxicokinetic model for styrene and its metabolite styrene-7,8-oxide in mouse, rat and human with special emphasis on the lung.
    Csanády GA, Kessler W, Hoffmann HD, Filser JG.
    Toxicol Lett; 2003 Feb 18; 138(1-2):75-102. PubMed ID: 12559694
    [Abstract] [Full Text] [Related]

  • 2. A physiological toxicokinetic model for inhaled propylene oxide in rat and human with special emphasis on the nose.
    Csanády GA, Filser JG.
    Toxicol Sci; 2007 Jan 18; 95(1):37-62. PubMed ID: 17062723
    [Abstract] [Full Text] [Related]

  • 3. Styrene-7,8-oxide burden in ventilated, perfused lungs of mice and rats exposed to vaporous styrene.
    Hofmann C, Pütz C, Semder B, Faller TH, Csanády GA, Filser JG.
    Toxicol Sci; 2006 Mar 18; 90(1):39-48. PubMed ID: 16322077
    [Abstract] [Full Text] [Related]

  • 4. DNA adducts of styrene-7,8-oxide in target and non-target organs for tumor induction in rat and mouse after repeated inhalation exposure to styrene.
    Otteneder M, Lutz U, Lutz WK.
    Mutat Res; 2002 Mar 20; 500(1-2):111-6. PubMed ID: 11890940
    [Abstract] [Full Text] [Related]

  • 5. Quantification of DNA adducts formed in liver, lungs, and isolated lung cells of rats and mice exposed to (14)C-styrene by nose-only inhalation.
    Boogaard PJ, de Kloe KP, Wong BA, Sumner SC, Watson WP, van Sittert NJ.
    Toxicol Sci; 2000 Oct 20; 57(2):203-16. PubMed ID: 11006351
    [Abstract] [Full Text] [Related]

  • 6. A physiological toxicokinetic model for exogenous and endogenous ethylene and ethylene oxide in rat, mouse, and human: formation of 2-hydroxyethyl adducts with hemoglobin and DNA.
    Csanády GA, Denk B, Pütz C, Kreuzer PE, Kessler W, Baur C, Gargas ML, Filser JG.
    Toxicol Appl Pharmacol; 2000 May 15; 165(1):1-26. PubMed ID: 10814549
    [Abstract] [Full Text] [Related]

  • 7. Genotoxicity of 1,3-butadiene and its epoxy intermediates.
    Walker VE, Walker DM, Meng Q, McDonald JD, Scott BR, Seilkop SK, Claffey DJ, Upton PB, Powley MW, Swenberg JA, Henderson RF, Health Review Committee.
    Res Rep Health Eff Inst; 2009 Aug 15; (144):3-79. PubMed ID: 20017413
    [Abstract] [Full Text] [Related]

  • 8. A physiologically based toxicokinetic model for inhaled ethylene and ethylene oxide in mouse, rat, and human.
    Filser JG, Klein D.
    Toxicol Lett; 2018 Apr 15; 286():54-79. PubMed ID: 28774830
    [Abstract] [Full Text] [Related]

  • 9. An evaluation of concentrations of styrene-7,8-oxide in rats and humans resulting from exposure to styrene or styrene-7,8-oxide and potential genotoxicity.
    Filser JG, Gelbke HP.
    Toxicol Lett; 2016 Apr 15; 247():11-28. PubMed ID: 26851640
    [Abstract] [Full Text] [Related]

  • 10. A physiologic pharmacokinetic model for styrene and styrene-7,8-oxide in mouse, rat and man.
    Csanády GA, Mendrala AL, Nolan RJ, Filser JG.
    Arch Toxicol; 1994 Apr 15; 68(3):143-57. PubMed ID: 8024461
    [Abstract] [Full Text] [Related]

  • 11. In vitro kinetics of styrene and styrene oxide metabolism in rat, mouse, and human.
    Mendrala AL, Langvardt PW, Nitschke KD, Quast JF, Nolan RJ.
    Arch Toxicol; 1993 Apr 15; 67(1):18-27. PubMed ID: 8452475
    [Abstract] [Full Text] [Related]

  • 12. Physiologically based pharmacokinetic modeling of styrene and styrene oxide respiratory-tract dosimetry in rodents and humans.
    Sarangapani R, Teeguarden JG, Cruzan G, Clewell HJ, Andersen ME.
    Inhal Toxicol; 2002 Aug 15; 14(8):789-834. PubMed ID: 12122565
    [Abstract] [Full Text] [Related]

  • 13. Dosimetry by means of DNA and hemoglobin adducts in propylene oxide-exposed rats.
    Osterman-Golkar S, Czene K, Lee MS, Faller TH, Csanády GA, Kessler W, Pérez HL, Filser JG, Segerbäck D.
    Toxicol Appl Pharmacol; 2003 Sep 15; 191(3):245-54. PubMed ID: 13678657
    [Abstract] [Full Text] [Related]

  • 14. Dose responses for DNA adduct formation in tissues of rats and mice exposed by inhalation to low concentrations of 1,3-[2,3-[(14)C]-butadiene.
    Booth ED, Kilgour JD, Robinson SA, Watson WP.
    Chem Biol Interact; 2004 Mar 15; 147(2):195-211. PubMed ID: 15013821
    [Abstract] [Full Text] [Related]

  • 15. Effects of the structure of a toxicokinetic model of butadiene inhalation exposure on computed production of carcinogenic intermediates.
    Kohn MC, Melnick RL.
    Toxicology; 1996 Oct 28; 113(1-3):31-9. PubMed ID: 8901880
    [Abstract] [Full Text] [Related]

  • 16. PBPK model for butadiene metabolism to epoxides: quantitative species differences in metabolism.
    Johanson G, Filser JG.
    Toxicology; 1996 Oct 28; 113(1-3):40-7. PubMed ID: 8901881
    [Abstract] [Full Text] [Related]

  • 17. In vivo doses of butadiene epoxides as estimated from in vitro enzyme kinetics by using cob(I)alamin and measured hemoglobin adducts: an inter-species extrapolation approach.
    Motwani HV, Törnqvist M.
    Toxicol Appl Pharmacol; 2014 Dec 15; 281(3):276-84. PubMed ID: 25448046
    [Abstract] [Full Text] [Related]

  • 18. A physiologically based pharmacokinetic model for butadiene and its metabolite butadiene monoxide in rat and mouse and its significance for risk extrapolation.
    Johanson G, Filser JG.
    Arch Toxicol; 1993 Dec 15; 67(3):151-63. PubMed ID: 8494494
    [Abstract] [Full Text] [Related]

  • 19. A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans.
    Ramsey JC, Andersen ME.
    Toxicol Appl Pharmacol; 1984 Mar 30; 73(1):159-75. PubMed ID: 6710512
    [Abstract] [Full Text] [Related]

  • 20. The role of cytochromes P-450 in styrene induced pulmonary toxicity and carcinogenicity.
    Green T, Toghill A, Foster JR.
    Toxicology; 2001 Dec 14; 169(2):107-17. PubMed ID: 11718952
    [Abstract] [Full Text] [Related]

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