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Journal Abstract Search

280 related items for PubMed ID: 12572531

  • 1. Synthesis, antibacterial activity, and toxicity of 7-(isoindolin-5-yl)-4-oxoquinoline-3-carboxylic acids. Discovery of the novel des-F(6)-quinolone antibacterial agent garenoxacin (T-3811 or BMS-284756).
    Hayashi K, Takahata M, Kawamura Y, Todo Y.
    Arzneimittelforschung; 2002; 52(12):903-13. PubMed ID: 12572531
    [Abstract] [Full Text] [Related]

  • 2. Novel fluoroquinolone antibacterial agents containing oxime-substituted (aminomethyl)pyrrolidines: synthesis and antibacterial activity of 7-(4-(aminomethyl)-3-(methoxyimino)pyrrolidin-1-yl)-1-cyclopropyl-6- fluoro-4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxylic acid (LB20304).
    Hong CY, Kim YK, Chang JH, Kim SH, Choi H, Nam DH, Kim YZ, Kwak JH.
    J Med Chem; 1997 Oct 24; 40(22):3584-93. PubMed ID: 9357525
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis, and biological evaluations of novel 7-[7-amino-7-methyl-5-azaspiro[2.4]heptan-5-yl]-8-methoxyquinolines with potent antibacterial activity against respiratory pathogens.
    Odagiri T, Inagaki H, Sugimoto Y, Nagamochi M, Miyauchi RN, Kuroyanagi J, Kitamura T, Komoriya S, Takahashi H.
    J Med Chem; 2013 Mar 14; 56(5):1974-83. PubMed ID: 23409972
    [Abstract] [Full Text] [Related]

  • 4. [In vitro evaluation of lomefloxacin].
    Dette GA, Knothe H.
    Arzneimittelforschung; 1989 Aug 14; 39(8):832-5. PubMed ID: 2818672
    [Abstract] [Full Text] [Related]

  • 5. Comparative activity of garenoxacin and other agents by susceptibility and time-kill testing against Staphylococcus aureus, Streptococcus pyogenes and respiratory pathogens.
    Noviello S, Ianniello F, Leone S, Esposito S.
    J Antimicrob Chemother; 2003 Nov 14; 52(5):869-72. PubMed ID: 14519672
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and antibacterial activity of novel 6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-4-oxoquinoline-3-carboxylic acids bearing cyclopropane-fused 2-amino-8-azabicyclo[4.3.0]nonan-8-yl substituents at the C-7 position.
    Inagaki H, Takahashi H, Takemura M.
    Bioorg Med Chem Lett; 2004 Oct 18; 14(20):5193-8. PubMed ID: 15380226
    [Abstract] [Full Text] [Related]

  • 7. Activities of BMS 284756 (T-3811) against Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pneumoniae isolates from SENTRY antimicrobial surveillance program medical centers in Latin America (1999).
    Gales A, Sader H, Jones RN, SENTRY Participants Group (Latin America).
    Antimicrob Agents Chemother; 2001 May 18; 45(5):1463-6. PubMed ID: 11302811
    [Abstract] [Full Text] [Related]

  • 8. Studies on quinolone antibacterials. V. Synthesis and antibacterial activity of chiral 5-amino-7-(4-substituted-3-amino-1-pyrrolidinyl)-6- fluoro-1,4-dihydro-8-methyl-4-oxoquinoline-3-carboxylic acids and derivatives.
    Yoshida T, Yamamoto Y, Orita H, Kakiuchi M, Takahashi Y, Itakura M, Kado N, Yasuda S, Kato H, Itoh Y.
    Chem Pharm Bull (Tokyo); 1996 Jul 18; 44(7):1376-86. PubMed ID: 8706143
    [Abstract] [Full Text] [Related]

  • 9. [Studies on pyridonecarboxylic acids as antibacterial agents. XII. Synthesis and antibacterial activity of 6-chloro-1-cyclopropyl-7-(1-piperazinyl)-1, 4-dihydro-4-oxo-quinoline-3-carboxylic acid and analogues].
    Li XH, Tian ZM, Miao H, Yu LX, Guo HY.
    Yao Xue Xue Bao; 1997 Nov 18; 32(11):844-51. PubMed ID: 11596203
    [Abstract] [Full Text] [Related]

  • 10. [The history of the development and changes of quinolone antibacterial agents].
    Takahashi H, Hayakawa I, Akimoto T.
    Yakushigaku Zasshi; 2003 Nov 18; 38(2):161-79. PubMed ID: 15143768
    [Abstract] [Full Text] [Related]

  • 11. [Synthesis and antibacterial activity of 1-substituted benzyl quinolone acid derivatives].
    Zhou SQ, Zhu CQ, Wu GP, Peng SX.
    Yao Xue Xue Bao; 1990 Nov 18; 25(9):670-6. PubMed ID: 2128731
    [Abstract] [Full Text] [Related]

  • 12. 5-Amino-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6,8-difluoro-1,4- dihydro-4-oxo-3-quinolinecarboxylic acid (PD 124,816). Synthesis and biological evaluation of a new class of quinolone antibacterials.
    Domagala JM, Hagen SE, Hutt MP, Sanchez JP, Sesnie J, Trehan AK.
    Drugs Exp Clin Res; 1988 Nov 18; 14(7):453-60. PubMed ID: 2853667
    [Abstract] [Full Text] [Related]

  • 13. In vitro and in vivo antimicrobial activities of T-3811ME, a novel des-F(6)-quinolone.
    Takahata M, Mitsuyama J, Yamashiro Y, Yonezawa M, Araki H, Todo Y, Minami S, Watanabe Y, Narita H.
    Antimicrob Agents Chemother; 1999 May 18; 43(5):1077-84. PubMed ID: 10223917
    [Abstract] [Full Text] [Related]

  • 14. Activity of garenoxacin, an investigational des-F(6)-quinolone, tested against pathogens from community-acquired respiratory tract infections, including those with elevated or resistant-level fluoroquinolone MIC values.
    Jones RN, Fritsche TR, Sader HS, Stilwell MG.
    Diagn Microbiol Infect Dis; 2007 May 18; 58(1):9-17. PubMed ID: 17408903
    [Abstract] [Full Text] [Related]

  • 15. Therapeutic effect of the quinolone prodrug prulifloxacin against experimental urinary tract infections in mice.
    Tomii Y, Ozaki M, Matsuda M, Honmura T, Nishimura I, Yamaguchi R, Adachi T, Okawa Y, Nishino T.
    Arzneimittelforschung; 1996 Dec 18; 46(12):1169-73. PubMed ID: 9006794
    [Abstract] [Full Text] [Related]

  • 16. In vitro antibacterial activity of FA103, a new quinolone derivative of C-7 position with 7-perhydrodiazepinone.
    Imamori K, Asaoka T, Matsumoto M, Maebashi K, Matsuda H, Tahara Y.
    Jpn J Antibiot; 1995 Dec 18; 48(12):1891-8. PubMed ID: 8587163
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and antibacterial activity of 7-(1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-7-yl) quinolones.
    Zhu B, Marinelli BA, Goldschmidt R, Foleno BD, Hilliard JJ, Bush K, Macielag MJ.
    Bioorg Med Chem Lett; 2009 Sep 01; 19(17):4933-6. PubMed ID: 19646867
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and in vitro antibacterial activity of some N-(5-aryl-1,3,4-thiadiazole-2-yl)piperazinyl quinolone derivatives.
    Foroumadi A, Soltani F, Moshafi MH, Ashraf-Askari R.
    Farmaco; 2003 Oct 01; 58(10):1023-8. PubMed ID: 14505733
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and antibacterial activity of N-(5-benzylthio-1,3,4-thiadiazol-2-yl) and N-(5-benzylsulfonyl-1,3,4-thiadiazol-2-yl)piperazinyl quinolone derivatives.
    Foroumadi A, Emami S, Hassanzadeh A, Rajaee M, Sokhanvar K, Moshafi MH, Shafiee A.
    Bioorg Med Chem Lett; 2005 Oct 15; 15(20):4488-92. PubMed ID: 16105736
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and structure--antibacterial activity relationships of 7-(3-amino-1-propynyl and 3-amino-1-propenyl)quinolones.
    Fujita M, Chiba K, Nakano J, Tominaga Y, Matsumoto J.
    Chem Pharm Bull (Tokyo); 1998 Apr 15; 46(4):631-8. PubMed ID: 9579039
    [Abstract] [Full Text] [Related]

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