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Journal Abstract Search


314 related items for PubMed ID: 12579299

  • 1. Regulation of cell cycle progression and apoptosis by the Ras/Raf/MEK/ERK pathway (Review).
    Chang F, Steelman LS, Shelton JG, Lee JT, Navolanic PM, Blalock WL, Franklin R, McCubrey JA.
    Int J Oncol; 2003 Mar; 22(3):469-80. PubMed ID: 12579299
    [Abstract] [Full Text] [Related]

  • 2. Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma.
    Yang R, Piperdi S, Gorlick R.
    Clin Cancer Res; 2008 Oct 15; 14(20):6396-404. PubMed ID: 18927278
    [Abstract] [Full Text] [Related]

  • 3. Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines.
    Ulivi P, Arienti C, Amadori D, Fabbri F, Carloni S, Tesei A, Vannini I, Silvestrini R, Zoli W.
    J Cell Physiol; 2009 Jul 15; 220(1):214-21. PubMed ID: 19288493
    [Abstract] [Full Text] [Related]

  • 4. Opposite role of Ras in tumor necrosis factor-alpha-induced cell cycle regulation: competition for Raf kinase.
    Park SJ, Kim YY, Lim JY, Seo GJ, Kim J, Park SI, Park BJ.
    Biochem Biophys Res Commun; 2001 Oct 12; 287(5):1140-7. PubMed ID: 11587542
    [Abstract] [Full Text] [Related]

  • 5. Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions.
    Kolch W.
    Biochem J; 2000 Oct 15; 351 Pt 2(Pt 2):289-305. PubMed ID: 11023813
    [Abstract] [Full Text] [Related]

  • 6. Resistance to mitogen-activated protein kinase kinase (MEK) inhibitors correlates with up-regulation of the MEK/extracellular signal-regulated kinase pathway in hepatocellular carcinoma cells.
    Yip-Schneider MT, Klein PJ, Wentz SC, Zeni A, Menze A, Schmidt CM.
    J Pharmacol Exp Ther; 2009 Jun 15; 329(3):1063-70. PubMed ID: 19258520
    [Abstract] [Full Text] [Related]

  • 7. A-Raf and Raf-1 work together to influence transient ERK phosphorylation and Gl/S cell cycle progression.
    Mercer K, Giblett S, Oakden A, Brown J, Marais R, Pritchard C.
    Oncogene; 2005 Aug 04; 24(33):5207-17. PubMed ID: 15856007
    [Abstract] [Full Text] [Related]

  • 8. NBS1 is required for IGF-1 induced cellular proliferation through the Ras/Raf/MEK/ERK cascade.
    Hematulin A, Sagan D, Eckardt-Schupp F, Moertl S.
    Cell Signal; 2008 Dec 04; 20(12):2276-85. PubMed ID: 18793719
    [Abstract] [Full Text] [Related]

  • 9. Oridonin induces G2/M arrest and apoptosis via activating ERK-p53 apoptotic pathway and inhibiting PTK-Ras-Raf-JNK survival pathway in murine fibrosarcoma L929 cells.
    Cheng Y, Qiu F, Ye YC, Tashiro S, Onodera S, Ikejima T.
    Arch Biochem Biophys; 2009 Oct 01; 490(1):70-5. PubMed ID: 19699177
    [Abstract] [Full Text] [Related]

  • 10. Raf-1 kinase activation is uncoupled from downstream MEK/ERK pathway in cells treated with Src tyrosine kinase inhibitor PP2.
    Lee M.
    Biochem Biophys Res Commun; 2006 Nov 17; 350(2):450-6. PubMed ID: 17010316
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of the Raf-MEK1/2-ERK1/2 signaling pathway, Bcl-xL down-regulation, and chemosensitization of non-Hodgkin's lymphoma B cells by Rituximab.
    Jazirehi AR, Vega MI, Chatterjee D, Goodglick L, Bonavida B.
    Cancer Res; 2004 Oct 01; 64(19):7117-26. PubMed ID: 15466208
    [Abstract] [Full Text] [Related]

  • 12. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer.
    Roberts PJ, Der CJ.
    Oncogene; 2007 May 14; 26(22):3291-310. PubMed ID: 17496923
    [Abstract] [Full Text] [Related]

  • 13. Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf.
    Marzec M, Kasprzycka M, Liu X, Raghunath PN, Wlodarski P, Wasik MA.
    Oncogene; 2007 Feb 08; 26(6):813-21. PubMed ID: 16909118
    [Abstract] [Full Text] [Related]

  • 14. MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation.
    Chadee DN, Kyriakis JM.
    Nat Cell Biol; 2004 Aug 08; 6(8):770-6. PubMed ID: 15258589
    [Abstract] [Full Text] [Related]

  • 15. Neurotensin stimulates protein kinase C-dependent mitogenic signaling in human pancreatic carcinoma cell line PANC-1.
    Guha S, Lunn JA, Santiskulvong C, Rozengurt E.
    Cancer Res; 2003 May 15; 63(10):2379-87. PubMed ID: 12750255
    [Abstract] [Full Text] [Related]

  • 16. Enhancement of peripheral benzodiazepine receptor ligand-induced apoptosis and cell cycle arrest of esophageal cancer cells by simultaneous inhibition of MAPK/ERK kinase.
    Sutter AP, Maaser K, Gerst B, Krahn A, Zeitz M, Scherübl H.
    Biochem Pharmacol; 2004 May 01; 67(9):1701-10. PubMed ID: 15081869
    [Abstract] [Full Text] [Related]

  • 17. Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1.
    Sasaki A, Taketomi T, Kato R, Saeki K, Nonami A, Sasaki M, Kuriyama M, Saito N, Shibuya M, Yoshimura A.
    Nat Cell Biol; 2003 May 01; 5(5):427-32. PubMed ID: 12717443
    [Abstract] [Full Text] [Related]

  • 18. Activated Raf inhibits avian myogenesis through a MAPK-dependent mechanism.
    Dorman CM, Johnson SE.
    Oncogene; 1999 Sep 16; 18(37):5167-76. PubMed ID: 10498866
    [Abstract] [Full Text] [Related]

  • 19. Constitutive activation of the Raf-MAPK pathway causes negative feedback inhibition of Ras-PI3K-AKT and cellular arrest through the EphA2 receptor.
    Menges CW, McCance DJ.
    Oncogene; 2008 May 01; 27(20):2934-40. PubMed ID: 18059341
    [Abstract] [Full Text] [Related]

  • 20. Flagellin and lipopolysaccharide stimulate the MEK-ERK signaling pathway in chicken heterophils through differential activation of the small GTPases, Ras and Rap1.
    Kogut MH, Genovese KJ, He H.
    Mol Immunol; 2007 Mar 01; 44(7):1729-36. PubMed ID: 17045653
    [Abstract] [Full Text] [Related]


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