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136 related items for PubMed ID: 12588866

  • 1. Non-steroidal anti-inflammatory drugs inhibit nitric oxide-induced apoptosis and dedifferentiation of articular chondrocytes independent of cyclooxygenase activity.
    Yoon JB, Kim SJ, Hwang SG, Chang S, Kang SS, Chun JS.
    J Biol Chem; 2003 Apr 25; 278(17):15319-25. PubMed ID: 12588866
    [Abstract] [Full Text] [Related]

  • 2. p38 kinase-dependent and -independent Inhibition of protein kinase C zeta and -alpha regulates nitric oxide-induced apoptosis and dedifferentiation of articular chondrocytes.
    Kim SJ, Kim HG, Oh CD, Hwang SG, Song WK, Yoo YJ, Kang SS, Chun JS.
    J Biol Chem; 2002 Aug 16; 277(33):30375-81. PubMed ID: 12048219
    [Abstract] [Full Text] [Related]

  • 3. Actin cytoskeletal architecture regulates nitric oxide-induced apoptosis, dedifferentiation, and cyclooxygenase-2 expression in articular chondrocytes via mitogen-activated protein kinase and protein kinase C pathways.
    Kim SJ, Hwang SG, Kim IC, Chun JS.
    J Biol Chem; 2003 Oct 24; 278(43):42448-56. PubMed ID: 12907684
    [Abstract] [Full Text] [Related]

  • 4. ERK-1/2 and p38 kinase oppositely regulate nitric oxide-induced apoptosis of chondrocytes in association with p53, caspase-3, and differentiation status.
    Kim SJ, Ju JW, Oh CD, Yoon YM, Song WK, Kim JH, Yoo YJ, Bang OS, Kang SS, Chun JS.
    J Biol Chem; 2002 Jan 11; 277(2):1332-9. PubMed ID: 11689560
    [Abstract] [Full Text] [Related]

  • 5. Protein kinase C alpha and zeta regulate nitric oxide-induced NF-kappa B activation that mediates cyclooxygenase-2 expression and apoptosis but not dedifferentiation in articular chondrocytes.
    Kim SJ, Chun JS.
    Biochem Biophys Res Commun; 2003 Mar 28; 303(1):206-11. PubMed ID: 12646188
    [Abstract] [Full Text] [Related]

  • 6. ERK-1/-2 and p38 kinase oppositely regulate 15-deoxy-delta(12,14)-prostaglandinJ(2)-Induced PPAR-gamma activation that mediates dedifferentiation but not cyclooxygenase-2 expression in articular chondrocytes.
    Yoon EK, Lee WK, Lee JH, Yu SM, Hwang SG, Kim SJ.
    J Korean Med Sci; 2007 Dec 28; 22(6):1015-21. PubMed ID: 18162716
    [Abstract] [Full Text] [Related]

  • 7. Differentiation status-dependent regulation of cyclooxygenase-2 expression and prostaglandin E2 production by epidermal growth factor via mitogen-activated protein kinase in articular chondrocytes.
    Huh YH, Kim SH, Kim SJ, Chun JS.
    J Biol Chem; 2003 Mar 14; 278(11):9691-7. PubMed ID: 12493746
    [Abstract] [Full Text] [Related]

  • 8. Signaling mechanisms leading to the regulation of differentiation and apoptosis of articular chondrocytes by insulin-like growth factor-1.
    Oh CD, Chun JS.
    J Biol Chem; 2003 Sep 19; 278(38):36563-71. PubMed ID: 12853454
    [Abstract] [Full Text] [Related]

  • 9. Hyaluronic acid inhibits nitric oxide-induced apoptosis and dedifferentiation of articular chondrocytes in vitro.
    Peng H, Zhou JL, Liu SQ, Hu QJ, Ming JH, Qiu B.
    Inflamm Res; 2010 Jul 19; 59(7):519-30. PubMed ID: 20077126
    [Abstract] [Full Text] [Related]

  • 10. p38 kinase mediates nitric oxide-induced apoptosis of chondrocytes through the inhibition of protein kinase C zeta by blocking autophosphorylation.
    Kim JS, Park ZY, Yoo YJ, Yu SS, Chun JS.
    Cell Death Differ; 2005 Mar 19; 12(3):201-12. PubMed ID: 15665819
    [Abstract] [Full Text] [Related]

  • 11. Maintenance of differentiated phenotype of articular chondrocytes by protein kinase C and extracellular signal-regulated protein kinase.
    Yoon YM, Kim SJ, Oh CD, Ju JW, Song WK, Yoo YJ, Huh TL, Chun JS.
    J Biol Chem; 2002 Mar 08; 277(10):8412-20. PubMed ID: 11744731
    [Abstract] [Full Text] [Related]

  • 12. Cytokine-induced apoptosis inhibitor-1 causes dedifferentiation of rabbit articular chondrocytes via the ERK-1/2 and p38 kinase pathways.
    Yu SM, Yeo HJ, Choi SY, Kim SJ.
    Int J Biochem Cell Biol; 2016 Nov 08; 80():10-18. PubMed ID: 27644154
    [Abstract] [Full Text] [Related]

  • 13. PEP-1-SIRT2 causes dedifferentiation and COX-2 expression via the MAPK pathways in rabbit articular chondrocytes.
    Eo SH, Kim DW, Choi SY, Kim HA, Kim SJ.
    Exp Cell Res; 2015 Dec 10; 339(2):351-9. PubMed ID: 26358233
    [Abstract] [Full Text] [Related]

  • 14. p38 kinase regulates nitric oxide-induced apoptosis of articular chondrocytes by accumulating p53 via NFkappa B-dependent transcription and stabilization by serine 15 phosphorylation.
    Kim SJ, Hwang SG, Shin DY, Kang SS, Chun JS.
    J Biol Chem; 2002 Sep 06; 277(36):33501-8. PubMed ID: 12091386
    [Abstract] [Full Text] [Related]

  • 15. Differentiation regulates interleukin-1beta-induced cyclo-oxygenase-2 in human articular chondrocytes: role of p38 mitogen-activated protein kinase.
    Thomas B, Thirion S, Humbert L, Tan L, Goldring MB, Béréziat G, Berenbaum F.
    Biochem J; 2002 Mar 01; 362(Pt 2):367-73. PubMed ID: 11853544
    [Abstract] [Full Text] [Related]

  • 16. The thymoquinone-induced production of reactive oxygen species promotes dedifferentiation through the ERK pathway and inflammation through the p38 and PI3K pathways in rabbit articular chondrocytes.
    Yu SM, Kim SJ.
    Int J Mol Med; 2015 Feb 01; 35(2):325-32. PubMed ID: 25435376
    [Abstract] [Full Text] [Related]

  • 17. Apoptosis induced by NO via phosphorylation of p38 MAPK that stimulates NF-kappaB, p53 and caspase-3 activation in rabbit articular chondrocytes.
    Wang H, Wang Z, Chen J, Wu J.
    Cell Biol Int; 2007 Sep 01; 31(9):1027-35. PubMed ID: 17468017
    [Abstract] [Full Text] [Related]

  • 18. PEP-1-glutaredoxin-1 induces dedifferentiation of rabbit articular chondrocytes by the endoplasmic reticulum stress-dependent ERK-1/2 pathway and the endoplasmic reticulum stress-independent p38 kinase and PI-3 kinase pathways.
    Yu SM, Choi YJ, Kim SJ.
    Int J Biol Macromol; 2018 May 01; 111():1059-1066. PubMed ID: 29366902
    [Abstract] [Full Text] [Related]

  • 19. Chondrocyte death in experimental osteoarthritis is mediated by MEK 1/2 and p38 pathways: role of cyclooxygenase-2 and inducible nitric oxide synthase.
    Pelletier JP, Fernandes JC, Jovanovic DV, Reboul P, Martel-Pelletier J.
    J Rheumatol; 2001 Nov 01; 28(11):2509-19. PubMed ID: 11708426
    [Abstract] [Full Text] [Related]

  • 20. c-Jun/activator protein-1 mediates interleukin-1beta-induced dedifferentiation but not cyclooxygenase-2 expression in articular chondrocytes.
    Hwang SG, Yu SS, Poo H, Chun JS.
    J Biol Chem; 2005 Aug 19; 280(33):29780-7. PubMed ID: 15961395
    [Abstract] [Full Text] [Related]

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