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263 related items for PubMed ID: 12592338

  • 1. Constitutively active Akt1 protects HL60 leukemia cells from TRAIL-induced apoptosis through a mechanism involving NF-kappaB activation and cFLIP(L) up-regulation.
    Bortul R, Tazzari PL, Cappellini A, Tabellini G, Billi AM, Bareggi R, Manzoli L, Cocco L, Martelli AM.
    Leukemia; 2003 Feb; 17(2):379-89. PubMed ID: 12592338
    [Abstract] [Full Text] [Related]

  • 2. Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer.
    Chen X, Thakkar H, Tyan F, Gim S, Robinson H, Lee C, Pandey SK, Nwokorie C, Onwudiwe N, Srivastava RK.
    Oncogene; 2001 Sep 20; 20(42):6073-83. PubMed ID: 11593415
    [Abstract] [Full Text] [Related]

  • 3. A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells.
    Martelli AM, Tazzari PL, Tabellini G, Bortul R, Billi AM, Manzoli L, Ruggeri A, Conte R, Cocco L.
    Leukemia; 2003 Sep 20; 17(9):1794-805. PubMed ID: 12970779
    [Abstract] [Full Text] [Related]

  • 4. Phosphoinositide 3-kinase/Akt involvement in arsenic trioxide resistance of human leukemia cells.
    Tabellini G, Cappellini A, Tazzari PL, Falà F, Billi AM, Manzoli L, Cocco L, Martelli AM.
    J Cell Physiol; 2005 Feb 20; 202(2):623-34. PubMed ID: 15316930
    [Abstract] [Full Text] [Related]

  • 5. Serum bioactive lysophospholipids prevent TRAIL-induced apoptosis via PI3K/Akt-dependent cFLIP expression and Bad phosphorylation.
    Kang YC, Kim KM, Lee KS, Namkoong S, Lee SJ, Han JA, Jeoung D, Ha KS, Kwon YG, Kim YM.
    Cell Death Differ; 2004 Dec 20; 11(12):1287-98. PubMed ID: 15297884
    [Abstract] [Full Text] [Related]

  • 6. Sensitization of tumor cells to Apo2 ligand/TRAIL-induced apoptosis by inhibition of casein kinase II.
    Ravi R, Bedi A.
    Cancer Res; 2002 Aug 01; 62(15):4180-5. PubMed ID: 12154014
    [Abstract] [Full Text] [Related]

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  • 9. TRAIL-induced apoptosis in human vascular endothelium is regulated by phosphatidylinositol 3-kinase/Akt through the short form of cellular FLIP and Bcl-2.
    Alladina SJ, Song JH, Davidge ST, Hao C, Easton AS.
    J Vasc Res; 2005 Aug 01; 42(4):337-47. PubMed ID: 15985761
    [Abstract] [Full Text] [Related]

  • 10. Role of the phosphatidylinositol 3'-kinase/PTEN/Akt kinase pathway in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in non-small cell lung cancer cells.
    Kandasamy K, Srivastava RK.
    Cancer Res; 2002 Sep 01; 62(17):4929-37. PubMed ID: 12208743
    [Abstract] [Full Text] [Related]

  • 11. Akt protects mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis through NK-kappa B activation.
    Hatano E, Brenner DA.
    Am J Physiol Gastrointest Liver Physiol; 2001 Dec 01; 281(6):G1357-68. PubMed ID: 11705740
    [Abstract] [Full Text] [Related]

  • 12. PI-3K/Akt and NF-kappaB/IkappaBalpha pathways are activated in Jurkat T cells in response to TRAIL treatment.
    Zauli G, Sancilio S, Cataldi A, Sabatini N, Bosco D, Di Pietro R.
    J Cell Physiol; 2005 Mar 01; 202(3):900-11. PubMed ID: 15389633
    [Abstract] [Full Text] [Related]

  • 13. Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications.
    Mitsiades CS, Mitsiades N, Poulaki V, Schlossman R, Akiyama M, Chauhan D, Hideshima T, Treon SP, Munshi NC, Richardson PG, Anderson KC.
    Oncogene; 2002 Aug 22; 21(37):5673-83. PubMed ID: 12173037
    [Abstract] [Full Text] [Related]

  • 14. Caspase-8 activation is necessary but not sufficient for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in the prostatic carcinoma cell line LNCaP.
    Rokhlin OW, Guseva NV, Tagiyev AF, Glover RA, Cohen MB.
    Prostate; 2002 Jun 01; 52(1):1-11. PubMed ID: 11992615
    [Abstract] [Full Text] [Related]

  • 15. cFLIPL inhibits tumor necrosis factor-related apoptosis-inducing ligand-mediated NF-kappaB activation at the death-inducing signaling complex in human keratinocytes.
    Wachter T, Sprick M, Hausmann D, Kerstan A, McPherson K, Stassi G, Bröcker EB, Walczak H, Leverkus M.
    J Biol Chem; 2004 Dec 17; 279(51):52824-34. PubMed ID: 15459191
    [Abstract] [Full Text] [Related]

  • 16. Selective targeting of the nuclear factor-kappaB pathway enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated pancreatic cancer cell death.
    Thomas RP, Farrow BJ, Kim S, May MJ, Hellmich MR, Evers BM.
    Surgery; 2002 Aug 17; 132(2):127-34. PubMed ID: 12219002
    [Abstract] [Full Text] [Related]

  • 17. Mechanisms of resistance to TRAIL-induced apoptosis in cancer.
    Zhang L, Fang B.
    Cancer Gene Ther; 2005 Mar 17; 12(3):228-37. PubMed ID: 15550937
    [Abstract] [Full Text] [Related]

  • 18. NF-kappa B does not modulate sensitivity of renal carcinoma cells to TNF alpha-related apoptosis-inducing ligand (TRAIL).
    Pawlowski JE, Nesterov A, Scheinman RI, Johnson TR, Kraft AS.
    Anticancer Res; 2000 Mar 17; 20(6B):4243-55. PubMed ID: 11205254
    [Abstract] [Full Text] [Related]

  • 19. NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling.
    Kreuz S, Siegmund D, Scheurich P, Wajant H.
    Mol Cell Biol; 2001 Jun 17; 21(12):3964-73. PubMed ID: 11359904
    [Abstract] [Full Text] [Related]

  • 20. Regulation of tumor necrosis factor-related apoptosis-inducing ligand sensitivity in primary and transformed human keratinocytes.
    Leverkus M, Neumann M, Mengling T, Rauch CT, Bröcker EB, Krammer PH, Walczak H.
    Cancer Res; 2000 Feb 01; 60(3):553-9. PubMed ID: 10676636
    [Abstract] [Full Text] [Related]

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