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169 related items for PubMed ID: 12594834

  • 1. Concerted action of perforin and granzymes is critical for the elimination of Trypanosoma cruzi from mouse tissues, but prevention of early host death is in addition dependent on the FasL/Fas pathway.
    Müller U, Sobek V, Balkow S, Hölscher C, Müllbacher A, Museteanu C, Mossmann H, Simon MM.
    Eur J Immunol; 2003 Jan; 33(1):70-8. PubMed ID: 12594834
    [Abstract] [Full Text] [Related]

  • 2. Independent roles of perforin, granzymes, and Fas in the control of Friend retrovirus infection.
    Zelinskyy G, Balkow S, Schimmer S, Schepers K, Simon MM, Dittmer U.
    Virology; 2004 Dec 20; 330(2):365-74. PubMed ID: 15567431
    [Abstract] [Full Text] [Related]

  • 3. Antigen-induced cell death of T effector cells in vitro proceeds via the Fas pathway, requires endogenous interferon-gamma and is independent of perforin and granzymes.
    Sobek V, Balkow S, Körner H, Simon MM.
    Eur J Immunol; 2002 Sep 20; 32(9):2490-9. PubMed ID: 12207333
    [Abstract] [Full Text] [Related]

  • 4. Perforin and Fas act together in the induction of apoptosis, and both are critical in the clearance of lymphocytic choriomeningitis virus infection.
    Rode M, Balkow S, Sobek V, Brehm R, Martin P, Kersten A, Dumrese T, Stehle T, Müllbacher A, Wallich R, Simon MM.
    J Virol; 2004 Nov 20; 78(22):12395-405. PubMed ID: 15507626
    [Abstract] [Full Text] [Related]

  • 5. Control of murine cytomegalovirus replication in salivary glands during acute infection is independent of the Fas ligand/Fas system.
    Riera L, Gariglio M, Pagano M, Gaiola O, Simon MM, Landolfo S.
    New Microbiol; 2001 Jul 20; 24(3):231-8. PubMed ID: 11497079
    [Abstract] [Full Text] [Related]

  • 6. Comparing the relative role of perforin/granzyme versus Fas/Fas ligand cytotoxic pathways in CD8+ T cell-mediated insulin-dependent diabetes mellitus.
    Kreuwel HT, Morgan DJ, Krahl T, Ko A, Sarvetnick N, Sherman LA.
    J Immunol; 1999 Oct 15; 163(8):4335-41. PubMed ID: 10510373
    [Abstract] [Full Text] [Related]

  • 7. Dimethyl 2,2-dichlorovinyl phosphate (DDVP) markedly inhibits activities of natural killer cells, cytotoxic T lymphocytes and lymphokine-activated killer cells via the Fas-ligand/Fas pathway in perforin-knockout (PKO) mice.
    Li Q, Nakadai A, Takeda K, Kawada T.
    Toxicology; 2004 Nov 01; 204(1):41-50. PubMed ID: 15369847
    [Abstract] [Full Text] [Related]

  • 8. In vivo rejection of tumor cells dependent on CD8 cells that kill independently of perforin and FasL.
    Lee SH, Bar-Haim E, Machlenkin A, Goldberger O, Volovitz I, Vadai E, Tzehoval E, Eisenbach L.
    Cancer Gene Ther; 2004 Mar 01; 11(3):237-48. PubMed ID: 14739939
    [Abstract] [Full Text] [Related]

  • 9. Acquisition of granzyme B and Fas ligand proteins by human keratinocytes contributes to epidermal cell defense.
    Berthou C, Michel L, Soulié A, Jean-Louis F, Flageul B, Dubertret L, Sigaux F, Zhang Y, Sasportes M.
    J Immunol; 1997 Dec 01; 159(11):5293-300. PubMed ID: 9548468
    [Abstract] [Full Text] [Related]

  • 10. Fas-mediated cytotoxicity remains intact in perforin and granzyme B antisense transfectants of a human NK-like cell line.
    Montel AH, Bochan MR, Goebel WS, Brahmi Z.
    Cell Immunol; 1995 Oct 15; 165(2):312-7. PubMed ID: 7553897
    [Abstract] [Full Text] [Related]

  • 11. Upregulation of two death pathways of perforin/granzyme and FasL/Fas in septic acute respiratory distress syndrome.
    Hashimoto S, Kobayashi A, Kooguchi K, Kitamura Y, Onodera H, Nakajima H.
    Am J Respir Crit Care Med; 2000 Jan 15; 161(1):237-43. PubMed ID: 10619826
    [Abstract] [Full Text] [Related]

  • 12. A critical role for granzyme B, in addition to perforin and TNFalpha, in alloreactive CTL-induced mouse pancreatic beta cell death.
    Sutton VR, Estella E, Li C, Chen M, Thomas HE, Kay TW, Trapani JA.
    Transplantation; 2006 Jan 27; 81(2):146-54. PubMed ID: 16436955
    [Abstract] [Full Text] [Related]

  • 13. Fas- and tumor necrosis factor receptor 1-dependent but not perforin-dependent pathways cause injury in livers infected with an adenovirus construct in mice.
    Liu ZX, Govindarajan S, Okamoto S, Dennert G.
    Hepatology; 2000 Mar 27; 31(3):665-73. PubMed ID: 10706557
    [Abstract] [Full Text] [Related]

  • 14. The level of friend retrovirus replication determines the cytolytic pathway of CD8+ T-cell-mediated pathogen control.
    Zelinskyy G, Balkow S, Schimmer S, Werner T, Simon MM, Dittmer U.
    J Virol; 2007 Nov 27; 81(21):11881-90. PubMed ID: 17728236
    [Abstract] [Full Text] [Related]

  • 15. Fas and perforin are not required for thymus atrophy induced by Trypanosoma cruzi infection.
    Henriques-Pons A, DeMeis J, Cotta-De-Almeida V, Savino W, Araújo-Jorge TC.
    Exp Parasitol; 2004 Nov 27; 107(1-2):1-4. PubMed ID: 15208031
    [Abstract] [Full Text] [Related]

  • 16. Effector cells derived from host CD8 memory T cells mediate rapid resistance against minor histocompatibility antigen-mismatched allogeneic marrow grafts without participation of perforin, Fas ligand, and the simultaneous inhibition of 3 tumor necrosis factor family effector pathways.
    Zimmerman Z, Shatry A, Deyev V, Podack E, Mammolenti M, Blazar BR, Yagita H, Levy RB.
    Biol Blood Marrow Transplant; 2005 Aug 27; 11(8):576-86. PubMed ID: 16041307
    [Abstract] [Full Text] [Related]

  • 17. Bcl-2 prevents apoptosis induced by perforin and granzyme B, but not that mediated by whole cytotoxic lymphocytes.
    Sutton VR, Vaux DL, Trapani JA.
    J Immunol; 1997 Jun 15; 158(12):5783-90. PubMed ID: 9190929
    [Abstract] [Full Text] [Related]

  • 18. Perforin and granzyme B of cytotoxic T lymphocyte mediate apoptosis irrespective of Helicobacter pylori infection: possible act as a trigger of peptic ulcer formation.
    Ohara T, Morishita T, Suzuki H, Masaoka T, Ishii H.
    Hepatogastroenterology; 2003 Jun 15; 50(54):1774-9. PubMed ID: 14696402
    [Abstract] [Full Text] [Related]

  • 19. Concerted action of the FasL/Fas and perforin/granzyme A and B pathways is mandatory for the development of early viral hepatitis but not for recovery from viral infection.
    Balkow S, Kersten A, Tran TT, Stehle T, Grosse P, Museteanu C, Utermöhlen O, Pircher H, von Weizsäcker F, Wallich R, Müllbacher A, Simon MM.
    J Virol; 2001 Sep 15; 75(18):8781-91. PubMed ID: 11507223
    [Abstract] [Full Text] [Related]

  • 20. Granzymes are essential for natural killer cell-mediated and perf-facilitated tumor control.
    Pardo J, Balkow S, Anel A, Simon MM.
    Eur J Immunol; 2002 Oct 15; 32(10):2881-7. PubMed ID: 12355441
    [Abstract] [Full Text] [Related]

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