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245 related items for PubMed ID: 12598647
1. Type I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesis. Cheng YQ, Tang GL, Shen B. Proc Natl Acad Sci U S A; 2003 Mar 18; 100(6):3149-54. PubMed ID: 12598647 [Abstract] [Full Text] [Related]
5. C-S bond cleavage by a polyketide synthase domain. Ma M, Lohman JR, Liu T, Shen B. Proc Natl Acad Sci U S A; 2015 Aug 18; 112(33):10359-64. PubMed ID: 26240335 [Abstract] [Full Text] [Related]
7. The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase. Du L, Sánchez C, Chen M, Edwards DJ, Shen B. Chem Biol; 2000 Aug 18; 7(8):623-42. PubMed ID: 11048953 [Abstract] [Full Text] [Related]
9. Characterization of the Ketosynthase and Acyl Carrier Protein Domains at the LnmI Nonribosomal Peptide Synthetase-Polyketide Synthase Interface for Leinamycin Biosynthesis. Huang Y, Tang GL, Pan G, Chang CY, Shen B. Org Lett; 2016 Sep 02; 18(17):4288-91. PubMed ID: 27541042 [Abstract] [Full Text] [Related]
10. P450-Catalyzed Tailoring Steps in Leinamycin Biosynthesis Featuring Regio- and Stereoselective Hydroxylations and Substrate Promiscuities. Kwong T, Ma M, Pan G, Hindra, Yang D, Yang C, Lohman JR, Rudolf JD, Cleveland JL, Shen B. Biochemistry; 2018 Aug 21; 57(33):5005-5013. PubMed ID: 30070831 [Abstract] [Full Text] [Related]
12. Cloning, sequencing and analysis of the enterocin biosynthesis gene cluster from the marine isolate 'Streptomyces maritimus': evidence for the derailment of an aromatic polyketide synthase. Piel J, Hertweck C, Shipley PR, Hunt DM, Newman MS, Moore BS. Chem Biol; 2000 Dec 21; 7(12):943-55. PubMed ID: 11137817 [Abstract] [Full Text] [Related]
13. Characterization of the enzymatic domains in the modular polyketide synthase involved in rifamycin B biosynthesis by Amycolatopsis mediterranei. Tang L, Yoon YJ, Choi CY, Hutchinson CR. Gene; 1998 Aug 31; 216(2):255-65. PubMed ID: 9729415 [Abstract] [Full Text] [Related]
14. Chain initiation in the leinamycin-producing hybrid nonribosomal peptide/polyketide synthetase from Streptomyces atroolivaceus S-140. Discrete, monofunctional adenylation enzyme and peptidyl carrier protein that directly load D-alanine. Tang GL, Cheng YQ, Shen B. J Biol Chem; 2007 Jul 13; 282(28):20273-82. PubMed ID: 17502372 [Abstract] [Full Text] [Related]
17. Characterization of LnmO as a pathway-specific Crp/Fnr-type positive regulator for leinamycin biosynthesis in Streptomyces atroolivaceus and its application for titer improvement. Huang Y, Yang D, Pan G, Tang GL, Shen B. Appl Microbiol Biotechnol; 2016 Dec 13; 100(24):10555-10562. PubMed ID: 27704182 [Abstract] [Full Text] [Related]
18. Dissecting the role of acyltransferase domains of modular polyketide synthases in the choice and stereochemical fate of extender units. Lau J, Fu H, Cane DE, Khosla C. Biochemistry; 1999 Feb 02; 38(5):1643-51. PubMed ID: 9931032 [Abstract] [Full Text] [Related]
19. Mechanisms of molecular recognition in the pikromycin polyketide synthase. Chen S, Xue Y, Sherman DH, Reynolds KA. Chem Biol; 2000 Dec 02; 7(12):907-18. PubMed ID: 11137814 [Abstract] [Full Text] [Related]
20. Polyketide synthase acyl carrier protein (ACP) as a substrate and a catalyst for malonyl ACP biosynthesis. Zhou P, Florova G, Reynolds KA. Chem Biol; 1999 Aug 02; 6(8):577-84. PubMed ID: 10421763 [Abstract] [Full Text] [Related] Page: [Next] [New Search]