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171 related items for PubMed ID: 12604126

  • 1. The role of a Runt domain transcription factor AML1/RUNX1 in leukemogenesis and its clinical implications.
    Asou N.
    Crit Rev Oncol Hematol; 2003 Feb; 45(2):129-50. PubMed ID: 12604126
    [Abstract] [Full Text] [Related]

  • 2. Rearrangement of the AML1/CBFA2 gene in myeloid leukemia with the 3;21 translocation: expression of co-existing multiple chimeric genes with similar functions as transcriptional repressors, but with opposite tumorigenic properties.
    Zent C, Kim N, Hiebert S, Zhang DE, Tenen DG, Rowley JD, Nucifora G.
    Curr Top Microbiol Immunol; 1996 Feb; 211():243-52. PubMed ID: 8585955
    [Abstract] [Full Text] [Related]

  • 3. The AML1/ETO(MTG8) and AML1/Evi-1 leukemia-associated chimeric oncoproteins accumulate PEBP2beta(CBFbeta) in the nucleus more efficiently than wild-type AML1.
    Tanaka K, Tanaka T, Kurokawa M, Imai Y, Ogawa S, Mitani K, Yazaki Y, Hirai H.
    Blood; 1998 Mar 01; 91(5):1688-99. PubMed ID: 9473235
    [Abstract] [Full Text] [Related]

  • 4. New mechanisms of AML1 gene alteration in hematological malignancies.
    Roumier C, Fenaux P, Lafage M, Imbert M, Eclache V, Preudhomme C.
    Leukemia; 2003 Jan 01; 17(1):9-16. PubMed ID: 12529654
    [Abstract] [Full Text] [Related]

  • 5. The AML1 gene: a transcription factor involved in the pathogenesis of myeloid and lymphoid leukemias.
    Lo Coco F, Pisegna S, Diverio D.
    Haematologica; 1997 Jan 01; 82(3):364-70. PubMed ID: 9234595
    [Abstract] [Full Text] [Related]

  • 6. High incidence of biallelic point mutations in the Runt domain of the AML1/PEBP2 alpha B gene in Mo acute myeloid leukemia and in myeloid malignancies with acquired trisomy 21.
    Preudhomme C, Warot-Loze D, Roumier C, Grardel-Duflos N, Garand R, Lai JL, Dastugue N, Macintyre E, Denis C, Bauters F, Kerckaert JP, Cosson A, Fenaux P.
    Blood; 2000 Oct 15; 96(8):2862-9. PubMed ID: 11023523
    [Abstract] [Full Text] [Related]

  • 7. Rearrangements of the AML1/CBFA2 gene in myeloid leukemia with the 3;21 translocation: in vitro and in vivo studies.
    Zent C, Rowley JD, Nucifora G.
    Leukemia; 1997 Apr 15; 11 Suppl 3():273-8. PubMed ID: 9209363
    [Abstract] [Full Text] [Related]

  • 8. Implications of somatic mutations in the AML1 gene in radiation-associated and therapy-related myelodysplastic syndrome/acute myeloid leukemia.
    Harada H, Harada Y, Tanaka H, Kimura A, Inaba T.
    Blood; 2003 Jan 15; 101(2):673-80. PubMed ID: 12393679
    [Abstract] [Full Text] [Related]

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  • 10. Runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1 transgene advances a model for studies of leukemogenesis.
    Kalev-Zylinska ML, Horsfield JA, Flores MV, Postlethwait JH, Vitas MR, Baas AM, Crosier PS, Crosier KE.
    Development; 2002 Apr 15; 129(8):2015-30. PubMed ID: 11934867
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  • 12. High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia.
    Harada H, Harada Y, Niimi H, Kyo T, Kimura A, Inaba T.
    Blood; 2004 Mar 15; 103(6):2316-24. PubMed ID: 14615365
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  • 14. AML1 interconnected pathways of leukemogenesis.
    Michaud J, Scott HS, Escher R.
    Cancer Invest; 2003 Mar 15; 21(1):105-36. PubMed ID: 12643014
    [Abstract] [Full Text] [Related]

  • 15. AML1/RUNX1 mutations are infrequent, but related to AML-M0, acquired trisomy 21, and leukemic transformation in pediatric hematologic malignancies.
    Taketani T, Taki T, Takita J, Tsuchida M, Hanada R, Hongo T, Kaneko T, Manabe A, Ida K, Hayashi Y.
    Genes Chromosomes Cancer; 2003 Sep 15; 38(1):1-7. PubMed ID: 12874780
    [Abstract] [Full Text] [Related]

  • 16. siRNA-mediated AML1/MTG8 depletion affects differentiation and proliferation-associated gene expression in t(8;21)-positive cell lines and primary AML blasts.
    Dunne J, Cullmann C, Ritter M, Soria NM, Drescher B, Debernardi S, Skoulakis S, Hartmann O, Krause M, Krauter J, Neubauer A, Young BD, Heidenreich O.
    Oncogene; 2006 Oct 05; 25(45):6067-78. PubMed ID: 16652140
    [Abstract] [Full Text] [Related]

  • 17. Dual functions of the AML1/Evi-1 chimeric protein in the mechanism of leukemogenesis in t(3;21) leukemias.
    Tanaka T, Mitani K, Kurokawa M, Ogawa S, Tanaka K, Nishida J, Yazaki Y, Shibata Y, Hirai H.
    Mol Cell Biol; 1995 May 05; 15(5):2383-92. PubMed ID: 7739522
    [Abstract] [Full Text] [Related]

  • 18. Novel loss-of-function mutations of the haematopoiesis-related transcription factor, acute myeloid leukaemia 1/runt-related transcription factor 1, detected in acute myeloblastic leukaemia and myelodysplastic syndrome.
    Nakao M, Horiike S, Fukushima-Nakase Y, Nishimura M, Fujita Y, Taniwaki M, Okuda T.
    Br J Haematol; 2004 Jun 05; 125(6):709-19. PubMed ID: 15180860
    [Abstract] [Full Text] [Related]

  • 19. Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia.
    Higuchi M, O'Brien D, Kumaravelu P, Lenny N, Yeoh EJ, Downing JR.
    Cancer Cell; 2002 Feb 05; 1(1):63-74. PubMed ID: 12086889
    [Abstract] [Full Text] [Related]

  • 20. Role of the transcription factor AML-1 in acute leukemia and hematopoietic differentiation.
    Lutterbach B, Hiebert SW.
    Gene; 2000 Mar 21; 245(2):223-35. PubMed ID: 10717473
    [Abstract] [Full Text] [Related]

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