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117 related items for PubMed ID: 12604232
1. Stereochemical aspects of carbonyl reduction of the original anticancer drug oracin by mouse liver microsomes and purified 11beta-hydroxysteroid dehydrogenase type 1. Wsól V, Szotáková B, Skálová L, Maser E. Chem Biol Interact; 2003 Feb 01; 143-144():459-68. PubMed ID: 12604232 [Abstract] [Full Text] [Related]
2. The novel anticancer drug oracin: different stereospecificity and cooperativity for carbonyl reduction by purified human liver 11beta-hydroxysteroid dehydrogenase type 1. Wsól V, Szotáková B, Skálová L, Maser E. Toxicology; 2004 May 03; 197(3):253-61. PubMed ID: 15033547 [Abstract] [Full Text] [Related]
3. Partial purification and characterization of a new human membrane-bound carbonyl reductase playing a role in the deactivation of the anticancer drug oracin. Skarydová L, Skarka A, Novotná R, Zivná L, Martin HJ, Wsól V, Maser E. Toxicology; 2009 Oct 01; 264(1-2):52-60. PubMed ID: 19635524 [Abstract] [Full Text] [Related]
5. Reduction of the potential anticancer drug oracin in the rat liver in-vitro. Szotáková B, Skálová L, Wsól V, Kvasniècková E. J Pharm Pharmacol; 2000 May 01; 52(5):495-500. PubMed ID: 10864136 [Abstract] [Full Text] [Related]
6. A comparison between stereospecificity of oracin reduction and stereoselectivity of oxidation of 11-dihydrooracin enantiomers in vitro in rat and guinea pig. Skálová L, Wsól V, Szotáková B, Kvasnicková E. Chirality; 1999 May 01; 11(5-6):510-5. PubMed ID: 10368925 [Abstract] [Full Text] [Related]
7. Stereospecific reduction of the original anticancer drug oracin in rat extrahepatic tissues. Szotáková B, Skálová L, Jílek P, Buchta V, Wsól V. J Pharm Pharmacol; 2003 Jul 01; 55(7):1003-11. PubMed ID: 12906758 [Abstract] [Full Text] [Related]
8. 11Beta-hydroxysteroid dehydrogenase responsible for carbonyl reduction of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes. Maser E. Cancer Res; 1998 Jul 15; 58(14):2996-3003. PubMed ID: 9679962 [Abstract] [Full Text] [Related]
10. The main metabolic pathway of oracin, a new potential cytostatic drug, in human liver microsomes and cytosol: stereoselectivity of reoxidation of the principal metabolite 11-dihydrooracin to oracin. Wsól V, Szotáková B, Skálová L, Cepková H, Kvasnicková E. Enantiomer; 2000 Jul 15; 5(3-4):263-70. PubMed ID: 11126866 [Abstract] [Full Text] [Related]
12. Purification, characterization and NNK carbonyl reductase activities of 11beta-hydroxysteroid dehydrogenase type 1 from human liver: enzyme cooperativity and significance in the detoxification of a tobacco-derived carcinogen. Maser E, Friebertshäuser J, Völker B. Chem Biol Interact; 2003 Feb 01; 143-144():435-48. PubMed ID: 12604230 [Abstract] [Full Text] [Related]
14. 11 Beta-hydroxysteroid dehydrogenase type 1 from human liver: dimerization and enzyme cooperativity support its postulated role as glucocorticoid reductase. Maser E, Völker B, Friebertshäuser J. Biochemistry; 2002 Feb 19; 41(7):2459-65. PubMed ID: 11841241 [Abstract] [Full Text] [Related]
15. Heterogeneity of 11beta-hydroxysteroid dehydrogenase type 1/microsomal carbonyl reductase (11beta-HSD/CR) in guinea pig tissues. Purification of the liver form suggests modification in the cosubstrate binding site. Oppermann UC, Möbus E, Nagel G, Maser E. Toxicology; 2000 Apr 03; 144(1-3):63-9. PubMed ID: 10781872 [Abstract] [Full Text] [Related]
17. In the search for specific inhibitors of human 11beta-hydroxysteroid-dehydrogenases (11beta-HSDs): chenodeoxycholic acid selectively inhibits 11beta-HSD-I. Diederich S, Grossmann C, Hanke B, Quinkler M, Herrmann M, Bähr V, Oelkers W. Eur J Endocrinol; 2000 Feb 03; 142(2):200-7. PubMed ID: 10664531 [Abstract] [Full Text] [Related]
20. Carbonyl reduction of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in cytosol of mouse liver and lung. Atalla A, Maser E. Toxicology; 1999 Nov 29; 139(1-2):155-66. PubMed ID: 10614696 [Abstract] [Full Text] [Related] Page: [Next] [New Search]