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Journal Abstract Search

181 related items for PubMed ID: 12604685

  • 1. Distribution of STI-571 to the brain is limited by P-glycoprotein-mediated efflux.
    Dai H, Marbach P, Lemaire M, Hayes M, Elmquist WF.
    J Pharmacol Exp Ther; 2003 Mar; 304(3):1085-92. PubMed ID: 12604685
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  • 3. P-glycoprotein efflux at the blood-brain barrier mediates differences in brain disposition and pharmacodynamics between two structurally related neurokinin-1 receptor antagonists.
    Smith BJ, Doran AC, McLean S, Tingley FD, O'Neill BT, Kajiji SM.
    J Pharmacol Exp Ther; 2001 Sep; 298(3):1252-9. PubMed ID: 11504828
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  • 4. In vitro P-glycoprotein assays to predict the in vivo interactions of P-glycoprotein with drugs in the central nervous system.
    Feng B, Mills JB, Davidson RE, Mireles RJ, Janiszewski JS, Troutman MD, de Morais SM.
    Drug Metab Dispos; 2008 Feb; 36(2):268-75. PubMed ID: 17962372
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  • 5. Blonanserin, a novel atypical antipsychotic agent not actively transported as substrate by P-glycoprotein.
    Inoue T, Osada K, Tagawa M, Ogawa Y, Haga T, Sogame Y, Hashizume T, Watanabe T, Taguchi A, Katsumata T, Yabuki M, Yamaguchi N.
    Prog Neuropsychopharmacol Biol Psychiatry; 2012 Oct 01; 39(1):156-62. PubMed ID: 22691713
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  • 6. P-glycoprotein-mediated active efflux of the anti-HIV1 nucleoside abacavir limits cellular accumulation and brain distribution.
    Shaik N, Giri N, Pan G, Elmquist WF.
    Drug Metab Dispos; 2007 Nov 01; 35(11):2076-85. PubMed ID: 17709369
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  • 7. Pharmacokinetics and pharmacodynamics of alfentanil in P-glycoprotein-competent and P-glycoprotein-deficient mice: P-glycoprotein efflux alters alfentanil brain disposition and antinociception.
    Kalvass JC, Olson ER, Pollack GM.
    Drug Metab Dispos; 2007 Mar 01; 35(3):455-9. PubMed ID: 17178769
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  • 9. The disposition of saquinavir in normal and P-glycoprotein deficient mice, rats, and in cultured cells.
    Washington CB, Wiltshire HR, Man M, Moy T, Harris SR, Worth E, Weigl P, Liang Z, Hall D, Marriott L, Blaschke TF.
    Drug Metab Dispos; 2000 Sep 01; 28(9):1058-62. PubMed ID: 10950849
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  • 10. Role of P-glycoprotein and the intestine in the excretion of DPC 333 [(2R)-2-{(3R)-3-amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in rodents.
    Garner CE, Solon E, Lai CM, Lin J, Luo G, Jones K, Duan J, Decicco CP, Maduskuie T, Mercer SE, Gan LS, Qian M, Prakash S, Shen HS, Lee FW.
    Drug Metab Dispos; 2008 Jun 01; 36(6):1102-10. PubMed ID: 18347085
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  • 12. Complete in vivo reversal of P-glycoprotein pump function in the blood-brain barrier visualized with positron emission tomography.
    Hendrikse NH, Schinkel AH, de Vries EG, Fluks E, Van der Graaf WT, Willemsen AT, Vaalburg W, Franssen EJ.
    Br J Pharmacol; 1998 Aug 01; 124(7):1413-8. PubMed ID: 9723952
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  • 13. The influence of the P-glycoprotein inhibitor zosuquidar trihydrochloride (LY335979) on the brain penetration of paclitaxel in mice.
    Kemper EM, Cleypool C, Boogerd W, Beijnen JH, van Tellingen O.
    Cancer Chemother Pharmacol; 2004 Feb 01; 53(2):173-8. PubMed ID: 14605863
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  • 14. P-glycoprotein reduces the ability of amitriptyline metabolites to cross the blood brain barrier in mice after a 10-day administration of amitriptyline.
    Grauer MT, Uhr M.
    J Psychopharmacol; 2004 Mar 01; 18(1):66-74. PubMed ID: 15107187
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  • 15. Species comparison of in vivo P-glycoprotein-mediated brain efflux using mdr1a-deficient rats and mice.
    Bundgaard C, Jensen CJ, Garmer M.
    Drug Metab Dispos; 2012 Mar 01; 40(3):461-6. PubMed ID: 22112383
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  • 17. Differential involvement of multidrug resistance-associated protein 1 and P-glycoprotein in tissue distribution and excretion of grepafloxacin in mice.
    Sasabe H, Kato Y, Suzuki T, Itose M, Miyamoto G, Sugiyama Y.
    J Pharmacol Exp Ther; 2004 Aug 01; 310(2):648-55. PubMed ID: 15131241
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  • 18. P-glycoprotein plays a major role in the efflux of fexofenadine in the small intestine and blood-brain barrier, but only a limited role in its biliary excretion.
    Tahara H, Kusuhara H, Fuse E, Sugiyama Y.
    Drug Metab Dispos; 2005 Jul 01; 33(7):963-8. PubMed ID: 15821041
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  • 19. Comparison of drug efflux transport kinetics in various blood-brain barrier models.
    Bachmeier CJ, Trickler WJ, Miller DW.
    Drug Metab Dispos; 2006 Jun 01; 34(6):998-1003. PubMed ID: 16554372
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  • 20. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2- Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration.
    Liu H, Yu N, Lu S, Ito S, Zhang X, Prasad B, He E, Lu X, Li Y, Wang F, Xu H, An G, Unadkat JD, Kusuhara H, Sugiyama Y, Sahi J.
    Drug Metab Dispos; 2015 Jul 01; 43(7):1008-18. PubMed ID: 25908246
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