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Journal Abstract Search


537 related items for PubMed ID: 12606543

  • 21. Hypoxia-inducible factor-2α stabilizes the von Hippel-Lindau (VHL) disease suppressor, Myb-related protein 2.
    Okumura F, Joo-Okumura A, Nakatsukasa K, Kamura T.
    PLoS One; 2017; 12(4):e0175593. PubMed ID: 28394947
    [Abstract] [Full Text] [Related]

  • 22. Von Hippel-Lindau tumor suppressor protein and hypoxia-inducible factor in kidney cancer.
    Maynard MA, Ohh M.
    Am J Nephrol; 2004; 24(1):1-13. PubMed ID: 14654728
    [Abstract] [Full Text] [Related]

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  • 25. Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex.
    Maynard MA, Qi H, Chung J, Lee EH, Kondo Y, Hara S, Conaway RC, Conaway JW, Ohh M.
    J Biol Chem; 2003 Mar 28; 278(13):11032-40. PubMed ID: 12538644
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  • 27. Nur77 activated by hypoxia-inducible factor-1alpha overproduces proopiomelanocortin in von Hippel-Lindau-mutated renal cell carcinoma.
    Choi JW, Park SC, Kang GH, Liu JO, Youn HD.
    Cancer Res; 2004 Jan 01; 64(1):35-9. PubMed ID: 14729605
    [Abstract] [Full Text] [Related]

  • 28. The VHL protein recruits a novel KRAB-A domain protein to repress HIF-1alpha transcriptional activity.
    Li Z, Wang D, Na X, Schoen SR, Messing EM, Wu G.
    EMBO J; 2003 Apr 15; 22(8):1857-67. PubMed ID: 12682018
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  • 29. Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein.
    Ohh M, Park CW, Ivan M, Hoffman MA, Kim TY, Huang LE, Pavletich N, Chau V, Kaelin WG.
    Nat Cell Biol; 2000 Jul 15; 2(7):423-7. PubMed ID: 10878807
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  • 31. Proline hydroxylation at different sites in hypoxia-inducible factor 1α modulates its interactions with the von Hippel-Lindau tumor suppressor protein.
    Qian H, Zou Y, Tang Y, Gong Y, Qian Z, Wei G, Zhang Q.
    Phys Chem Chem Phys; 2018 Jul 11; 20(27):18756-18765. PubMed ID: 29961792
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  • 32. Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1alpha through activation of mitogen-activated protein kinase pathway.
    Yoo YG, Oh SH, Park ES, Cho H, Lee N, Park H, Kim DK, Yu DY, Seong JK, Lee MO.
    J Biol Chem; 2003 Oct 03; 278(40):39076-84. PubMed ID: 12855680
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  • 33. PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation.
    Zhou J, Schmid T, Frank R, Brüne B.
    J Biol Chem; 2004 Apr 02; 279(14):13506-13. PubMed ID: 14726529
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  • 34. Insulin and hypoxia share common target genes but not the hypoxia-inducible factor-1alpha.
    Yim S, Choi SM, Choi Y, Lee N, Chung J, Park H.
    J Biol Chem; 2003 Oct 03; 278(40):38260-8. PubMed ID: 12876287
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  • 35. Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway.
    Isaacs JS, Jung YJ, Mimnaugh EG, Martinez A, Cuttitta F, Neckers LM.
    J Biol Chem; 2002 Aug 16; 277(33):29936-44. PubMed ID: 12052835
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  • 36. Leu-574 of HIF-1alpha is essential for the von Hippel-Lindau (VHL)-mediated degradation pathway.
    Huang LE, Pete EA, Schau M, Milligan J, Gu J.
    J Biol Chem; 2002 Nov 01; 277(44):41750-5. PubMed ID: 12205091
    [Abstract] [Full Text] [Related]

  • 37. HIF-1alpha and EPAS ubiquitination mediated by the VHL tumour suppressor involves flexibility in the ubiquitination mechanism, similar to other RING E3 ligases.
    Paltoglou S, Roberts BJ.
    Oncogene; 2007 Jan 25; 26(4):604-9. PubMed ID: 16862177
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  • 38. The pVHL-associated SCF ubiquitin ligase complex: molecular genetic analysis of elongin B and C, Rbx1 and HIF-1alpha in renal cell carcinoma.
    Clifford SC, Astuti D, Hooper L, Maxwell PH, Ratcliffe PJ, Maher ER.
    Oncogene; 2001 Aug 16; 20(36):5067-74. PubMed ID: 11526493
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  • 39. RNF4 and VHL regulate the proteasomal degradation of SUMO-conjugated Hypoxia-Inducible Factor-2alpha.
    van Hagen M, Overmeer RM, Abolvardi SS, Vertegaal AC.
    Nucleic Acids Res; 2010 Apr 16; 38(6):1922-31. PubMed ID: 20026589
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  • 40. HIF hydroxylation and the mammalian oxygen-sensing pathway.
    Safran M, Kaelin WG.
    J Clin Invest; 2003 Mar 16; 111(6):779-83. PubMed ID: 12639980
    [No Abstract] [Full Text] [Related]


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