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537 related items for PubMed ID: 12606543
21. Hypoxia-inducible factor-2α stabilizes the von Hippel-Lindau (VHL) disease suppressor, Myb-related protein 2. Okumura F, Joo-Okumura A, Nakatsukasa K, Kamura T. PLoS One; 2017; 12(4):e0175593. PubMed ID: 28394947 [Abstract] [Full Text] [Related]
22. Von Hippel-Lindau tumor suppressor protein and hypoxia-inducible factor in kidney cancer. Maynard MA, Ohh M. Am J Nephrol; 2004; 24(1):1-13. PubMed ID: 14654728 [Abstract] [Full Text] [Related]
25. Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex. Maynard MA, Qi H, Chung J, Lee EH, Kondo Y, Hara S, Conaway RC, Conaway JW, Ohh M. J Biol Chem; 2003 Mar 28; 278(13):11032-40. PubMed ID: 12538644 [Abstract] [Full Text] [Related]
27. Nur77 activated by hypoxia-inducible factor-1alpha overproduces proopiomelanocortin in von Hippel-Lindau-mutated renal cell carcinoma. Choi JW, Park SC, Kang GH, Liu JO, Youn HD. Cancer Res; 2004 Jan 01; 64(1):35-9. PubMed ID: 14729605 [Abstract] [Full Text] [Related]
28. The VHL protein recruits a novel KRAB-A domain protein to repress HIF-1alpha transcriptional activity. Li Z, Wang D, Na X, Schoen SR, Messing EM, Wu G. EMBO J; 2003 Apr 15; 22(8):1857-67. PubMed ID: 12682018 [Abstract] [Full Text] [Related]
29. Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein. Ohh M, Park CW, Ivan M, Hoffman MA, Kim TY, Huang LE, Pavletich N, Chau V, Kaelin WG. Nat Cell Biol; 2000 Jul 15; 2(7):423-7. PubMed ID: 10878807 [Abstract] [Full Text] [Related]
31. Proline hydroxylation at different sites in hypoxia-inducible factor 1α modulates its interactions with the von Hippel-Lindau tumor suppressor protein. Qian H, Zou Y, Tang Y, Gong Y, Qian Z, Wei G, Zhang Q. Phys Chem Chem Phys; 2018 Jul 11; 20(27):18756-18765. PubMed ID: 29961792 [Abstract] [Full Text] [Related]
32. Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1alpha through activation of mitogen-activated protein kinase pathway. Yoo YG, Oh SH, Park ES, Cho H, Lee N, Park H, Kim DK, Yu DY, Seong JK, Lee MO. J Biol Chem; 2003 Oct 03; 278(40):39076-84. PubMed ID: 12855680 [Abstract] [Full Text] [Related]
33. PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation. Zhou J, Schmid T, Frank R, Brüne B. J Biol Chem; 2004 Apr 02; 279(14):13506-13. PubMed ID: 14726529 [Abstract] [Full Text] [Related]
34. Insulin and hypoxia share common target genes but not the hypoxia-inducible factor-1alpha. Yim S, Choi SM, Choi Y, Lee N, Chung J, Park H. J Biol Chem; 2003 Oct 03; 278(40):38260-8. PubMed ID: 12876287 [Abstract] [Full Text] [Related]
35. Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway. Isaacs JS, Jung YJ, Mimnaugh EG, Martinez A, Cuttitta F, Neckers LM. J Biol Chem; 2002 Aug 16; 277(33):29936-44. PubMed ID: 12052835 [Abstract] [Full Text] [Related]
36. Leu-574 of HIF-1alpha is essential for the von Hippel-Lindau (VHL)-mediated degradation pathway. Huang LE, Pete EA, Schau M, Milligan J, Gu J. J Biol Chem; 2002 Nov 01; 277(44):41750-5. PubMed ID: 12205091 [Abstract] [Full Text] [Related]
37. HIF-1alpha and EPAS ubiquitination mediated by the VHL tumour suppressor involves flexibility in the ubiquitination mechanism, similar to other RING E3 ligases. Paltoglou S, Roberts BJ. Oncogene; 2007 Jan 25; 26(4):604-9. PubMed ID: 16862177 [Abstract] [Full Text] [Related]
38. The pVHL-associated SCF ubiquitin ligase complex: molecular genetic analysis of elongin B and C, Rbx1 and HIF-1alpha in renal cell carcinoma. Clifford SC, Astuti D, Hooper L, Maxwell PH, Ratcliffe PJ, Maher ER. Oncogene; 2001 Aug 16; 20(36):5067-74. PubMed ID: 11526493 [Abstract] [Full Text] [Related]
39. RNF4 and VHL regulate the proteasomal degradation of SUMO-conjugated Hypoxia-Inducible Factor-2alpha. van Hagen M, Overmeer RM, Abolvardi SS, Vertegaal AC. Nucleic Acids Res; 2010 Apr 16; 38(6):1922-31. PubMed ID: 20026589 [Abstract] [Full Text] [Related]
40. HIF hydroxylation and the mammalian oxygen-sensing pathway. Safran M, Kaelin WG. J Clin Invest; 2003 Mar 16; 111(6):779-83. PubMed ID: 12639980 [No Abstract] [Full Text] [Related] Page: [Previous] [Next] [New Search]