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Journal Abstract Search

516 related items for PubMed ID: 12606603

  • 21. Histamine homologues discriminating between two functional H3 receptor assays. Evidence for H3 receptor heterogeneity?
    Leurs R, Kathmann M, Vollinga RC, Menge WM, Schlicker E, Timmerman H.
    J Pharmacol Exp Ther; 1996 Mar; 276(3):1009-15. PubMed ID: 8786529
    [Abstract] [Full Text] [Related]

  • 22. Use of an inverse agonist radioligand [3H]A-317920 reveals distinct pharmacological profiles of the rat histamine H3 receptor.
    Yao BB, Witte DG, Miller TR, Carr TL, Kang CH, Cassar S, Faghih R, Bennani YL, Surber BW, Hancock AA, Esbenshade TA.
    Neuropharmacology; 2006 Mar; 50(4):468-78. PubMed ID: 16316670
    [Abstract] [Full Text] [Related]

  • 23. 4-(omega-(alkyloxy)alkyl)-1H-imidazole derivatives as histamine H(3) receptor antagonists/agonists.
    Meier G, Krause M, Hüls A, Ligneau X, Pertz HH, Arrang JM, Ganellin CR, Schwartz JC, Schunack W, Stark H.
    J Med Chem; 2004 May 06; 47(10):2678-87. PubMed ID: 15115409
    [Abstract] [Full Text] [Related]

  • 24. Identification and pharmacological characterization of a series of new 1H-4-substituted-imidazoyl histamine H3 receptor ligands.
    Yates SL, Phillips JG, Gregory R, Pawlowski GP, Fadnis L, Khan MA, Ali SM, Tedford CE.
    J Pharmacol Exp Ther; 1999 May 06; 289(2):1151-9. PubMed ID: 10215699
    [Abstract] [Full Text] [Related]

  • 25. Ligands of the histamine H3-receptor: new potent antagonists of the 2-thioimidazole type.
    Plazzi PV, Mor M, Bordi F, Silva C, Rivara S, Caretta A, Ballabeni V, Impicciatore M, Vitali T.
    Farmaco; 1997 May 06; 52(5):295-302. PubMed ID: 9274000
    [Abstract] [Full Text] [Related]

  • 26. Autoregulation of McA-RH7777 hepatoma cell proliferation by histamine H3 receptors.
    Davenas E, Rouleau A, Morisset S, Arrang JM.
    J Pharmacol Exp Ther; 2008 Aug 06; 326(2):406-13. PubMed ID: 18474684
    [Abstract] [Full Text] [Related]

  • 27. An 80-amino acid deletion in the third intracellular loop of a naturally occurring human histamine H3 isoform confers pharmacological differences and constitutive activity.
    Bongers G, Krueger KM, Miller TR, Baranowski JL, Estvander BR, Witte DG, Strakhova MI, van Meer P, Bakker RA, Cowart MD, Hancock AA, Esbenshade TA, Leurs R.
    J Pharmacol Exp Ther; 2007 Dec 06; 323(3):888-98. PubMed ID: 17855474
    [Abstract] [Full Text] [Related]

  • 28. Development of chiral N-alkylcarbamates as new leads for potent and selective H3-receptor antagonists: synthesis, capillary electrophoresis, and in vitro and oral in vivo activity.
    Sasse A, Kiec-Kononowicz K, Stark H, Motyl M, Reidemeister S, Ganellin CR, Ligneau X, Schwartz JC, Schunack W.
    J Med Chem; 1999 Feb 25; 42(4):593-600. PubMed ID: 10052966
    [Abstract] [Full Text] [Related]

  • 29. Novel nonimidazole histamine H3 receptor antagonists: 1-(4-(phenoxymethyl)benzyl)piperidines and related compounds.
    Mikó T, Ligneau X, Pertz HH, Ganellin CR, Arrang JM, Schwartz JC, Schunack W, Stark H.
    J Med Chem; 2003 Apr 10; 46(8):1523-30. PubMed ID: 12672253
    [Abstract] [Full Text] [Related]

  • 30. Structurally novel histamine H3 receptor antagonists GSK207040 and GSK334429 improve scopolamine-induced memory impairment and capsaicin-induced secondary allodynia in rats.
    Medhurst AD, Briggs MA, Bruton G, Calver AR, Chessell I, Crook B, Davis JB, Davis RP, Foley AG, Heslop T, Hirst WD, Medhurst SJ, Ociepka S, Ray A, Regan CM, Sargent B, Schogger J, Stean TO, Trail BK, Upton N, White T, Orlek B, Wilson DM.
    Biochem Pharmacol; 2007 Apr 15; 73(8):1182-94. PubMed ID: 17276409
    [Abstract] [Full Text] [Related]

  • 31. Detailed pharmacological characterization of GT-2331 for the rat histamine H3 receptor.
    Ito S, Yoshimoto R, Miyamoto Y, Mitobe Y, Nakamura T, Ishihara A, MacNeil DJ, Kanatani A, Tokita S.
    Eur J Pharmacol; 2006 Jan 04; 529(1-3):40-6. PubMed ID: 16316645
    [Abstract] [Full Text] [Related]

  • 32. Structural variations of 1-(4-(phenoxymethyl)benzyl)piperidines as nonimidazole histamine H3 receptor antagonists.
    Mikó T, Ligneau X, Pertz HH, Arrang JM, Ganellin CR, Schwartz JC, Schunack W, Stark H.
    Bioorg Med Chem; 2004 May 15; 12(10):2727-36. PubMed ID: 15110854
    [Abstract] [Full Text] [Related]

  • 33. Antiobesity effects of A-331440, a novel non-imidazole histamine H3 receptor antagonist.
    Hancock AA, Bennani YL, Bush EN, Esbenshade TA, Faghih R, Fox GB, Jacobson P, Knourek-Segel V, Krueger KM, Nuss ME, Pan JB, Shapiro R, Witte DG, Yao BB.
    Eur J Pharmacol; 2004 Mar 08; 487(1-3):183-97. PubMed ID: 15033391
    [Abstract] [Full Text] [Related]

  • 34. In vitro profile of the antidepressant candidate OPC-14523 at rat and human 5-HT1A receptors.
    Jordan S, Chen R, Koprivica V, Hamilton R, Whitehead RE, Tottori K, Kikuchi T.
    Eur J Pharmacol; 2005 Jul 11; 517(3):165-73. PubMed ID: 15985260
    [Abstract] [Full Text] [Related]

  • 35. Native rat hippocampal 5-HT1A receptors show constitutive activity.
    Martel JC, Ormière AM, Leduc N, Assié MB, Cussac D, Newman-Tancredi A.
    Mol Pharmacol; 2007 Mar 11; 71(3):638-43. PubMed ID: 17167032
    [Abstract] [Full Text] [Related]

  • 36. Lack of cataleptogenic potentiation with non-imidazole H3 receptor antagonists reveals potential drug-drug interactions between imidazole-based H3 receptor antagonists and antipsychotic drugs.
    Zhang M, Ballard ME, Pan L, Roberts S, Faghih R, Cowart M, Esbenshade TA, Fox GB, Decker MW, Hancock AA, Rueter LE.
    Brain Res; 2005 May 31; 1045(1-2):142-9. PubMed ID: 15910772
    [Abstract] [Full Text] [Related]

  • 37. Constitutive activity of histamine h(3) receptors stably expressed in SK-N-MC cells: display of agonism and inverse agonism by H(3) antagonists.
    Wieland K, Bongers G, Yamamoto Y, Hashimoto T, Yamatodani A, Menge WM, Timmerman H, Lovenberg TW, Leurs R.
    J Pharmacol Exp Ther; 2001 Dec 31; 299(3):908-14. PubMed ID: 11714875
    [Abstract] [Full Text] [Related]

  • 38. Synthesis and in vitro pharmacology of a series of new chiral histamine H3-receptor ligands: 2-(R and S)-Amino-3-(1H-imidazol-4(5)-yl)propyl ether derivatives.
    Kovalainen JT, Christiaans JA, Kotisaari S, Laitinen JT, Männistö PT, Tuomisto L, Gynther J.
    J Med Chem; 1999 Apr 08; 42(7):1193-202. PubMed ID: 10197963
    [Abstract] [Full Text] [Related]

  • 39. Search for novel leads for histamine H3-receptor antagonists: oxygen-containing derivatives.
    Stark H, Hüls A, Ligneau X, Arrang JM, Schwartz JC, Schunack W.
    Pharmazie; 1997 Jul 08; 52(7):495-500. PubMed ID: 9266588
    [Abstract] [Full Text] [Related]

  • 40. Development of trans-2-[1H-imidazol-4-yl] cyclopropane derivatives as new high-affinity histamine H3 receptor ligands.
    Tedford CE, Phillips JG, Gregory R, Pawlowski GP, Fadnis L, Khan MA, Ali SM, Handley MK, Yates SL.
    J Pharmacol Exp Ther; 1999 May 08; 289(2):1160-8. PubMed ID: 10215700
    [Abstract] [Full Text] [Related]

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