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207 related items for PubMed ID: 12615712

  • 1. Wild-type p53 regulates human ribonucleotide reductase by protein-protein interaction with p53R2 as well as hRRM2 subunits.
    Xue L, Zhou B, Liu X, Qiu W, Jin Z, Yen Y.
    Cancer Res; 2003 Mar 01; 63(5):980-6. PubMed ID: 12615712
    [Abstract] [Full Text] [Related]

  • 2. The human ribonucleotide reductase subunit hRRM2 complements p53R2 in response to UV-induced DNA repair in cells with mutant p53.
    Zhou B, Liu X, Mo X, Xue L, Darwish D, Qiu W, Shih J, Hwu EB, Luh F, Yen Y.
    Cancer Res; 2003 Oct 15; 63(20):6583-94. PubMed ID: 14583450
    [Abstract] [Full Text] [Related]

  • 3. Characterization of enzymatic properties of human ribonucleotide reductase holoenzyme reconstituted in vitro from hRRM1, hRRM2, and p53R2 subunits.
    Qiu W, Zhou B, Darwish D, Shao J, Yen Y.
    Biochem Biophys Res Commun; 2006 Feb 10; 340(2):428-34. PubMed ID: 16376858
    [Abstract] [Full Text] [Related]

  • 4. In vitro characterization of enzymatic properties and inhibition of the p53R2 subunit of human ribonucleotide reductase.
    Shao J, Zhou B, Zhu L, Qiu W, Yuan YC, Xi B, Yen Y.
    Cancer Res; 2004 Jan 01; 64(1):1-6. PubMed ID: 14729598
    [Abstract] [Full Text] [Related]

  • 5. Ribonucleotide reductase subunits M2 and p53R2 are potential biomarkers for metastasis of colon cancer.
    Liu X, Zhou B, Xue L, Yen F, Chu P, Un F, Yen Y.
    Clin Colorectal Cancer; 2007 Jan 01; 6(5):374-81. PubMed ID: 17311703
    [Abstract] [Full Text] [Related]

  • 6. Determination of the potency and subunit-selectivity of ribonucleotide reductase inhibitors with a recombinant-holoenzyme-based in vitro assay.
    Shao J, Zhou B, Zhu L, Bilio AJ, Su L, Yuan YC, Ren S, Lien EJ, Shih J, Yen Y.
    Biochem Pharmacol; 2005 Feb 15; 69(4):627-34. PubMed ID: 15670581
    [Abstract] [Full Text] [Related]

  • 7. Expression status of ribonucleotide reductase small subunits hRRM2/p53R2 as prognostic biomarkers in stage I and II non-small cell lung cancer.
    Hsu NY, Wu JY, Liu X, Yen Y, Chen CY, Chou MC, Lin CH, Lee H, Cheng YW.
    Anticancer Res; 2011 Oct 15; 31(10):3475-81. PubMed ID: 21965764
    [Abstract] [Full Text] [Related]

  • 8. Metastasis-suppressing potential of ribonucleotide reductase small subunit p53R2 in human cancer cells.
    Liu X, Zhou B, Xue L, Shih J, Tye K, Lin W, Qi C, Chu P, Un F, Wen W, Yen Y.
    Clin Cancer Res; 2006 Nov 01; 12(21):6337-44. PubMed ID: 17085643
    [Abstract] [Full Text] [Related]

  • 9. Redox property of ribonucleotide reductase small subunit M2 and p53R2.
    Liu X, Xue L, Yen Y.
    Methods Mol Biol; 2008 Nov 01; 477():195-206. PubMed ID: 19082948
    [Abstract] [Full Text] [Related]

  • 10. Ribonucleotide reductase small subunit p53R2 facilitates p21 induction of G1 arrest under UV irradiation.
    Xue L, Zhou B, Liu X, Heung Y, Chau J, Chu E, Li S, Jiang C, Un F, Yen Y.
    Cancer Res; 2007 Jan 01; 67(1):16-21. PubMed ID: 17210678
    [Abstract] [Full Text] [Related]

  • 11. Structurally dependent redox property of ribonucleotide reductase subunit p53R2.
    Xue L, Zhou B, Liu X, Wang T, Shih J, Qi C, Heung Y, Yen Y.
    Cancer Res; 2006 Feb 15; 66(4):1900-5. PubMed ID: 16488986
    [Abstract] [Full Text] [Related]

  • 12. p53R2-dependent pathway for DNA synthesis in a p53-regulated cell cycle checkpoint.
    Yamaguchi T, Matsuda K, Sagiya Y, Iwadate M, Fujino MA, Nakamura Y, Arakawa H.
    Cancer Res; 2001 Nov 15; 61(22):8256-62. PubMed ID: 11719458
    [Abstract] [Full Text] [Related]

  • 13. A Ferrous-Triapine complex mediates formation of reactive oxygen species that inactivate human ribonucleotide reductase.
    Shao J, Zhou B, Di Bilio AJ, Zhu L, Wang T, Qi C, Shih J, Yen Y.
    Mol Cancer Ther; 2006 Mar 15; 5(3):586-92. PubMed ID: 16546972
    [Abstract] [Full Text] [Related]

  • 14. Expression and mutation analyses of P53R2, a newly identified p53 target for DNA repair in human gastric carcinoma.
    Byun DS, Chae KS, Ryu BK, Lee MG, Chi SG.
    Int J Cancer; 2002 Apr 10; 98(5):718-23. PubMed ID: 11920641
    [Abstract] [Full Text] [Related]

  • 15. 2.6 A X-ray crystal structure of human p53R2, a p53-inducible ribonucleotide reductase .
    Smith P, Zhou B, Ho N, Yuan YC, Su L, Tsai SC, Yen Y.
    Biochemistry; 2009 Nov 24; 48(46):11134-41. PubMed ID: 19728742
    [Abstract] [Full Text] [Related]

  • 16. p53R2 regulates thioredoxin reductase activity through interaction with TrxR2.
    Park SJ, Kim HB, Piao C, Kang MY, Park SG, Kim SW, Lee JH.
    Biochem Biophys Res Commun; 2017 Jan 22; 482(4):706-712. PubMed ID: 27866984
    [Abstract] [Full Text] [Related]

  • 17. Bcl2 induces DNA replication stress by inhibiting ribonucleotide reductase.
    Xie M, Yen Y, Owonikoko TK, Ramalingam SS, Khuri FR, Curran WJ, Doetsch PW, Deng X.
    Cancer Res; 2014 Jan 01; 74(1):212-23. PubMed ID: 24197132
    [Abstract] [Full Text] [Related]

  • 18. A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage.
    Tanaka H, Arakawa H, Yamaguchi T, Shiraishi K, Fukuda S, Matsui K, Takei Y, Nakamura Y.
    Nature; 2000 Mar 02; 404(6773):42-9. PubMed ID: 10716435
    [Abstract] [Full Text] [Related]

  • 19. Structural basis on the dityrosyl-diiron radical cluster and the functional differences of human ribonucleotide reductase small subunits hp53R2 and hRRM2.
    Zhou B, Su L, Yuan YC, Un F, Wang N, Patel M, Xi B, Hu S, Yen Y.
    Mol Cancer Ther; 2010 Jun 02; 9(6):1669-79. PubMed ID: 20484015
    [Abstract] [Full Text] [Related]

  • 20. Upregulation of the p53R2 ribonucleotide reductase subunit by nitric oxide.
    Guittet O, Tebbi A, Cottet MH, Vésin F, Lepoivre M.
    Nitric Oxide; 2008 Sep 02; 19(2):84-94. PubMed ID: 18474260
    [Abstract] [Full Text] [Related]

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