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379 related items for PubMed ID: 12637254

  • 1. Gastritis increases resistance to aspirin-induced mucosal injury via COX-2-mediated lipoxin synthesis.
    Souza MH, de Lima OM, Zamuner SR, Fiorucci S, Wallace JL.
    Am J Physiol Gastrointest Liver Physiol; 2003 Jul; 285(1):G54-61. PubMed ID: 12637254
    [Abstract] [Full Text] [Related]

  • 2. Aspirin, but not NO-releasing aspirin (NCX-4016), interacts with selective COX-2 inhibitors to aggravate gastric damage and inflammation.
    Wallace JL, Zamuner SR, McKnight W, Dicay M, Mencarelli A, del Soldato P, Fiorucci S.
    Am J Physiol Gastrointest Liver Physiol; 2004 Jan; 286(1):G76-81. PubMed ID: 14665439
    [Abstract] [Full Text] [Related]

  • 3. Cyclooxygenase-2-derived lipoxin A4 increases gastric resistance to aspirin-induced damage.
    Fiorucci S, de Lima OM, Mencarelli A, Palazzetti B, Distrutti E, McKnight W, Dicay M, Ma L, Romano M, Morelli A, Wallace JL.
    Gastroenterology; 2002 Nov; 123(5):1598-606. PubMed ID: 12404234
    [Abstract] [Full Text] [Related]

  • 4. Roles of endogenous prostaglandins and cyclooxygenase izoenzymes in mucosal defense of inflamed rat stomach.
    Takeeda M, Hayashi Y, Yamato M, Murakami M, Takeuchi K.
    J Physiol Pharmacol; 2004 Mar; 55(1 Pt 2):193-205. PubMed ID: 15082878
    [Abstract] [Full Text] [Related]

  • 5. Lipoxins in gastric mucosal health and disease.
    Wallace JL, de Lima OM, Fiorucci S.
    Prostaglandins Leukot Essent Fatty Acids; 2005 Mar; 73(3-4):251-5. PubMed ID: 16024242
    [Abstract] [Full Text] [Related]

  • 6. Ulcerogenic influence of selective cyclooxygenase-2 inhibitors in the rat stomach with adjuvant-induced arthritis.
    Kato S, Ogawa Y, Kanatsu K, Okayama M, Watanabe T, Arakawa T, Takeuchi K.
    J Pharmacol Exp Ther; 2002 Nov; 303(2):503-9. PubMed ID: 12388629
    [Abstract] [Full Text] [Related]

  • 7. Rofecoxib produces intestinal but not gastric damage in the presence of a low dose of indomethacin in rats.
    Yokota A, Taniguchi M, Takahira Y, Tanaka A, Takeuchi K.
    J Pharmacol Exp Ther; 2005 Jul; 314(1):302-9. PubMed ID: 15831440
    [Abstract] [Full Text] [Related]

  • 8. Relative contribution of acetylated cyclo-oxygenase (COX)-2 and 5-lipooxygenase (LOX) in regulating gastric mucosal integrity and adaptation to aspirin.
    Fiorucci S, Distrutti E, de Lima OM, Romano M, Mencarelli A, Barbanti M, Palazzini E, Morelli A, Wallace JL.
    FASEB J; 2003 Jun; 17(9):1171-3. PubMed ID: 12709408
    [Abstract] [Full Text] [Related]

  • 9. Cyclooxygenase-2 selective and nitric oxide-releasing nonsteroidal anti-inflammatory drugs and gastric mucosal responses.
    Takeuchi K, Suzuki K, Yamamoto H, Araki H, Mizoguchi H, Ukawa H.
    J Physiol Pharmacol; 1998 Dec; 49(4):501-13. PubMed ID: 10069692
    [Abstract] [Full Text] [Related]

  • 10. Nitric oxide (NO)-releasing naproxen (HCT-3012 [(S)-6-methoxy-alpha-methyl-2-naphthaleneacetic Acid 4-(nitrooxy)butyl ester]) interactions with aspirin in gastric mucosa of arthritic rats reveal a role for aspirin-triggered lipoxin, prostaglandins, and NO in gastric protection.
    Fiorucci S, Di Lorenzo A, Renga B, Farneti S, Morelli A, Cirino G.
    J Pharmacol Exp Ther; 2004 Dec; 311(3):1264-71. PubMed ID: 15297470
    [Abstract] [Full Text] [Related]

  • 11. Physiological mediators in nonsteroidal anti-inflammatory drugs (NSAIDs)-induced impairment of gastric mucosal defense and adaptation. Focus on nitric oxide and lipoxins.
    Brzozowski T, Konturek PC, Pajdo R, Ptak-Belowska A, Kwiecien S, Pawlik M, Drozdowicz D, Sliwowski Z, Brzozowski B, Konturek SJ, Pawlik WW.
    J Physiol Pharmacol; 2008 Aug; 59 Suppl 2():89-102. PubMed ID: 18812631
    [Abstract] [Full Text] [Related]

  • 12. Healing of chronic gastric ulcers in diabetic rats treated with native aspirin, nitric oxide (NO)-derivative of aspirin and cyclooxygenase (COX)-2 inhibitor.
    Brzozowska I, Targosz A, Sliwowski Z, Kwiecien S, Drozdowicz D, Pajdo R, Konturek PC, Brzozowski T, Pawlik M, Konturek SJ, Pawlik WW, Hahn EG.
    J Physiol Pharmacol; 2004 Dec; 55(4):773-90. PubMed ID: 15613743
    [Abstract] [Full Text] [Related]

  • 13. A magic bullet for mucosal protection...and aspirin is the trigger!
    Wallace JL, Fiorucci S.
    Trends Pharmacol Sci; 2003 Jul; 24(7):323-6. PubMed ID: 12871661
    [No Abstract] [Full Text] [Related]

  • 14. Lansoprazole induces mucosal protection through gastrin receptor-dependent up-regulation of cyclooxygenase-2 in rats.
    Tsuji S, Sun WH, Tsujii M, Kawai N, Kimura A, Kakiuchi Y, Yasumaru S, Komori M, Murata H, Sasaki Y, Kawano S, Hori M.
    J Pharmacol Exp Ther; 2002 Dec; 303(3):1301-8. PubMed ID: 12438555
    [Abstract] [Full Text] [Related]

  • 15. Effects of specific inhibition of cyclo-oxygenase-1 and cyclo-oxygenase-2 in the rat stomach with normal mucosa and after acid challenge.
    Gretzer B, Maricic N, Respondek M, Schuligoi R, Peskar BM.
    Br J Pharmacol; 2001 Apr; 132(7):1565-73. PubMed ID: 11264251
    [Abstract] [Full Text] [Related]

  • 16. Anti-inflammatory effect of two isoforms of COX in H. pylori-induced gastritis in mice: possible involvement of PGE2.
    Tanigawa T, Watanabe T, Hamaguchi M, Sasaki E, Tominaga K, Fujiwara Y, Oshitani N, Matsumoto T, Higuchi K, Arakawa T.
    Am J Physiol Gastrointest Liver Physiol; 2004 Jan; 286(1):G148-56. PubMed ID: 12958020
    [Abstract] [Full Text] [Related]

  • 17. Selective cyclo-oxygenase-2 inhibitors and their influence on the protective effect of a mild irritant in the rat stomach.
    Gretzer B, Ehrlich K, Maricic N, Lambrecht N, Respondek M, Peskar BM.
    Br J Pharmacol; 1998 Mar; 123(5):927-35. PubMed ID: 9535022
    [Abstract] [Full Text] [Related]

  • 18. Interaction of a selective cyclooxygenase-2 inhibitor with aspirin and NO-releasing aspirin in the human gastric mucosa.
    Fiorucci S, Santucci L, Wallace JL, Sardina M, Romano M, del Soldato P, Morelli A.
    Proc Natl Acad Sci U S A; 2003 Sep 16; 100(19):10937-41. PubMed ID: 12960371
    [Abstract] [Full Text] [Related]

  • 19. [Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats].
    Shen X.
    Zhonghua Yi Xue Za Zhi; 2001 Nov 25; 81(22):1380-3. PubMed ID: 11930633
    [Abstract] [Full Text] [Related]

  • 20. Gastrin enhances gastric mucosal integrity through cyclooxygenase-2 upregulation in rats.
    Komori M, Tsuji S, Sun WH, Tsujii M, Kawai N, Yasumaru M, Kakiuchi Y, Kimura A, Sasaki Y, Higashiyama S, Kawano S, Hori M.
    Am J Physiol Gastrointest Liver Physiol; 2002 Dec 25; 283(6):G1368-78. PubMed ID: 12388195
    [Abstract] [Full Text] [Related]

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