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223 related items for PubMed ID: 12637498

  • 1. The role of the Ah receptor and p38 in benzo[a]pyrene-7,8-dihydrodiol and benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced apoptosis.
    Chen S, Nguyen N, Tamura K, Karin M, Tukey RH.
    J Biol Chem; 2003 May 23; 278(21):19526-33. PubMed ID: 12637498
    [Abstract] [Full Text] [Related]

  • 2. Apoptosis in Daudi human B cells in response to benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol.
    Salas VM, Burchiel SW.
    Toxicol Appl Pharmacol; 1998 Aug 23; 151(2):367-76. PubMed ID: 9707513
    [Abstract] [Full Text] [Related]

  • 3. Role of cell signaling in B[a]P-induced apoptosis: characterization of unspecific effects of cell signaling inhibitors and apoptotic effects of B[a]P metabolites.
    Solhaug A, Øvrebø S, Mollerup S, Låg M, Schwarze PE, Nesnow S, Holme JA.
    Chem Biol Interact; 2005 Jan 15; 151(2):101-19. PubMed ID: 15698582
    [Abstract] [Full Text] [Related]

  • 4. Differential mutagenicity and cytotoxicity of (+/-)-benzo[a]pyrene-trans-7,8-dihydrodiol and (+/-)-anti-benzo[a]pyrene-trans-7,8-dihydrodiol-9,10-epoxide in genetically engineered human fibroblasts.
    Quan T, Reiners JJ, Culp SJ, Richter P, States JC.
    Mol Carcinog; 1995 Feb 15; 12(2):91-102. PubMed ID: 7662121
    [Abstract] [Full Text] [Related]

  • 5. Role and interaction of p53, BAX and the stress-activated protein kinases p38 and JNK in benzo(a)pyrene-diolepoxide induced apoptosis in human colon carcinoma cells.
    Donauer J, Schreck I, Liebel U, Weiss C.
    Arch Toxicol; 2012 Feb 15; 86(2):329-37. PubMed ID: 21983885
    [Abstract] [Full Text] [Related]

  • 6. Benzo[a]pyrene-7,8-diol-9,10-epoxide causes caspase-mediated apoptosis in H460 human lung cancer cell line.
    Xiao H, Rawal M, Hahm ER, Singh SV.
    Cell Cycle; 2007 Nov 15; 6(22):2826-34. PubMed ID: 17986867
    [Abstract] [Full Text] [Related]

  • 7. The nucleotide excision repair protein XPC is essential for bulky DNA adducts to promote interleukin-6 expression via the activation of p38-SAPK.
    Schreck I, Grico N, Hansjosten I, Marquardt C, Bormann S, Seidel A, Kvietkova DL, Pieniazek D, Segerbäck D, Diabaté S, van der Horst GT, Oesch-Bartlomowicz B, Oesch F, Weiss C.
    Oncogene; 2016 Feb 18; 35(7):908-18. PubMed ID: 25982271
    [Abstract] [Full Text] [Related]

  • 8. ERK kinase inhibition stabilizes the aryl hydrocarbon receptor: implications for transcriptional activation and protein degradation.
    Chen S, Operaña T, Bonzo J, Nguyen N, Tukey RH.
    J Biol Chem; 2005 Feb 11; 280(6):4350-9. PubMed ID: 15572374
    [Abstract] [Full Text] [Related]

  • 9. Polycyclic aromatic hydrocarbons induce both apoptotic and anti-apoptotic signals in Hepa1c1c7 cells.
    Solhaug A, Refsnes M, Låg M, Schwarze PE, Husøy T, Holme JA.
    Carcinogenesis; 2004 May 11; 25(5):809-19. PubMed ID: 14729587
    [Abstract] [Full Text] [Related]

  • 10. Curcumin activates the aryl hydrocarbon receptor yet significantly inhibits (-)-benzo(a)pyrene-7R-trans-7,8-dihydrodiol bioactivation in oral squamous cell carcinoma cells and oral mucosa.
    Rinaldi AL, Morse MA, Fields HW, Rothas DA, Pei P, Rodrigo KA, Renner RJ, Mallery SR.
    Cancer Res; 2002 Oct 01; 62(19):5451-6. PubMed ID: 12359752
    [Abstract] [Full Text] [Related]

  • 11. Expression of human glutathione S-transferase P1 confers resistance to benzo[a]pyrene or benzo[a]pyrene-7,8-dihydrodiol mutagenesis, macromolecular alkylation and formation of stable N2-Gua-BPDE adducts in stably transfected V79MZ cells co-expressing hCYP1A1.
    Kushman ME, Kabler SL, Fleming MH, Ravoori S, Gupta RC, Doehmer J, Morrow CS, Townsend AJ.
    Carcinogenesis; 2007 Jan 01; 28(1):207-14. PubMed ID: 16885195
    [Abstract] [Full Text] [Related]

  • 12. Factors influencing elevation of intracellular Ca2+ in the MCF-10A human mammary epithelial cell line by carcinogenic polycyclic aromatic hydrocarbons.
    Tannheimer SL, Lauer FT, Lane J, Burchiel SW.
    Mol Carcinog; 1999 May 01; 25(1):48-54. PubMed ID: 10331744
    [Abstract] [Full Text] [Related]

  • 13. Inhibitory effects of chrysoeriol on DNA adduct formation with benzo[a]pyrene in MCF-7 breast cancer cells.
    Takemura H, Nagayoshi H, Matsuda T, Sakakibara H, Morita M, Matsui A, Ohura T, Shimoi K.
    Toxicology; 2010 May 01; 274(1-3):42-8. PubMed ID: 20553787
    [Abstract] [Full Text] [Related]

  • 14. DNA polymerase kappa is specifically required for recovery from the benzo[a]pyrene-dihydrodiol epoxide (BPDE)-induced S-phase checkpoint.
    Bi X, Slater DM, Ohmori H, Vaziri C.
    J Biol Chem; 2005 Jun 10; 280(23):22343-55. PubMed ID: 15817457
    [Abstract] [Full Text] [Related]

  • 15. Metabolic activation of benzo[a]pyrene-7,8-dihydrodiol and benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide to protein-binding products and the inhibitory effect of glutathione and cysteine.
    Jernström B, Dock L, Martinez M.
    Carcinogenesis; 1984 Feb 10; 5(2):199-204. PubMed ID: 6421502
    [Abstract] [Full Text] [Related]

  • 16. Benzo[a]pyrene induces apoptosis in RL95-2 human endometrial cancer cells by cytochrome P450 1A1 activation.
    Kim JY, Chung JY, Park JE, Lee SG, Kim YJ, Cha MS, Han MS, Lee HJ, Yoo YH, Kim JM.
    Endocrinology; 2007 Oct 10; 148(10):5112-22. PubMed ID: 17640999
    [Abstract] [Full Text] [Related]

  • 17. Attenuation of BPDE-induced p53 accumulation by TPA is associated with a decrease in stability and phosphorylation of p53 and downregulation of NFkappaB activation: role of p38 MAP kinase.
    Mukherjee JJ, Sikka HC.
    Carcinogenesis; 2006 Mar 10; 27(3):631-8. PubMed ID: 16244358
    [Abstract] [Full Text] [Related]

  • 18. Abundance of aryl hydrocarbon receptor potentiates benzo[a]pyrene-induced apoptosis in Hepa1c1c7 cells via CYP1A1 activation.
    Chung JY, Kim JY, Kim WR, Lee SG, Kim YJ, Park JE, Hong YP, Chun YJ, Park YC, Oh S, Yoo KS, Yoo YH, Kim JM.
    Toxicology; 2007 Jun 03; 235(1-2):62-72. PubMed ID: 17433523
    [Abstract] [Full Text] [Related]

  • 19. Activation of the aromatic hydrocarbon receptor pathway is not sufficient for transcriptional repression of BRCA-1: requirements for metabolism of benzo[a]pyrene to 7r,8t-dihydroxy-9t,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.
    Jeffy BD, Chirnomas RB, Chen EJ, Gudas JM, Romagnolo DF.
    Cancer Res; 2002 Jan 01; 62(1):113-21. PubMed ID: 11782367
    [Abstract] [Full Text] [Related]

  • 20. DNA synthesis inhibition in response to benzo[a]pyrene dihydrodiol epoxide is associated with attenuation of p(34)cdc2: Role of p53.
    Mukherjee JJ, Kumar S.
    Mutat Res; 2013 Jul 04; 755(1):61-7. PubMed ID: 23692869
    [Abstract] [Full Text] [Related]

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