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203 related items for PubMed ID: 12641442

  • 1. Reactive oxygen species are involved in arsenic trioxide inhibition of pyruvate dehydrogenase activity.
    Samikkannu T, Chen CH, Yih LH, Wang AS, Lin SY, Chen TC, Jan KY.
    Chem Res Toxicol; 2003 Mar; 16(3):409-14. PubMed ID: 12641442
    [Abstract] [Full Text] [Related]

  • 2. Reactive oxygen species-mediated inactivation of pyruvate dehydrogenase.
    Tabatabaie T, Potts JD, Floyd RA.
    Arch Biochem Biophys; 1996 Dec 15; 336(2):290-6. PubMed ID: 8954577
    [Abstract] [Full Text] [Related]

  • 3. Pharmacologic inhibitors of extracellular signal-regulated kinase (ERKs) and c-Jun NH(2)-terminal kinase (JNK) decrease glutathione content and sensitize human promonocytic leukemia cells to arsenic trioxide-induced apoptosis.
    Ramos AM, Fernandez C, Amrán D, Esteban D, de Blas E, Palacios MA, Aller P.
    J Cell Physiol; 2006 Dec 15; 209(3):1006-15. PubMed ID: 16972261
    [Abstract] [Full Text] [Related]

  • 4. TNF-alpha/cycloheximide-induced apoptosis in intestinal epithelial cells requires Rac1-regulated reactive oxygen species.
    Jin S, Ray RM, Johnson LR.
    Am J Physiol Gastrointest Liver Physiol; 2008 Apr 15; 294(4):G928-37. PubMed ID: 18218673
    [Abstract] [Full Text] [Related]

  • 5. Copper chelation by D-penicillamine generates reactive oxygen species that are cytotoxic to human leukemia and breast cancer cells.
    Gupte A, Mumper RJ.
    Free Radic Biol Med; 2007 Nov 01; 43(9):1271-8. PubMed ID: 17893040
    [Abstract] [Full Text] [Related]

  • 6. Modulation of arsenic trioxide-induced apoptosis by genistein and functionally related agents in U937 human leukaemia cells. Regulation by ROS and mitogen-activated protein kinases.
    Sánchez Y, Calle C, de Blas E, Aller P.
    Chem Biol Interact; 2009 Nov 10; 182(1):37-44. PubMed ID: 19720055
    [Abstract] [Full Text] [Related]

  • 7. Effects of 1, 6-Bis[4-(4-amino-3-hydroxyphenoxy)phenyl]diamantane (DPD), a reactive oxygen species and apoptosis inducing agent, on human leukemia cells in vitro and in vivo.
    Chang YF, Chi CW, Chern YT, Wang JJ.
    Toxicol Appl Pharmacol; 2005 Jan 01; 202(1):1-12. PubMed ID: 15589971
    [Abstract] [Full Text] [Related]

  • 8. Methylated metabolites of arsenic trioxide are more potent than arsenic trioxide as apoptotic but not differentiation inducers in leukemia and lymphoma cells.
    Chen GQ, Zhou L, Styblo M, Walton F, Jing Y, Weinberg R, Chen Z, Waxman S.
    Cancer Res; 2003 Apr 15; 63(8):1853-9. PubMed ID: 12702573
    [Abstract] [Full Text] [Related]

  • 9. Reperfusion-induced translocation of deltaPKC to cardiac mitochondria prevents pyruvate dehydrogenase reactivation.
    Churchill EN, Murriel CL, Chen CH, Mochly-Rosen D, Szweda LI.
    Circ Res; 2005 Jul 08; 97(1):78-85. PubMed ID: 15961716
    [Abstract] [Full Text] [Related]

  • 10. Intracellular GSH level is a factor in As4.1 juxtaglomerular cell death by arsenic trioxide.
    Han YH, Kim SZ, Kim SH, Park WH.
    J Cell Biochem; 2008 Jun 01; 104(3):995-1009. PubMed ID: 18247324
    [Abstract] [Full Text] [Related]

  • 11. Dynamic effects of autophagy on arsenic trioxide-induced death of human leukemia cell line HL60 cells.
    Yang YP, Liang ZQ, Gao B, Jia YL, Qin ZH.
    Acta Pharmacol Sin; 2008 Jan 01; 29(1):123-34. PubMed ID: 18158874
    [Abstract] [Full Text] [Related]

  • 12. JWA is required for arsenic trioxide induced apoptosis in HeLa and MCF-7 cells via reactive oxygen species and mitochondria linked signal pathway.
    Zhou J, Ye J, Zhao X, Li A, Zhou J.
    Toxicol Appl Pharmacol; 2008 Jul 01; 230(1):33-40. PubMed ID: 18387645
    [Abstract] [Full Text] [Related]

  • 13. Apoptosis in arsenic trioxide-treated Calu-6 lung cells is correlated with the depletion of GSH levels rather than the changes of ROS levels.
    Han YH, Kim SH, Kim SZ, Park WH.
    J Cell Biochem; 2008 Jun 01; 104(3):862-78. PubMed ID: 18393359
    [Abstract] [Full Text] [Related]

  • 14. NADPH oxidase-derived reactive oxygen species are responsible for the high susceptibility to arsenic cytotoxicity in acute promyelocytic leukemia cells.
    Wang J, Li L, Cang H, Shi G, Yi J.
    Leuk Res; 2008 Mar 01; 32(3):429-36. PubMed ID: 17804067
    [Abstract] [Full Text] [Related]

  • 15. Role of Fenton chemistry in thiol-induced toxicity and apoptosis.
    Held KD, Sylvester FC, Hopcia KL, Biaglow JE.
    Radiat Res; 1996 May 01; 145(5):542-53. PubMed ID: 8619019
    [Abstract] [Full Text] [Related]

  • 16. Antitumor activity of arsenic trioxide on retinoblastoma: cell differentiation and apoptosis depending on arsenic trioxide concentration.
    Kim JH, Kim JH, Yu YS, Kim DH, Kim CJ, Kim KW.
    Invest Ophthalmol Vis Sci; 2009 Apr 01; 50(4):1819-23. PubMed ID: 19060284
    [Abstract] [Full Text] [Related]

  • 17. Mechanisms of H2O2-induced oxidative stress in endothelial cells.
    Coyle CH, Martinez LJ, Coleman MC, Spitz DR, Weintraub NL, Kader KN.
    Free Radic Biol Med; 2006 Jun 15; 40(12):2206-13. PubMed ID: 16785034
    [Abstract] [Full Text] [Related]

  • 18. Dithiol compounds at low concentrations increase arsenite toxicity.
    Jan KY, Wang TC, Ramanathan B, Gurr JR.
    Toxicol Sci; 2006 Apr 15; 90(2):432-9. PubMed ID: 16421177
    [Abstract] [Full Text] [Related]

  • 19. Dithiothreitol abrogates the effect of arsenic trioxide on normal rat liver mitochondria and human hepatocellular carcinoma cells.
    Paul MK, Kumar R, Mukhopadhyay AK.
    Toxicol Appl Pharmacol; 2008 Jan 15; 226(2):140-52. PubMed ID: 18022205
    [Abstract] [Full Text] [Related]

  • 20. Effects of co-administration of dietary sodium arsenite and an NADPH oxidase inhibitor on the rat bladder epithelium.
    Suzuki S, Arnold LL, Pennington KL, Kakiuchi-Kiyota S, Cohen SM.
    Toxicology; 2009 Jun 30; 261(1-2):41-6. PubMed ID: 19397947
    [Abstract] [Full Text] [Related]


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