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177 related items for PubMed ID: 12644019

  • 1. Cycling B-CLL cells are highly susceptible to inhibition of the proteasome: involvement of p27, early D-type cyclins, Bax, and caspase-dependent and -independent pathways.
    Bogner C, Schneller F, Hipp S, Ringshausen I, Peschel C, Decker T.
    Exp Hematol; 2003 Mar; 31(3):218-25. PubMed ID: 12644019
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of proteasome function induced apoptosis in gastric cancer.
    Fan XM, Wong BC, Wang WP, Zhou XM, Cho CH, Yuen ST, Leung SY, Lin MC, Kung HF, Lam SK.
    Int J Cancer; 2001 Aug 15; 93(4):481-8. PubMed ID: 11477551
    [Abstract] [Full Text] [Related]

  • 3. p27Kip1 accumulation by inhibition of proteasome function induces apoptosis in oral squamous cell carcinoma cells.
    Kudo Y, Takata T, Ogawa I, Kaneda T, Sato S, Takekoshi T, Zhao M, Miyauchi M, Nikai H.
    Clin Cancer Res; 2000 Mar 15; 6(3):916-23. PubMed ID: 10741716
    [Abstract] [Full Text] [Related]

  • 4. Role of proteasomes in T cell activation and proliferation.
    Wang X, Luo H, Chen H, Duguid W, Wu J.
    J Immunol; 1998 Jan 15; 160(2):788-801. PubMed ID: 9551914
    [Abstract] [Full Text] [Related]

  • 5. Proteasome inhibitor-induced apoptosis of B-chronic lymphocytic leukaemia cells involves cytochrome c release and caspase activation, accompanied by formation of an approximately 700 kDa Apaf-1 containing apoptosome complex.
    Almond JB, Snowden RT, Hunter A, Dinsdale D, Cain K, Cohen GM.
    Leukemia; 2001 Sep 15; 15(9):1388-97. PubMed ID: 11516099
    [Abstract] [Full Text] [Related]

  • 6. Proteasome inhibitors induce mitochondria-independent apoptosis in human glioma cells.
    Kitagawa H, Tani E, Ikemoto H, Ozaki I, Nakano A, Omura S.
    FEBS Lett; 1999 Jan 25; 443(2):181-6. PubMed ID: 9989601
    [Abstract] [Full Text] [Related]

  • 7. Proteasome inhibitors induced caspase-dependent apoptosis and accumulation of p21WAF1/Cip1 in human immature leukemic cells.
    Naujokat C, Sezer O, Zinke H, Leclere A, Hauptmann S, Possinger K.
    Eur J Haematol; 2000 Oct 25; 65(4):221-36. PubMed ID: 11073163
    [Abstract] [Full Text] [Related]

  • 8. Cell cycle progression of chronic lymphocytic leukemia cells is controlled by cyclin D2, cyclin D3, cyclin-dependent kinase (cdk) 4 and the cdk inhibitor p27.
    Decker T, Schneller F, Hipp S, Miething C, Jahn T, Duyster J, Peschel C.
    Leukemia; 2002 Mar 25; 16(3):327-34. PubMed ID: 11896535
    [Abstract] [Full Text] [Related]

  • 9. Fludarabine-induced apoptosis of B chronic lymphocytic leukemia cells includes early cleavage of p27kip1 by caspases.
    Sanhes L, Tang R, Delmer A, DeCaprio JA, Ajchenbaum-Cymbalista F.
    Leukemia; 2003 Jun 25; 17(6):1104-11. PubMed ID: 12764376
    [Abstract] [Full Text] [Related]

  • 10. Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells.
    Xiao D, Johnson CS, Trump DL, Singh SV.
    Mol Cancer Ther; 2004 May 25; 3(5):567-75. PubMed ID: 15141014
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of ubiquitin-proteasome pathway activates a caspase-3-like protease and induces Bcl-2 cleavage in human M-07e leukaemic cells.
    Zhang XM, Lin H, Chen C, Chen BD.
    Biochem J; 1999 May 15; 340 ( Pt 1)(Pt 1):127-33. PubMed ID: 10229667
    [Abstract] [Full Text] [Related]

  • 12. Proteasome inhibitor-induced apoptosis of glioma cells involves the processing of multiple caspases and cytochrome c release.
    Wagenknecht B, Hermisson M, Groscurth P, Liston P, Krammer PH, Weller M.
    J Neurochem; 2000 Dec 15; 75(6):2288-97. PubMed ID: 11080180
    [Abstract] [Full Text] [Related]

  • 13. Induction of G1 arrest and apoptosis in human jurkat T cells by pentagalloylglucose through inhibiting proteasome activity and elevating p27Kip1, p21Cip1/WAF1, and Bax proteins.
    Chen WJ, Lin JK.
    J Biol Chem; 2004 Apr 02; 279(14):13496-505. PubMed ID: 14726525
    [Abstract] [Full Text] [Related]

  • 14. Cyclin-dependent kinase activity is required for apoptotic death but not inclusion formation in cortical neurons after proteasomal inhibition.
    Rideout HJ, Wang Q, Park DS, Stefanis L.
    J Neurosci; 2003 Feb 15; 23(4):1237-45. PubMed ID: 12598612
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  • 19. Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts.
    An B, Goldfarb RH, Siman R, Dou QP.
    Cell Death Differ; 1998 Dec 15; 5(12):1062-75. PubMed ID: 9894613
    [Abstract] [Full Text] [Related]

  • 20. Rapamycin-induced G1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivin.
    Decker T, Hipp S, Ringshausen I, Bogner C, Oelsner M, Schneller F, Peschel C.
    Blood; 2003 Jan 01; 101(1):278-85. PubMed ID: 12393642
    [Abstract] [Full Text] [Related]

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