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661 related items for PubMed ID: 12645577

  • 1. c-Src-dependent tyrosine phosphorylation of IKKbeta is involved in tumor necrosis factor-alpha-induced intercellular adhesion molecule-1 expression.
    Huang WC, Chen JJ, Chen CC.
    J Biol Chem; 2003 Mar 14; 278(11):9944-52. PubMed ID: 12645577
    [Abstract] [Full Text] [Related]

  • 2.
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  • 3. Interferon-gamma-induced epithelial ICAM-1 expression and monocyte adhesion. Involvement of protein kinase C-dependent c-Src tyrosine kinase activation pathway.
    Chang YJ, Holtzman MJ, Chen CC.
    J Biol Chem; 2002 Mar 01; 277(9):7118-26. PubMed ID: 11751911
    [Abstract] [Full Text] [Related]

  • 4. Tumor necrosis factor alpha-induced activation of downstream NF-kappaB site of the promoter mediates epithelial ICAM-1 expression and monocyte adhesion. Involvement of PKCalpha, tyrosine kinase, and IKK2, but not MAPKs, pathway.
    Chen C, Chou C, Sun Y, Huang W.
    Cell Signal; 2001 Aug 01; 13(8):543-53. PubMed ID: 11483407
    [Abstract] [Full Text] [Related]

  • 5. TNF-alpha-induced cyclooxygenase-2 expression in human lung epithelial cells: involvement of the phospholipase C-gamma 2, protein kinase C-alpha, tyrosine kinase, NF-kappa B-inducing kinase, and I-kappa B kinase 1/2 pathway.
    Chen CC, Sun YT, Chen JJ, Chiu KT.
    J Immunol; 2000 Sep 01; 165(5):2719-28. PubMed ID: 10946303
    [Abstract] [Full Text] [Related]

  • 6. Protein kinase calpha but not p44/42 mitogen-activated protein kinase, p38, or c-Jun NH(2)-terminal kinase is required for intercellular adhesion molecule-1 expression mediated by interleukin-1beta: involvement of sequential activation of tyrosine kinase, nuclear factor-kappaB-inducing kinase, and IkappaB kinase 2.
    Chen CC, Chen JJ, Chou CY.
    Mol Pharmacol; 2000 Dec 01; 58(6):1479-89. PubMed ID: 11093788
    [Abstract] [Full Text] [Related]

  • 7. Differential role of Janus family kinases (JAKs) in interferon-gamma-induced lung epithelial ICAM-1 expression: involving protein interactions between JAKs, phospholipase Cgamma, c-Src, and STAT1.
    Chang YJ, Holtzman MJ, Chen CC.
    Mol Pharmacol; 2004 Mar 01; 65(3):589-98. PubMed ID: 14978237
    [Abstract] [Full Text] [Related]

  • 8. Protein kinase C-zeta mediates TNF-alpha-induced ICAM-1 gene transcription in endothelial cells.
    Rahman A, Anwar KN, Malik AB.
    Am J Physiol Cell Physiol; 2000 Oct 01; 279(4):C906-14. PubMed ID: 11003570
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of ICAM-1 gene expression, monocyte adhesion and cancer cell invasion by targeting IKK complex: molecular and functional study of novel alpha-methylene-gamma-butyrolactone derivatives.
    Huang WC, Chan ST, Yang TL, Tzeng CC, Chen CC.
    Carcinogenesis; 2004 Oct 01; 25(10):1925-34. PubMed ID: 15217903
    [Abstract] [Full Text] [Related]

  • 10. Protein kinase C-alpha is an upstream activator of the IkappaB kinase complex in the TPA signal transduction pathway to NF-kappaB in U2OS cells.
    Vertegaal AC, Kuiperij HB, Yamaoka S, Courtois G, van der Eb AJ, Zantema A.
    Cell Signal; 2000 Dec 01; 12(11-12):759-68. PubMed ID: 11152962
    [Abstract] [Full Text] [Related]

  • 11. Tyrosine kinase p56lck regulates cell motility and nuclear factor kappaB-mediated secretion of urokinase type plasminogen activator through tyrosine phosphorylation of IkappaBalpha following hypoxia/reoxygenation.
    Mahabeleshwar GH, Kundu GC.
    J Biol Chem; 2003 Dec 26; 278(52):52598-612. PubMed ID: 14534291
    [Abstract] [Full Text] [Related]

  • 12. Basic fibroblast growth factor stimulates fibronectin expression through phospholipase C gamma, protein kinase C alpha, c-Src, NF-kappaB, and p300 pathway in osteoblasts.
    Tang CH, Yang RS, Chen YF, Fu WM.
    J Cell Physiol; 2007 Apr 26; 211(1):45-55. PubMed ID: 17252537
    [Abstract] [Full Text] [Related]

  • 13. Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway.
    Sakurai H, Suzuki S, Kawasaki N, Nakano H, Okazaki T, Chino A, Doi T, Saiki I.
    J Biol Chem; 2003 Sep 19; 278(38):36916-23. PubMed ID: 12842894
    [Abstract] [Full Text] [Related]

  • 14. Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis.
    Takada Y, Singh S, Aggarwal BB.
    J Biol Chem; 2004 Apr 09; 279(15):15096-104. PubMed ID: 14711835
    [Abstract] [Full Text] [Related]

  • 15. Roles for homotypic interactions and transautophosphorylation in IkappaB kinase beta IKKbeta) activation [corrected].
    Tang ED, Inohara N, Wang CY, Nuñez G, Guan KL.
    J Biol Chem; 2003 Oct 03; 278(40):38566-70. PubMed ID: 12890679
    [Abstract] [Full Text] [Related]

  • 16. Conjugated polyhydroxybenzene derivatives block tumor necrosis factor-alpha-mediated nuclear factor-kappaB activation and cyclooxygenase-2 gene transcription by targeting IkappaB kinase activity.
    Chen CC, Chiu KT, Chan ST, Chern JW.
    Mol Pharmacol; 2001 Dec 03; 60(6):1439-48. PubMed ID: 11723253
    [Abstract] [Full Text] [Related]

  • 17. Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription.
    Buss H, Dörrie A, Schmitz ML, Hoffmann E, Resch K, Kracht M.
    J Biol Chem; 2004 Dec 31; 279(53):55633-43. PubMed ID: 15489227
    [Abstract] [Full Text] [Related]

  • 18. Oxidized phospholipids increase interleukin 8 (IL-8) synthesis by activation of the c-src/signal transducers and activators of transcription (STAT)3 pathway.
    Yeh M, Gharavi NM, Choi J, Hsieh X, Reed E, Mouillesseaux KP, Cole AL, Reddy ST, Berliner JA.
    J Biol Chem; 2004 Jul 16; 279(29):30175-81. PubMed ID: 15143062
    [Abstract] [Full Text] [Related]

  • 19. Lipopolysaccharide induces ICAM-1 expression via a c-Src/NADPH oxidase/ROS-dependent NF-κB pathway in human pulmonary alveolar epithelial cells.
    Cho RL, Yang CC, Lee IT, Lin CC, Chi PL, Hsiao LD, Yang CM.
    Am J Physiol Lung Cell Mol Physiol; 2016 Apr 01; 310(7):L639-57. PubMed ID: 26747779
    [Abstract] [Full Text] [Related]

  • 20. Signal transduction mechanisms involved in S100A4-induced activation of the transcription factor NF-kappaB.
    Grotterød I, Maelandsmo GM, Boye K.
    BMC Cancer; 2010 May 28; 10():241. PubMed ID: 20507646
    [Abstract] [Full Text] [Related]

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