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Journal Abstract Search

124 related items for PubMed ID: 12645994

  • 1. Population analysis of the pharmacokinetics and pharmacodynamics of RWJ-270201 (BCX-1812) in treating experimental influenza A and B virus in healthy volunteers.
    Iyer GR, Liao S, Massarella J.
    AAPS PharmSci; 2002; 4(4):E22. PubMed ID: 12645994
    [Abstract] [Full Text] [Related]

  • 2. Cyclopentane neuraminidase inhibitors with potent in vitro anti-influenza virus activities.
    Smee DF, Huffman JH, Morrison AC, Barnard DL, Sidwell RW.
    Antimicrob Agents Chemother; 2001 Mar; 45(3):743-8. PubMed ID: 11181354
    [Abstract] [Full Text] [Related]

  • 3. In vivo influenza virus-inhibitory effects of the cyclopentane neuraminidase inhibitor RJW-270201.
    Sidwell RW, Smee DF, Huffman JH, Barnard DL, Bailey KW, Morrey JD, Babu YS.
    Antimicrob Agents Chemother; 2001 Mar; 45(3):749-57. PubMed ID: 11181355
    [Abstract] [Full Text] [Related]

  • 4. RWJ-270201 (BCX-1812): a novel neuraminidase inhibitor for influenza.
    Young D, Fowler C, Bush K.
    Philos Trans R Soc Lond B Biol Sci; 2001 Dec 29; 356(1416):1905-13. PubMed ID: 11779391
    [Abstract] [Full Text] [Related]

  • 5. Comparison of the anti-influenza virus activity of RWJ-270201 with those of oseltamivir and zanamivir.
    Bantia S, Parker CD, Ananth SL, Horn LL, Andries K, Chand P, Kotian PL, Dehghani A, El-Kattan Y, Lin T, Hutchison TL, Montgomery JA, Kellog DL, Babu YS.
    Antimicrob Agents Chemother; 2001 Apr 29; 45(4):1162-7. PubMed ID: 11257030
    [Abstract] [Full Text] [Related]

  • 6. Influenza viral load and peramivir kinetics after single administration and proposal of regimens for peramivir administration against resistant variants.
    Sato M, Ito M, Suzuki S, Sakuma H, Takeyama A, Oda S, Watanabe M, Hashimoto K, Miyazaki K, Kawasaki Y, Hosoya M.
    Antimicrob Agents Chemother; 2015 Mar 29; 59(3):1643-9. PubMed ID: 25547357
    [Abstract] [Full Text] [Related]

  • 7. Peramivir (BCX-1812, RWJ-270201): potential new therapy for influenza.
    Sidwell RW, Smee DF.
    Expert Opin Investig Drugs; 2002 Jun 29; 11(6):859-69. PubMed ID: 12036429
    [Abstract] [Full Text] [Related]

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  • 11. Efficacy and tolerability of the oral neuraminidase inhibitor peramivir in experimental human influenza: randomized, controlled trials for prophylaxis and treatment.
    Barroso L, Treanor J, Gubareva L, Hayden FG.
    Antivir Ther; 2005 Jun 29; 10(8):901-10. PubMed ID: 16430195
    [Abstract] [Full Text] [Related]

  • 12. Influence of virus strain, challenge dose, and time of therapy initiation on the in vivo influenza inhibitory effects of RWJ-270201.
    Sidwell RW, Smee DF, Huffman JH, Barnard DL, Morrey JD, Bailey KW, Feng WC, Babu YS, Bush K.
    Antiviral Res; 2001 Sep 29; 51(3):179-87. PubMed ID: 11448729
    [Abstract] [Full Text] [Related]

  • 13. BCX-1812 (RWJ-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design.
    Babu YS, Chand P, Bantia S, Kotian P, Dehghani A, El-Kattan Y, Lin TH, Hutchison TL, Elliott AJ, Parker CD, Ananth SL, Horn LL, Laver GW, Montgomery JA.
    J Med Chem; 2000 Sep 21; 43(19):3482-6. PubMed ID: 11000002
    [No Abstract] [Full Text] [Related]

  • 14. Pharmacokinetics and safety of intravenous peramivir, neuraminidase inhibitor of influenza virus, in healthy Japanese subjects.
    Saisho Y, Ishibashi T, Fukuyama H, Fukase H, Shimada J.
    Antivir Ther; 2017 Sep 21; 22(4):313-323. PubMed ID: 27805571
    [Abstract] [Full Text] [Related]

  • 15. Primary immune system effects of the orally administered cyclopentane neuraminidase inhibitor RWJ-270201 in influenza virus-infected mice.
    Sidwell RW, Smee DF, Bailey KW, Burger RA.
    Int Immunopharmacol; 2001 Jun 21; 1(6):1211-8. PubMed ID: 11407315
    [Abstract] [Full Text] [Related]

  • 16. Pharmacodynamic evaluation of RWJ-270201, a novel neuraminidase inhibitor, in a lethal murine model of influenza predicts efficacy for once-daily dosing.
    Drusano GL, Preston SL, Smee D, Bush K, Bailey K, Sidwell RW.
    Antimicrob Agents Chemother; 2001 Jul 21; 45(7):2115-8. PubMed ID: 11408232
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of influenza virus infections in immunosuppressed mice with orally administered peramivir (BCX-1812).
    Sidwell RW, Bailey KW, Morrey JD, Wong MH, Baldwin TJ, Smee DF.
    Antiviral Res; 2003 Sep 21; 60(1):17-25. PubMed ID: 14516917
    [Abstract] [Full Text] [Related]

  • 18. Pharmacokinetic and pharmacodynamic properties of multiple oral doses of sitagliptin, a dipeptidyl peptidase-IV inhibitor: a double-blind, randomized, placebo-controlled study in healthy male volunteers.
    Bergman AJ, Stevens C, Zhou Y, Yi B, Laethem M, De Smet M, Snyder K, Hilliard D, Tanaka W, Zeng W, Tanen M, Wang AQ, Chen L, Winchell G, Davies MJ, Ramael S, Wagner JA, Herman GA.
    Clin Ther; 2006 Jan 21; 28(1):55-72. PubMed ID: 16490580
    [Abstract] [Full Text] [Related]

  • 19. Combination treatment of influenza A virus infections in cell culture and in mice with the cyclopentane neuraminidase inhibitor RWJ-270201 and ribavirin.
    Smee DF, Bailey KW, Morrison AC, Sidwell RW.
    Chemotherapy; 2002 May 21; 48(2):88-93. PubMed ID: 12011541
    [Abstract] [Full Text] [Related]

  • 20. [Peramivir. A new and potent neuraminidase inhibitor for the treatment of influenza].
    Reina J.
    Rev Esp Quimioter; 2006 Dec 21; 19(4):317-22. PubMed ID: 17235399
    [No Abstract] [Full Text] [Related]

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