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767 related items for PubMed ID: 12646661

  • 1. IL-12 deficiency in MRL-Fas(lpr) mice delays nephritis and intrarenal IFN-gamma expression, and diminishes systemic pathology.
    Kikawada E, Lenda DM, Kelley VR.
    J Immunol; 2003 Apr 01; 170(7):3915-25. PubMed ID: 12646661
    [Abstract] [Full Text] [Related]

  • 2. Negative role of colony-stimulating factor-1 in macrophage, T cell, and B cell mediated autoimmune disease in MRL-Fas(lpr) mice.
    Lenda DM, Stanley ER, Kelley VR.
    J Immunol; 2004 Oct 01; 173(7):4744-54. PubMed ID: 15383612
    [Abstract] [Full Text] [Related]

  • 3. IFN-gamma receptor signaling is essential for the initiation, acceleration, and destruction of autoimmune kidney disease in MRL-Fas(lpr) mice.
    Schwarting A, Wada T, Kinoshita K, Tesch G, Kelley VR.
    J Immunol; 1998 Jul 01; 161(1):494-503. PubMed ID: 9647261
    [Abstract] [Full Text] [Related]

  • 4. IL-12 drives IFN-gamma-dependent autoimmune kidney disease in MRL-Fas(lpr) mice.
    Schwarting A, Tesch G, Kinoshita K, Maron R, Weiner HL, Kelley VR.
    J Immunol; 1999 Dec 15; 163(12):6884-91. PubMed ID: 10586090
    [Abstract] [Full Text] [Related]

  • 5. IFN-gamma limits macrophage expansion in MRL-Fas(lpr) autoimmune interstitial nephritis: a negative regulatory pathway.
    Schwarting A, Moore K, Wada T, Tesch G, Yoon HJ, Kelley VR.
    J Immunol; 1998 Apr 15; 160(8):4074-81. PubMed ID: 9558118
    [Abstract] [Full Text] [Related]

  • 6. Interleukin 6 (IL-6) deficiency delays lupus nephritis in MRL-Faslpr mice: the IL-6 pathway as a new therapeutic target in treatment of autoimmune kidney disease in systemic lupus erythematosus.
    Cash H, Relle M, Menke J, Brochhausen C, Jones SA, Topley N, Galle PR, Schwarting A.
    J Rheumatol; 2010 Jan 15; 37(1):60-70. PubMed ID: 19955044
    [Abstract] [Full Text] [Related]

  • 7. IL-34-Dependent Intrarenal and Systemic Mechanisms Promote Lupus Nephritis in MRL-Faslpr Mice.
    Wada Y, Gonzalez-Sanchez HM, Weinmann-Menke J, Iwata Y, Ajay AK, Meineck M, Kelley VR.
    J Am Soc Nephrol; 2019 Feb 15; 30(2):244-259. PubMed ID: 30622154
    [Abstract] [Full Text] [Related]

  • 8. Inducible co-stimulator null MRL-Faslpr mice: uncoupling of autoantibodies and T cell responses in lupus.
    Zeller GC, Hirahashi J, Schwarting A, Sharpe AH, Kelley VR.
    J Am Soc Nephrol; 2006 Jan 15; 17(1):122-30. PubMed ID: 16291836
    [Abstract] [Full Text] [Related]

  • 9. Correlation of renal tubular epithelial cell-derived interleukin-18 up-regulation with disease activity in MRL-Faslpr mice with autoimmune lupus nephritis.
    Faust J, Menke J, Kriegsmann J, Kelley VR, Mayet WJ, Galle PR, Schwarting A.
    Arthritis Rheum; 2002 Nov 15; 46(11):3083-95. PubMed ID: 12428253
    [Abstract] [Full Text] [Related]

  • 10. Upregulation of lymphoid and renal interferon-gamma mRNA in autoimmune MRL-Fas(lpr) mice with lupus nephritis.
    Fan X, Wüthrich RP.
    Inflammation; 1997 Feb 15; 21(1):105-12. PubMed ID: 9179626
    [Abstract] [Full Text] [Related]

  • 11. Targeting transcription factor Stat4 uncovers a role for interleukin-18 in the pathogenesis of severe lupus nephritis in mice.
    Menke J, Bork T, Kutska B, Byrne KT, Blanfeld M, Relle M, Kelley VR, Schwarting A.
    Kidney Int; 2011 Feb 15; 79(4):452-63. PubMed ID: 20980973
    [Abstract] [Full Text] [Related]

  • 12. CXCR3 mediates renal Th1 and Th17 immune response in murine lupus nephritis.
    Steinmetz OM, Turner JE, Paust HJ, Lindner M, Peters A, Heiss K, Velden J, Hopfer H, Fehr S, Krieger T, Meyer-Schwesinger C, Meyer TN, Helmchen U, Mittrücker HW, Stahl RA, Panzer U.
    J Immunol; 2009 Oct 01; 183(7):4693-704. PubMed ID: 19734217
    [Abstract] [Full Text] [Related]

  • 13. Autocrine production of IFN-gamma by macrophages controls their recruitment to kidney and the development of glomerulonephritis in MRL/lpr mice.
    Carvalho-Pinto CE, García MI, Mellado M, Rodríguez-Frade JM, Martín-Caballero J, Flores J, Martínez-A C, Balomenos D.
    J Immunol; 2002 Jul 15; 169(2):1058-67. PubMed ID: 12097414
    [Abstract] [Full Text] [Related]

  • 14. Blockade of IL-18 receptor signaling delays the onset of autoimmune disease in MRL-Faslpr mice.
    Kinoshita K, Yamagata T, Nozaki Y, Sugiyama M, Ikoma S, Funauchi M, Kanamaru A.
    J Immunol; 2004 Oct 15; 173(8):5312-8. PubMed ID: 15470078
    [Abstract] [Full Text] [Related]

  • 15. Aberrant macrophages mediate defective kidney repair that triggers nephritis in lupus-susceptible mice.
    Iwata Y, Boström EA, Menke J, Rabacal WA, Morel L, Wada T, Kelley VR.
    J Immunol; 2012 May 01; 188(9):4568-80. PubMed ID: 22467656
    [Abstract] [Full Text] [Related]

  • 16. B cells are required for lupus nephritis in the polygenic, Fas-intact MRL model of systemic autoimmunity.
    Chan OT, Madaio MP, Shlomchik MJ.
    J Immunol; 1999 Oct 01; 163(7):3592-6. PubMed ID: 10490951
    [Abstract] [Full Text] [Related]

  • 17. TNF-alpha enhances colony-stimulating factor-1-induced macrophage accumulation in autoimmune renal disease.
    Moore KJ, Yeh K, Naito T, Kelley VR.
    J Immunol; 1996 Jul 01; 157(1):427-32. PubMed ID: 8683148
    [Abstract] [Full Text] [Related]

  • 18. Up-regulation of tubular epithelial interleukin-12 in autoimmune MRL-Fas(lpr) mice with renal injury.
    Fan X, Oertli B, Wüthrich RP.
    Kidney Int; 1997 Jan 01; 51(1):79-86. PubMed ID: 8995720
    [Abstract] [Full Text] [Related]

  • 19. Nephritogenic cytokines and disease in MRL-Fas(lpr) kidneys are dependent on multiple T-cell subsets.
    Wada T, Schwarting A, Chesnutt MS, Wofsy D, Rubin Kelley V.
    Kidney Int; 2001 Feb 01; 59(2):565-78. PubMed ID: 11168938
    [Abstract] [Full Text] [Related]

  • 20. Costimulation by B7-1 and B7-2 is required for autoimmune disease in MRL-Faslpr mice.
    Kinoshita K, Tesch G, Schwarting A, Maron R, Sharpe AH, Kelley VR.
    J Immunol; 2000 Jun 01; 164(11):6046-56. PubMed ID: 10820290
    [Abstract] [Full Text] [Related]

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