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Journal Abstract Search

197 related items for PubMed ID: 12659423

  • 1. Synthesis and antitumor cytotoxicity evaluation of novel pyrrolo[2,1-c][1,4]benzodiazepine imidazole containing polyamide conjugates.
    Kumar R, Lown JW.
    Oncol Res; 2003; 13(4):221-33. PubMed ID: 12659423
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis and in vitro cytotoxic studies of novel bis-pyrrolo[2,1][1,4] benzodiazepine-pyrrole and imidazole polyamide conjugates.
    Kumar R, Lown JW.
    Eur J Med Chem; 2005 Jul; 40(7):641-54. PubMed ID: 15935899
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis and in vitro cytotoxicity studies of novel pyrrolo[2,1-c][1,4]benzodiazepine (PBD)--polymade conjugates and 2,2'-PBD dimers.
    Reddy BS, Damayanthi Y, Reddy BS, Lown JW.
    Anticancer Drug Des; 2000 Jun; 15(3):225-38. PubMed ID: 11049090
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis and in vitro cytotoxicity studies of novel pyrrolo [2,1][1,4] benzodiazepine-glycosylated pyrrole and imidazole polyamide conjugates.
    Kumar R, Lown JW.
    Org Biomol Chem; 2003 Oct 07; 1(19):3327-42. PubMed ID: 14584797
    [Abstract] [Full Text] [Related]

  • 5. Quinazolinone linked pyrrolo[2,1-c][1,4]benzodiazepine (PBD) conjugates: Design, synthesis and biological evaluation as potential anticancer agents.
    Kamal A, Vijaya Bharathi E, Janaki Ramaiah M, Dastagiri D, Surendranadha Reddy J, Viswanath A, Sultana F, Pushpavalli SN, Pal-Bhadra M, Srivastava HK, Narahari Sastry G, Juvekar A, Sen S, Zingde S.
    Bioorg Med Chem; 2010 Jan 15; 18(2):526-42. PubMed ID: 20031423
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and biological properties of sequence-specific DNA-alkylating pyrrole-imidazole polyamides.
    Bando T, Sugiyama H.
    Acc Chem Res; 2006 Dec 15; 39(12):935-44. PubMed ID: 17176032
    [Abstract] [Full Text] [Related]

  • 7. Synthesis of new benzimidazole linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates with efficient DNA-binding affinity and potent cytotoxicity.
    Kamal A, Kumar PP, Sreekanth K, Seshadri BN, Ramulu P.
    Bioorg Med Chem Lett; 2008 Apr 15; 18(8):2594-8. PubMed ID: 18378445
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis, and biological evaluation of pyrrolo[2,1-c][1,4]benzodiazepine and indole conjugates as anticancer agents.
    Wang JJ, Shen YK, Hu WP, Hsieh MC, Lin FL, Hsu MK, Hsu MH.
    J Med Chem; 2006 Feb 23; 49(4):1442-9. PubMed ID: 16480280
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and biological evaluation of pyrrolo[2,1-c][1,4]benzodiazepine (PBD) C8 cyclic amine conjugates.
    Masterson LA, Croker SJ, Jenkins TC, Howard PW, Thurston DE.
    Bioorg Med Chem Lett; 2004 Feb 23; 14(4):901-4. PubMed ID: 15012990
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and in vitro cytotoxicity studies of novel L-tryptophan-polyamide conjugates and L-tryptophan dimers linked with aliphatic chains and polyamides.
    Kumar R, Rai D, Lown JW.
    Oncol Res; 2004 Feb 23; 14(4-5):247-65. PubMed ID: 14977356
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and biological evaluation of estradiol linked pyrrolo[2,1-c][1,4]benzodiazepine (PBD) conjugates as potential anticancer agents.
    Kamal A, Reddy MK, Ramaiah MJ, Rajender, Reddy JS, Srikanth YV, Dastagiri D, Bharathi EV, Pushpavalli SN, Sarma P, Pal-Bhadra M.
    Bioorg Med Chem; 2011 Apr 15; 19(8):2565-81. PubMed ID: 21459581
    [Abstract] [Full Text] [Related]

  • 12. Synthesis of C8-linked pyrrolo[2,1-c][1,4]benzodiazepine-benzimidazole conjugates with remarkable DNA-binding affinity.
    Kamal A, Ramulu P, Srinivas O, Ramesh G, Kumar PP.
    Bioorg Med Chem Lett; 2004 Sep 20; 14(18):4791-4. PubMed ID: 15324909
    [Abstract] [Full Text] [Related]

  • 13. Linker length modulates DNA cross-linking reactivity and cytotoxic potency of C8/C8' ether-linked C2-exo-unsaturated pyrrolo[2,1-c][1,4]benzodiazepine (PBD) dimers.
    Gregson SJ, Howard PW, Gullick DR, Hamaguchi A, Corcoran KE, Brooks NA, Hartley JA, Jenkins TC, Patel S, Guille MJ, Thurston DE.
    J Med Chem; 2004 Feb 26; 47(5):1161-74. PubMed ID: 14971896
    [Abstract] [Full Text] [Related]

  • 14. Phosphonate-linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates: synthesis, DNA-binding affinity and cytotoxicity.
    Kamal A, Kumar PP, Seshadri BN, Srinivas O, Kumar MS, Sen S, Kurian N, Juvekar AS, Zingde SM.
    Bioorg Med Chem; 2008 Apr 01; 16(7):3895-906. PubMed ID: 18262426
    [Abstract] [Full Text] [Related]

  • 15. Solid-phase synthesis of new pyrrolobenzodiazepine-chalcone conjugates: DNA-binding affinity and anticancer activity.
    Kamal A, Shankaraiah N, Prabhakar S, Reddy ChR, Markandeya N, Reddy KL, Devaiah V.
    Bioorg Med Chem Lett; 2008 Apr 01; 18(7):2434-9. PubMed ID: 18325766
    [Abstract] [Full Text] [Related]

  • 16. Recent developments in novel pyrrolo[2,1-c][1,4]benzodiazepine conjugates: synthesis and biological evaluation.
    Kumar R, Lown JW.
    Mini Rev Med Chem; 2003 Jun 01; 3(4):323-39. PubMed ID: 12678826
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and biological properties of pyrrole-imidazole polyamide conjugates.
    Minoshima M, Sasaki S, Fujimoto J, Shinohara K, Bando T, Sugiyama H.
    Nucleic Acids Symp Ser (Oxf); 2007 Jun 01; (51):35-6. PubMed ID: 18029573
    [Abstract] [Full Text] [Related]

  • 18. Anticancer activities of alkylating pyrrole-imidazole polyamides with specific sequence recognition.
    Shinohara K, Bando T, Sugiyama H.
    Anticancer Drugs; 2010 Mar 01; 21(3):228-42. PubMed ID: 20038830
    [Abstract] [Full Text] [Related]

  • 19. A novel class of achiral seco-analogs of CC-1065 and the duocarmycins: design, synthesis, DNA binding, and anticancer properties.
    Kupchinsky S, Centioni S, Howard T, Trzupek J, Roller S, Carnahan V, Townes H, Purnell B, Price C, Handl H, Summerville K, Johnson K, Toth J, Hudson S, Kiakos K, Hartley JA, Lee M.
    Bioorg Med Chem; 2004 Dec 01; 12(23):6221-36. PubMed ID: 15519165
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis, and in vitro antitumor activity of new 1,4-diarylimidazole-2-ones and their 2-thione analogues.
    Congiu C, Cocco MT, Onnis V.
    Bioorg Med Chem Lett; 2008 Feb 01; 18(3):989-93. PubMed ID: 18164978
    [Abstract] [Full Text] [Related]

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