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213 related items for PubMed ID: 12667087

  • 1. The mechanism of Ras GTPase activation by neurofibromin.
    Phillips RA, Hunter JL, Eccleston JF, Webb MR.
    Biochemistry; 2003 Apr 08; 42(13):3956-65. PubMed ID: 12667087
    [Abstract] [Full Text] [Related]

  • 2. Mechanism of the guanine nucleotide exchange reaction of Ras GTPase--evidence for a GTP/GDP displacement model.
    Zhang B, Zhang Y, Shacter E, Zheng Y.
    Biochemistry; 2005 Feb 22; 44(7):2566-76. PubMed ID: 15709769
    [Abstract] [Full Text] [Related]

  • 3. Real-time in vitro measurement of intrinsic and Ras GAP-mediated GTP hydrolysis.
    Shutes A, Der CJ.
    Methods Enzymol; 2006 Feb 22; 407():9-22. PubMed ID: 16757310
    [Abstract] [Full Text] [Related]

  • 4. Individual rate constants for the interaction of Ras proteins with GTPase-activating proteins determined by fluorescence spectroscopy.
    Ahmadian MR, Hoffmann U, Goody RS, Wittinghofer A.
    Biochemistry; 1997 Apr 15; 36(15):4535-41. PubMed ID: 9109662
    [Abstract] [Full Text] [Related]

  • 5. Mechanism of GTP hydrolysis by p21N-ras catalyzed by GAP: studies with a fluorescent GTP analogue.
    Moore KJ, Webb MR, Eccleston JF.
    Biochemistry; 1993 Jul 27; 32(29):7451-9. PubMed ID: 8338843
    [Abstract] [Full Text] [Related]

  • 6. The kinetic mechanism of the GAP-activated GTPase of p21 ras.
    Moore KJ, Lowe PN, Eccleston JF.
    Philos Trans R Soc Lond B Biol Sci; 1992 Apr 29; 336(1276):49-53; discussion 53-4. PubMed ID: 1351296
    [Abstract] [Full Text] [Related]

  • 7. Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras.
    Schweins T, Geyer M, Kalbitzer HR, Wittinghofer A, Warshel A.
    Biochemistry; 1996 Nov 12; 35(45):14225-31. PubMed ID: 8916907
    [Abstract] [Full Text] [Related]

  • 8. Mechanisms of guanosine triphosphate hydrolysis by Ras and Ras-GAP proteins as rationalized by ab initio QM/MM simulations.
    Grigorenko BL, Nemukhin AV, Shadrina MS, Topol IA, Burt SK.
    Proteins; 2007 Feb 01; 66(2):456-66. PubMed ID: 17094109
    [Abstract] [Full Text] [Related]

  • 9. Phosphate release during microtubule assembly: what stabilizes growing microtubules?
    Vandecandelaere A, Brune M, Webb MR, Martin SR, Bayley PM.
    Biochemistry; 1999 Jun 22; 38(25):8179-88. PubMed ID: 10387063
    [Abstract] [Full Text] [Related]

  • 10. Differences in the interaction of p21c-Ha-ras-GMP-PNP with full-length neurofibromin and GTPase-activating protein.
    DiBattiste D, Golubic M, Stacey D, Wolfman A.
    Oncogene; 1993 Mar 22; 8(3):637-43. PubMed ID: 8437847
    [Abstract] [Full Text] [Related]

  • 11. Fluorescence methods in the study of small GTP-binding proteins.
    Ahmadian MR, Wittinghofer A, Herrmann C.
    Methods Mol Biol; 2002 Mar 22; 189():45-63. PubMed ID: 12094594
    [No Abstract] [Full Text] [Related]

  • 12. Time-resolved FTIR studies of the GTPase reaction of H-ras p21 reveal a key role for the beta-phosphate.
    Cepus V, Scheidig AJ, Goody RS, Gerwert K.
    Biochemistry; 1998 Jul 14; 37(28):10263-71. PubMed ID: 9665734
    [Abstract] [Full Text] [Related]

  • 13. How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.
    Ghosh A, Praefcke GJ, Renault L, Wittinghofer A, Herrmann C.
    Nature; 2006 Mar 02; 440(7080):101-4. PubMed ID: 16511497
    [Abstract] [Full Text] [Related]

  • 14. Raman difference studies of GDP and GTP binding to c-Harvey ras.
    Wang JH, Xiao DG, Deng H, Webb MR, Callender R.
    Biochemistry; 1998 Aug 04; 37(31):11106-16. PubMed ID: 9693007
    [Abstract] [Full Text] [Related]

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  • 17. The role of the metal ion in the p21ras catalysed GTP-hydrolysis: Mn2+ versus Mg2+.
    Schweins T, Scheffzek K, Assheuer R, Wittinghofer A.
    J Mol Biol; 1997 Mar 07; 266(4):847-56. PubMed ID: 9102473
    [Abstract] [Full Text] [Related]

  • 18. Roles of G(o)alpha tryptophans in GTP hydrolysis, GDP release, and fluorescence signals.
    Lan KL, Remmers AE, Neubig RR.
    Biochemistry; 1998 Jan 20; 37(3):837-43. PubMed ID: 9454573
    [Abstract] [Full Text] [Related]

  • 19. Dissection of the GTPase mechanism of Ras protein by MD analysis of Ras mutants.
    Friedman ZY, Devary Y.
    Proteins; 2005 May 15; 59(3):528-33. PubMed ID: 15789417
    [Abstract] [Full Text] [Related]

  • 20. GTP hydrolysis mechanisms in ras p21 and in the ras-GAP complex studied by fluorescence measurements on tryptophan mutants.
    Antonny B, Chardin P, Roux M, Chabre M.
    Biochemistry; 1991 Aug 27; 30(34):8287-95. PubMed ID: 1883817
    [Abstract] [Full Text] [Related]

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