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862 related items for PubMed ID: 12670894

  • 1. Bax plays a pivotal role in thapsigargin-induced apoptosis of human colon cancer HCT116 cells by controlling Smac/Diablo and Omi/HtrA2 release from mitochondria.
    Yamaguchi H, Bhalla K, Wang HG.
    Cancer Res; 2003 Apr 01; 63(7):1483-9. PubMed ID: 12670894
    [Abstract] [Full Text] [Related]

  • 2. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.
    Kandasamy K, Srinivasula SM, Alnemri ES, Thompson CB, Korsmeyer SJ, Bryant JL, Srivastava RK.
    Cancer Res; 2003 Apr 01; 63(7):1712-21. PubMed ID: 12670926
    [Abstract] [Full Text] [Related]

  • 3. Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-x(L) in a strictly caspase-3-dependent manner in human carcinoma cells.
    Hasenjäger A, Gillissen B, Müller A, Normand G, Hemmati PG, Schuler M, Dörken B, Daniel PT.
    Oncogene; 2004 Jun 03; 23(26):4523-35. PubMed ID: 15064710
    [Abstract] [Full Text] [Related]

  • 4. Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.
    Wu SJ, Ng LT, Lin CC.
    Eur J Pharmacol; 2005 Aug 22; 518(2-3):96-106. PubMed ID: 16054126
    [Abstract] [Full Text] [Related]

  • 5. Phytosphingosine induces apoptotic cell death via caspase 8 activation and Bax translocation in human cancer cells.
    Park MT, Kang JA, Choi JA, Kang CM, Kim TH, Bae S, Kang S, Kim S, Choi WI, Cho CK, Chung HY, Lee YS, Lee SJ.
    Clin Cancer Res; 2003 Feb 22; 9(2):878-85. PubMed ID: 12576463
    [Abstract] [Full Text] [Related]

  • 6. Role of mitochondria in aspirin-induced apoptosis in human gastric epithelial cells.
    Redlak MJ, Power JJ, Miller TA.
    Am J Physiol Gastrointest Liver Physiol; 2005 Oct 22; 289(4):G731-8. PubMed ID: 15976387
    [Abstract] [Full Text] [Related]

  • 7. Role of caspases in Ox-LDL-induced apoptotic cascade in human coronary artery endothelial cells.
    Chen J, Mehta JL, Haider N, Zhang X, Narula J, Li D.
    Circ Res; 2004 Feb 20; 94(3):370-6. PubMed ID: 14684629
    [Abstract] [Full Text] [Related]

  • 8. Real-time single cell analysis of Smac/DIABLO release during apoptosis.
    Rehm M, Düssmann H, Prehn JH.
    J Cell Biol; 2003 Sep 15; 162(6):1031-43. PubMed ID: 12975347
    [Abstract] [Full Text] [Related]

  • 9. Effect of Bax deficiency on death receptor 5 and mitochondrial pathways during endoplasmic reticulum calcium pool depletion-induced apoptosis.
    He Q, Montalbano J, Corcoran C, Jin W, Huang Y, Sheikh MS.
    Oncogene; 2003 May 01; 22(17):2674-9. PubMed ID: 12730681
    [Abstract] [Full Text] [Related]

  • 10. Cadmium induces apoptotic cell death in WI 38 cells via caspase-dependent Bid cleavage and calpain-mediated mitochondrial Bax cleavage by Bcl-2-independent pathway.
    Oh SH, Lee BH, Lim SC.
    Biochem Pharmacol; 2004 Nov 01; 68(9):1845-55. PubMed ID: 15450950
    [Abstract] [Full Text] [Related]

  • 11. Bisphenol A diglycidyl ether-induced apoptosis involves Bax/Bid-dependent mitochondrial release of apoptosis-inducing factor (AIF), cytochrome c and Smac/DIABLO.
    Fehlberg S, Gregel CM, Göke A, Göke R.
    Br J Pharmacol; 2003 Jun 01; 139(3):495-500. PubMed ID: 12788809
    [Abstract] [Full Text] [Related]

  • 12. Reactive oxygen species regulate caspase activation in tumor necrosis factor-related apoptosis-inducing ligand-resistant human colon carcinoma cell lines.
    Izeradjene K, Douglas L, Tillman DM, Delaney AB, Houghton JA.
    Cancer Res; 2005 Aug 15; 65(16):7436-45. PubMed ID: 16103097
    [Abstract] [Full Text] [Related]

  • 13. Impaired kinetics of Bax-GFP and Smac/DIABLO-GFP in caspase-8- and bid-silenced and Bcl-2 overexpressed breast cancer MCF-7 cells exposed to camptothecin.
    Górka M, Lamparska-Przybysz M, Motyl T.
    Cell Mol Biol (Noisy-le-grand); 2007 Jan 21; 52 Suppl():OL915-22. PubMed ID: 17666167
    [Abstract] [Full Text] [Related]

  • 14. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria.
    Zhang XD, Zhang XY, Gray CP, Nguyen T, Hersey P.
    Cancer Res; 2001 Oct 01; 61(19):7339-48. PubMed ID: 11585775
    [Abstract] [Full Text] [Related]

  • 15. RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells involves Bax translocation to mitochondria.
    Yu W, Sanders BG, Kline K.
    Cancer Res; 2003 May 15; 63(10):2483-91. PubMed ID: 12750270
    [Abstract] [Full Text] [Related]

  • 16. Human colon cancer cells lacking Bax resist curcumin-induced apoptosis and Bax requirement is dispensable with ectopic expression of Smac or downregulation of Bcl-XL.
    Rashmi R, Kumar S, Karunagaran D.
    Carcinogenesis; 2005 Apr 15; 26(4):713-23. PubMed ID: 15661804
    [Abstract] [Full Text] [Related]

  • 17. Cephalostatin 1 selectively triggers the release of Smac/DIABLO and subsequent apoptosis that is characterized by an increased density of the mitochondrial matrix.
    Dirsch VM, Müller IM, Eichhorst ST, Pettit GR, Kamano Y, Inoue M, Xu JP, Ichihara Y, Wanner G, Vollmar AM.
    Cancer Res; 2003 Dec 15; 63(24):8869-76. PubMed ID: 14695204
    [Abstract] [Full Text] [Related]

  • 18. Hierarchical recruitment by AMPA but not staurosporine of pro-apoptotic mitochondrial signaling in cultured cortical neurons: evidence for caspase-dependent/independent cross-talk.
    Beart PM, Lim ML, Chen B, Diwakarla S, Mercer LD, Cheung NS, Nagley P.
    J Neurochem; 2007 Dec 15; 103(6):2408-27. PubMed ID: 17887970
    [Abstract] [Full Text] [Related]

  • 19. Endogenously released Smac is insufficient to mediate cell death of human lung carcinoma in response to etoposide.
    Bartling B, Lewensohn R, Zhivotovsky B.
    Exp Cell Res; 2004 Aug 01; 298(1):83-95. PubMed ID: 15242764
    [Abstract] [Full Text] [Related]

  • 20. c-IAP1 blocks TNFalpha-mediated cytotoxicity upstream of caspase-dependent and -independent mitochondrial events in human leukemic cells.
    Partheniou F, Kelsey SM, Srinivasula SM, Newland AC, Alnemri ES, Jia L.
    Biochem Biophys Res Commun; 2001 Sep 14; 287(1):181-9. PubMed ID: 11549272
    [Abstract] [Full Text] [Related]

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