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Journal Abstract Search

231 related items for PubMed ID: 12672251

  • 1.
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  • 2. Prazosin-related compounds. Effect of transforming the piperazinylquinazoline moiety into an aminomethyltetrahydroacridine system on the affinity for alpha1-adrenoreceptors.
    Rosini M, Antonello A, Cavalli A, Bolognesi ML, Minarini A, Marucci G, Poggesi E, Leonardi A, Melchiorre C.
    J Med Chem; 2003 Nov 06; 46(23):4895-903. PubMed ID: 14584940
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  • 5. 1,3-Dioxolane-based ligands as rigid analogues of naftopidil: structure-affinity/activity relationships at alpha1 and 5-HT1A receptors.
    Sorbi C, Franchini S, Tait A, Prandi A, Gallesi R, Angeli P, Marucci G, Pirona L, Poggesi E, Brasili L.
    ChemMedChem; 2009 Mar 06; 4(3):393-9. PubMed ID: 19152363
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  • 7. Structure-activity relationships in 1,4-benzodioxan-related compounds. 7. Selectivity of 4-phenylchroman analogues for alpha(1)-adrenoreceptor subtypes.
    Quaglia W, Pigini M, Piergentili A, Giannella M, Gentili F, Marucci G, Carrieri A, Carotti A, Poggesi E, Leonardi A, Melchiorre C.
    J Med Chem; 2002 Apr 11; 45(8):1633-43. PubMed ID: 11931617
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  • 9. Synthesis and structure-activity relationship of fluoro analogues of 8-{2-[4-(4-methoxyphenyl)piperazin-1yl]ethyl}-8-azaspiro[4.5]decane-7,9-dione as selective alpha(1d)-adrenergic receptor antagonists.
    Konkel MJ, Wetzel JM, Cahir M, Craig DA, Noble SA, Gluchowski C.
    J Med Chem; 2005 Apr 21; 48(8):3076-9. PubMed ID: 15828846
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and alpha(1)-adrenoceptor antagonist activity of derivatives and isosters of the furan portion of (+)-cyclazosin.
    Sagratini G, Angeli P, Buccioni M, Gulini U, Marucci G, Melchiorre C, Leonardi A, Poggesi E, Giardinà D.
    Bioorg Med Chem; 2007 Mar 15; 15(6):2334-45. PubMed ID: 17276073
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  • 11. RBx 6198: a novel alpha1-adrenoceptor antagonist for the treatment of benign prostatic hyperplasia.
    Nanda K, Naruganahalli KS, Gupta S, Malhotra S, Tiwari A, Hegde LG, Jain S, Sinha N, Gupta JB, Chugh A, Anand N, Ray A.
    Eur J Pharmacol; 2009 Apr 01; 607(1-3):213-9. PubMed ID: 19239913
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  • 12. New potential uroselective NO-donor alpha1-antagonists.
    Boschi D, Tron GC, Di Stilo A, Fruttero R, Gasco A, Poggesi E, Motta G, Leonardi A.
    J Med Chem; 2003 Aug 14; 46(17):3762-5. PubMed ID: 12904082
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  • 13. 8-NH2-boldine, an antagonist of alpha1A and alpha1B adrenoceptors without affinity for the alpha1D subtype: structural requirements for aporphines at alpha1-adrenoceptor subtypes.
    Ivorra MD, Valiente M, Martínez S, Madrero Y, Noguera MA, Cassels BK, Sobarzo EM, D'Ocon P.
    Planta Med; 2005 Oct 14; 71(10):897-903. PubMed ID: 16254819
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  • 14. Synthesis, absolute configuration, and biological profile of the enantiomers of trans-[2-(2,6-dimethoxyphenoxy)ethyl] [(3-p-tolyl-2,3-dihydro-1,4-benzodioxin-2-yl)methyl]amine (mephendioxan), a potent competitive alpha 1A-adrenoreceptor antagonist.
    Quaglia W, Pigini M, Tayebati SK, Piergentili A, Giannella M, Leonardi A, Taddei C, Melchiorre C.
    J Med Chem; 1996 May 24; 39(11):2253-8. PubMed ID: 8667368
    [Abstract] [Full Text] [Related]

  • 15. WB 4101-related compounds. 2. Role of the ethylene chain separating amine and phenoxy units on the affinity for alpha(1)-adrenoreceptor subtypes and 5-HT(1A) receptors.
    Bolognesi ML, Budriesi R, Cavalli A, Chiarini A, Gotti R, Leonardi A, Minarini A, Poggesi E, Recanatini M, Rosini M, Tumiatti V, Melchiorre C.
    J Med Chem; 1999 Oct 07; 42(20):4214-24. PubMed ID: 10514291
    [Abstract] [Full Text] [Related]

  • 16. Synthesis, biological evaluation, and docking studies of tetrahydrofuran- cyclopentanone- and cyclopentanol-based ligands acting at adrenergic α₁- and serotonine 5-HT1A receptors.
    Prandi A, Franchini S, Manasieva LI, Fossa P, Cichero E, Marucci G, Buccioni M, Cilia A, Pirona L, Brasili L.
    J Med Chem; 2012 Jan 12; 55(1):23-36. PubMed ID: 22145629
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  • 18. Novel adrenoceptor antagonists with a tricyclic pyrrolodipyridazine skeleton.
    Barlocco D, Cignarella G, Montesano F, Leonardi A, Mella M, Toma L.
    J Med Chem; 1999 Jan 14; 42(1):173-7. PubMed ID: 9888842
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  • 19. RS-17053 (N-[2-(2-cyclopropylmethoxyphenoxy)ethyl]-5-chloro-alpha, alpha-dimethyl-1H-indole-3-ethanamine hydrochloride), a selective alpha 1A-adrenoceptor antagonist, displays low affinity for functional alpha 1-adrenoceptors in human prostate: implications for adrenoceptor classification.
    Ford AP, Arredondo NF, Blue DR, Bonhaus DW, Jasper J, Kava MS, Lesnick J, Pfister JR, Shieh IA, Vimont RL, Williams TJ, McNeal JE, Stamey TA, Clarke DE.
    Mol Pharmacol; 1996 Feb 14; 49(2):209-15. PubMed ID: 8632751
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