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426 related items for PubMed ID: 12673208

  • 1. Synergistic induction of tumor cell apoptosis by death receptor antibody and chemotherapy agent through JNK/p38 and mitochondrial death pathway.
    Ohtsuka T, Buchsbaum D, Oliver P, Makhija S, Kimberly R, Zhou T.
    Oncogene; 2003 Apr 03; 22(13):2034-44. PubMed ID: 12673208
    [Abstract] [Full Text] [Related]

  • 2. Bisindolylmaleimide VIII enhances DR5-mediated apoptosis through the MKK4/JNK/p38 kinase and the mitochondrial pathways.
    Ohtsuka T, Zhou T.
    J Biol Chem; 2002 Aug 09; 277(32):29294-303. PubMed ID: 12034736
    [Abstract] [Full Text] [Related]

  • 3. Chemotherapeutic agents sensitize sarcoma cell lines to tumor necrosis factor-related apoptosis-inducing ligand-induced caspase-8 activation, apoptosis and loss of mitochondrial membrane potential.
    Hotta T, Suzuki H, Nagai S, Yamamoto K, Imakiire A, Takada E, Itoh M, Mizuguchi J.
    J Orthop Res; 2003 Sep 09; 21(5):949-57. PubMed ID: 12919886
    [Abstract] [Full Text] [Related]

  • 4. Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop.
    von Haefen C, Wieder T, Essmann F, Schulze-Osthoff K, Dörken B, Daniel PT.
    Oncogene; 2003 Apr 17; 22(15):2236-47. PubMed ID: 12700660
    [Abstract] [Full Text] [Related]

  • 5. Pharmacologic mitogen-activated protein/extracellular signal-regulated kinase kinase/mitogen-activated protein kinase inhibitors interact synergistically with STI571 to induce apoptosis in Bcr/Abl-expressing human leukemia cells.
    Yu C, Krystal G, Varticovksi L, McKinstry R, Rahmani M, Dent P, Grant S.
    Cancer Res; 2002 Jan 01; 62(1):188-99. PubMed ID: 11782377
    [Abstract] [Full Text] [Related]

  • 6. Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and receptor-mediated apoptosis.
    Saeki K, Kobayashi N, Inazawa Y, Zhang H, Nishitoh H, Ichijo H, Saeki K, Isemura M, Yuo A.
    Biochem J; 2002 Dec 15; 368(Pt 3):705-20. PubMed ID: 12206715
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of JNK signaling diminishes early but not late cellular stress-induced apoptosis.
    Krilleke D, Ucur E, Pulte D, Schulze-Osthoff K, Debatin KM, Herr I.
    Int J Cancer; 2003 Nov 20; 107(4):520-7. PubMed ID: 14520687
    [Abstract] [Full Text] [Related]

  • 8. Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8.
    Söderström TS, Poukkula M, Holmström TH, Heiskanen KM, Eriksson JE.
    J Immunol; 2002 Sep 15; 169(6):2851-60. PubMed ID: 12218097
    [Abstract] [Full Text] [Related]

  • 9. LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via hydrogen peroxide-mediated mitogen-activated protein kinase activation and up-regulation of death receptors.
    Shenoy K, Wu Y, Pervaiz S.
    Cancer Res; 2009 Mar 01; 69(5):1941-50. PubMed ID: 19223550
    [Abstract] [Full Text] [Related]

  • 10. Taxol-induced mitochondrial stress in melanoma cells is mediated by activation of c-Jun N-terminal kinase (JNK) and p38 pathways via uncoupling protein 2.
    Selimovic D, Hassan M, Haikel Y, Hengge UR.
    Cell Signal; 2008 Feb 01; 20(2):311-22. PubMed ID: 18068334
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of extracellular signal-regulated kinase (ERK) mediates cell cycle phase independent apoptosis in vinblastine-treated ML-1 cells.
    Stadheim TA, Xiao H, Eastman A.
    Cancer Res; 2001 Feb 15; 61(4):1533-40. PubMed ID: 11245462
    [Abstract] [Full Text] [Related]

  • 12. c-Myc potentiates the mitochondrial pathway of apoptosis by acting upstream of apoptosis signal-regulating kinase 1 (Ask1) in the p38 signalling cascade.
    Desbiens KM, Deschesnes RG, Labrie MM, Desfossés Y, Lambert H, Landry J, Bellmann K.
    Biochem J; 2003 Jun 01; 372(Pt 2):631-41. PubMed ID: 12646044
    [Abstract] [Full Text] [Related]

  • 13. Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium.
    Chuang SM, Wang IC, Yang JL.
    Carcinogenesis; 2000 Jul 01; 21(7):1423-32. PubMed ID: 10874022
    [Abstract] [Full Text] [Related]

  • 14. Synergy is achieved by complementation with Apo2L/TRAIL and actinomycin D in Apo2L/TRAIL-mediated apoptosis of prostate cancer cells: role of XIAP in resistance.
    Ng CP, Zisman A, Bonavida B.
    Prostate; 2002 Dec 01; 53(4):286-99. PubMed ID: 12430140
    [Abstract] [Full Text] [Related]

  • 15. Role of MAP kinases and their cross-talk in TGF-beta1-induced apoptosis in FaO rat hepatoma cell line.
    Park HJ, Kim BC, Kim SJ, Choi KS.
    Hepatology; 2002 Jun 01; 35(6):1360-71. PubMed ID: 12029621
    [Abstract] [Full Text] [Related]

  • 16. JNK (c-Jun N-terminal kinase) and p38 activation in receptor-mediated and chemically-induced apoptosis of T-cells: differential requirements for caspase activation.
    MacFarlane M, Cohen GM, Dickens M.
    Biochem J; 2000 May 15; 348 Pt 1(Pt 1):93-101. PubMed ID: 10794718
    [Abstract] [Full Text] [Related]

  • 17. Microtubule inhibitors elicit differential effects on MAP kinase (JNK, ERK, and p38) signaling pathways in human KB-3 carcinoma cells.
    Stone AA, Chambers TC.
    Exp Cell Res; 2000 Jan 10; 254(1):110-9. PubMed ID: 10623471
    [Abstract] [Full Text] [Related]

  • 18. Synergistic induction of apoptosis by the combination of trail and chemotherapy in chemoresistant ovarian cancer cells.
    Cuello M, Ettenberg SA, Nau MM, Lipkowitz S.
    Gynecol Oncol; 2001 Jun 10; 81(3):380-90. PubMed ID: 11371126
    [Abstract] [Full Text] [Related]

  • 19. Ultraviolet-irradiation-induced apoptosis is mediated via ligand independent activation of tumor necrosis factor receptor 1.
    Sheikh MS, Antinore MJ, Huang Y, Fornace AJ.
    Oncogene; 1998 Nov 19; 17(20):2555-63. PubMed ID: 9840918
    [Abstract] [Full Text] [Related]

  • 20. The hierarchical relationship between MAPK signaling and ROS generation in human leukemia cells undergoing apoptosis in response to the proteasome inhibitor Bortezomib.
    Yu C, Rahmani M, Dent P, Grant S.
    Exp Cell Res; 2004 May 01; 295(2):555-66. PubMed ID: 15093752
    [Abstract] [Full Text] [Related]

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