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234 related items for PubMed ID: 12673674

  • 1. Farnesyl transferase inhibitor SCH66336 is cytostatic, pro-apoptotic and enhances chemosensitivity to cisplatin in melanoma cells.
    Smalley KS, Eisen TG.
    Int J Cancer; 2003 Jun 10; 105(2):165-75. PubMed ID: 12673674
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  • 3. Farnesyl thiosalicylic acid inhibits the growth of melanoma cells through a combination of cytostatic and pro-apoptotic effects.
    Smalley KS, Eisen TG.
    Int J Cancer; 2002 Apr 01; 98(4):514-22. PubMed ID: 11920610
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  • 4. Activity of the farnesyl protein transferase inhibitor SCH66336 against BCR/ABL-induced murine leukemia and primary cells from patients with chronic myeloid leukemia.
    Peters DG, Hoover RR, Gerlach MJ, Koh EY, Zhang H, Choe K, Kirschmeier P, Bishop WR, Daley GQ.
    Blood; 2001 Mar 01; 97(5):1404-12. PubMed ID: 11222387
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  • 6. Implication of protein kinase B/Akt and Bcl-2/Bcl-XL suppression by the farnesyl transferase inhibitor SCH66336 in apoptosis induction in squamous carcinoma cells.
    Chun KH, Lee HY, Hassan K, Khuri F, Hong WK, Lotan R.
    Cancer Res; 2003 Aug 15; 63(16):4796-800. PubMed ID: 12941797
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  • 7. Synergy of the protein farnesyltransferase inhibitor SCH66336 and cisplatin in human cancer cell lines.
    Adjei AA, Davis JN, Bruzek LM, Erlichman C, Kaufmann SH.
    Clin Cancer Res; 2001 May 15; 7(5):1438-45. PubMed ID: 11350915
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  • 10. Characterization of a human carcinoma cell line selected for resistance to the farnesyl transferase inhibitor 4-(2-(4-(8-chloro-3,10-dibromo-6,11-dihydro-5H-benzo-(5,6)-cyclohepta(1,2-b)-pyridin-11(R)-yl)-1-piperidinyl)-2-oxo-ethyl)-1-piperidinecarboxamide (SCH66336).
    Bruzek LM, Poynter JN, Kaufmann SH, Adjei AA.
    Mol Pharmacol; 2005 Aug 15; 68(2):477-86. PubMed ID: 15901852
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  • 12. Inhibition of cell growth in human glioblastoma cell lines by farnesyltransferase inhibitor SCH66336.
    Glass TL, Liu TJ, Yung WK.
    Neuro Oncol; 2000 Jul 15; 2(3):151-8. PubMed ID: 11302335
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  • 13. The farnesyl transferase inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling. Role in FTI enhancement of taxane and tamoxifen anti-tumor activity.
    Basso AD, Mirza A, Liu G, Long BJ, Bishop WR, Kirschmeier P.
    J Biol Chem; 2005 Sep 02; 280(35):31101-8. PubMed ID: 16006564
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  • 20. The farnesyl transferase inhibitor SCH 66336 induces a G(2) --> M or G(1) pause in sensitive human tumor cell lines.
    Ashar HR, James L, Gray K, Carr D, McGuirk M, Maxwell E, Black S, Armstrong L, Doll RJ, Taveras AG, Bishop WR, Kirschmeier P.
    Exp Cell Res; 2001 Jan 01; 262(1):17-27. PubMed ID: 11120601
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