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165 related items for PubMed ID: 12673781

  • 1. Polyol pathway and protein kinase C activity of rat Schwannoma cells.
    Kamiya H, Nakamura J, Hamada Y, Nakashima E, Naruse K, Kato K, Yasuda Y, Hotta N.
    Diabetes Metab Res Rev; 2003; 19(2):131-9. PubMed ID: 12673781
    [Abstract] [Full Text] [Related]

  • 2. Glucose-induced hyperproliferation of cultured rat aortic smooth muscle cells through polyol pathway hyperactivity.
    Nakamura J, Kasuya Y, Hamada Y, Nakashima E, Naruse K, Yasuda Y, Kato K, Hotta N.
    Diabetologia; 2001 Apr; 44(4):480-7. PubMed ID: 11357479
    [Abstract] [Full Text] [Related]

  • 3. High glucose-induced mesangial cell altered contractility: role of the polyol pathway.
    Derylo B, Babazono T, Glogowski E, Kapor-Drezgic J, Hohman T, Whiteside C.
    Diabetologia; 1998 May; 41(5):507-15. PubMed ID: 9628266
    [Abstract] [Full Text] [Related]

  • 4. High glucose-induced activation of the polyol pathway and changes of gene expression profiles in immortalized adult mouse Schwann cells IMS32.
    Sango K, Suzuki T, Yanagisawa H, Takaku S, Hirooka H, Tamura M, Watabe K.
    J Neurochem; 2006 Jul; 98(2):446-58. PubMed ID: 16805838
    [Abstract] [Full Text] [Related]

  • 5. Erythrocyte sorbitol level as a predictor of the efficacy of epalrestat treatment for diabetic peripheral polyneuropathy.
    Ando H, Takamura T, Nagai Y, Kaneko S, Kanazawa University Multicenter Diabetes Study Group.
    J Diabetes Complications; 2006 Jul; 20(6):367-70. PubMed ID: 17070440
    [Abstract] [Full Text] [Related]

  • 6. Therapeutic effects of aldose reductase inhibitor on experimental diabetic neuropathy through synthesis/secretion of nerve growth factor.
    Ohi T, Saita K, Furukawa S, Ohta M, Hayashi K, Matsukura S.
    Exp Neurol; 1998 Jun; 151(2):215-20. PubMed ID: 9628756
    [Abstract] [Full Text] [Related]

  • 7. An aldose reductase inhibitor prevents the glucose-induced increase in PDGF-beta receptor in cultured rat aortic smooth muscle cells.
    Kasuya Y, Nakamura J, Hamada Y, Nakayama M, Sasaki H, Komori T, Chaya S, Watanabe G, Naruse K, Nakashima E, Kato K, Hotta N.
    Biochem Biophys Res Commun; 1999 Aug 11; 261(3):853-8. PubMed ID: 10441515
    [Abstract] [Full Text] [Related]

  • 8. The aldose reductase inhibitor epalrestat exerts nephritic protection on diabetic nephropathy in db/db mice through metabolic modulation.
    He J, Gao HX, Yang N, Zhu XD, Sun RB, Xie Y, Zeng CH, Zhang JW, Wang JK, Ding F, Aa JY, Wang GJ.
    Acta Pharmacol Sin; 2019 Jan 11; 40(1):86-97. PubMed ID: 29930278
    [Abstract] [Full Text] [Related]

  • 9. Restoration of myo-inositol uptake by aldose reductase inhibitor in human skin fibroblasts cultured in high-glucose medium.
    Okuda Y, Bannai C, Nagahama M, Isaka M, Yamashita K.
    Horm Metab Res; 1991 Jan 11; 23(1):42-3. PubMed ID: 1901824
    [No Abstract] [Full Text] [Related]

  • 10. Neurotrophin-3-induced production of nerve growth factor is suppressed in Schwann cells exposed to high glucose: involvement of the polyol pathway.
    Suzuki T, Sekido H, Kato N, Nakayama Y, Yabe-Nishimura C.
    J Neurochem; 2004 Dec 11; 91(6):1430-8. PubMed ID: 15584919
    [Abstract] [Full Text] [Related]

  • 11. High glucose stimulates hyaluronan production by renal interstitial fibroblasts through the protein kinase C and transforming growth factor-beta cascade.
    Takeda M, Babazono T, Nitta K, Iwamoto Y.
    Metabolism; 2001 Jul 11; 50(7):789-94. PubMed ID: 11436183
    [Abstract] [Full Text] [Related]

  • 12. An aldose reductase inhibitor prevents glucose-induced increase in transforming growth factor-beta and protein kinase C activity in cultured mesangial cells.
    Ishii H, Tada H, Isogai S.
    Diabetologia; 1998 Mar 11; 41(3):362-4. PubMed ID: 9541179
    [Abstract] [Full Text] [Related]

  • 13. Aldose reductase inhibitor improves insulin-mediated glucose uptake and prevents migration of human coronary artery smooth muscle cells induced by high glucose.
    Yasunari K, Kohno M, Kano H, Minami M, Yoshikawa J.
    Hypertension; 2000 May 11; 35(5):1092-8. PubMed ID: 10818070
    [Abstract] [Full Text] [Related]

  • 14. Polyol pathway hyperactivity is closely related to carnitine deficiency in the pathogenesis of diabetic neuropathy of streptozotocin-diabetic rats.
    Nakamura J, Koh N, Sakakibara F, Hamada Y, Hara T, Sasaki H, Chaya S, Komori T, Nakashima E, Naruse K, Kato K, Takeuchi N, Kasuya Y, Hotta N.
    J Pharmacol Exp Ther; 1998 Dec 11; 287(3):897-902. PubMed ID: 9864270
    [Abstract] [Full Text] [Related]

  • 15. The role of polyol pathway in high glucose-induced endothelial cell damages.
    Oyama T, Miyasita Y, Watanabe H, Shirai K.
    Diabetes Res Clin Pract; 2006 Sep 11; 73(3):227-34. PubMed ID: 16624439
    [Abstract] [Full Text] [Related]

  • 16. N-Acetylcysteine and alpha-cyano-4-hydroxycinnamic acid alter protein kinase C (PKC)-delta and PKC-zeta and diminish dysmorphogenesis in rat embryos cultured with high glucose in vitro.
    Gäreskog M, Wentzel P.
    J Endocrinol; 2007 Jan 11; 192(1):207-14. PubMed ID: 17210758
    [Abstract] [Full Text] [Related]

  • 17. Epalrestat, an Aldose Reductase Inhibitor Prevents Glucose-Induced Toxicity in Human Retinal Pigment Epithelial Cells In Vitro.
    Senthilkumari S, Sharmila R, Chidambaranathan G, Vanniarajan A.
    J Ocul Pharmacol Ther; 2017 Jan 11; 33(1):34-41. PubMed ID: 27835059
    [Abstract] [Full Text] [Related]

  • 18. Polyol pathway in tissues of spontaneously diabetic Chinese hamsters (Cricetulus griseus) and the effect of an aldose reductase inhibitor, ONO-2235.
    Sekiguchi M, Watanabe K, Eto M, Iwashima Y, Morikawa A, Takahashi M, Ishii K, Makino I.
    Comp Biochem Physiol B; 1991 Jan 11; 98(4):637-40. PubMed ID: 1907900
    [Abstract] [Full Text] [Related]

  • 19. [Perspective for the treatment of diabetic neuropathy: translation from molecular studies to bedside].
    Yagihashi S, Yamagishi S, Wada R.
    Rinsho Shinkeigaku; 2005 Nov 11; 45(11):966-8. PubMed ID: 16447775
    [Abstract] [Full Text] [Related]

  • 20. Glucose dependence of glycolysis, hexose monophosphate shunt activity, energy status, and the polyol pathway in retinas isolated from normal (nondiabetic) rats.
    Winkler BS, Arnold MJ, Brassell MA, Sliter DR.
    Invest Ophthalmol Vis Sci; 1997 Jan 11; 38(1):62-71. PubMed ID: 9008631
    [Abstract] [Full Text] [Related]

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