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302 related items for PubMed ID: 12680257

  • 1. Chemopreventive efficacy of suberoylanilide hydroxamic acid (SAHA) against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis in female A/J mice.
    Desai D, Das A, Cohen L, el-Bayoumy K, Amin S.
    Anticancer Res; 2003; 23(1A):499-503. PubMed ID: 12680257
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone pulmonary metabolism and tumorigenicity in mice by analogues of the investigational chemotherapeutic drug 4-ipomeanol.
    Lin JM, Desai DH, Morse MA, Amin S, Hecht SS.
    Chem Res Toxicol; 1992; 5(5):674-9. PubMed ID: 1446008
    [Abstract] [Full Text] [Related]

  • 3. Complete inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced rat lung tumorigenesis and favorable modification of biomarkers by phenethyl isothiocyanate.
    Hecht SS, Trushin N, Rigotty J, Carmella SG, Borukhova A, Akerkar S, Rivenson A.
    Cancer Epidemiol Biomarkers Prev; 1996 Aug; 5(8):645-52. PubMed ID: 8824368
    [Abstract] [Full Text] [Related]

  • 4. Tumorigenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol enantiomers and metabolites in the A/J mouse.
    Upadhyaya P, Kenney PM, Hochalter JB, Wang M, Hecht SS.
    Carcinogenesis; 1999 Aug; 20(8):1577-82. PubMed ID: 10426810
    [Abstract] [Full Text] [Related]

  • 5. Inhibitory effects of diallyl sulfide on the metabolism and tumorigenicity of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A/J mouse lung.
    Hong JY, Wang ZY, Smith TJ, Zhou S, Shi S, Pan J, Yang CS.
    Carcinogenesis; 1992 May; 13(5):901-4. PubMed ID: 1587006
    [Abstract] [Full Text] [Related]

  • 6. Lung tumorigenicity of NNK given orally to A/J mice: its application to chemopreventive efficacy studies.
    Castonguay A, Pepin P, Stoner GD.
    Exp Lung Res; 1991 May; 17(2):485-99. PubMed ID: 2050045
    [Abstract] [Full Text] [Related]

  • 7. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human lung and liver microsomes and cytochromes P-450 expressed in hepatoma cells.
    Smith TJ, Guo Z, Gonzalez FJ, Guengerich FP, Stoner GD, Yang CS.
    Cancer Res; 1992 Apr 01; 52(7):1757-63. PubMed ID: 1312898
    [Abstract] [Full Text] [Related]

  • 8. Effects of indole-3-carbinol on lung tumorigenesis and DNA methylation induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and on the metabolism and disposition of NNK in A/J mice.
    Morse MA, LaGreca SD, Amin SG, Chung FL.
    Cancer Res; 1990 May 01; 50(9):2613-7. PubMed ID: 2328487
    [Abstract] [Full Text] [Related]

  • 9. Prevention of NNK-induced lung tumorigenesis in A/J mice by acetylsalicylic acid and NS-398.
    Rioux N, Castonguay A.
    Cancer Res; 1998 Dec 01; 58(23):5354-60. PubMed ID: 9850065
    [Abstract] [Full Text] [Related]

  • 10. Mechanisms of inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation in mouse by dietary phenethyl isothiocyanate.
    Smith TJ, Guo Z, Li C, Ning SM, Thomas PE, Yang CS.
    Cancer Res; 1993 Jul 15; 53(14):3276-82. PubMed ID: 8324738
    [Abstract] [Full Text] [Related]

  • 11. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes and its inhibition by isothiocyanates.
    Smith TJ, Guo ZY, Thomas PE, Chung FL, Morse MA, Elkind K, Yang CS.
    Cancer Res; 1990 Nov 01; 50(21):6817-22. PubMed ID: 2208146
    [Abstract] [Full Text] [Related]

  • 12. Mechanisms of chemopreventive effects of 8-methoxypsoralen against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung adenomas.
    Miyazaki M, Yamazaki H, Takeuchi H, Saoo K, Yokohira M, Masumura K, Nohmi T, Funae Y, Imaida K, Kamataki T.
    Carcinogenesis; 2005 Nov 01; 26(11):1947-55. PubMed ID: 15958517
    [Abstract] [Full Text] [Related]

  • 13. Effect of tobacco smoke condensate on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by adult and fetal hamster microsomes.
    Jorquera R, Castonguay A, Schuller HM.
    Drug Metab Dispos; 1993 Nov 01; 21(2):318-24. PubMed ID: 8097703
    [Abstract] [Full Text] [Related]

  • 14. A/J mouse lung tumorigenesis by the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its inhibition by arylalkyl isothiocyanates.
    Hecht SS, Morse MA, Eklind KI, Chung FL.
    Exp Lung Res; 1991 Nov 01; 17(2):501-11. PubMed ID: 2050046
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by dietary benzaldehydes.
    Morse MA, Kresty LA, Toburen AL.
    Cancer Lett; 1995 Nov 06; 97(2):255-61. PubMed ID: 7497471
    [Abstract] [Full Text] [Related]

  • 16. Comparison of the chemopreventive efficacies of 1,4-phenylenebis(methylene)selenocyanate and selenium-enriched yeast on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced lung tumorigenesis in A/J mouse.
    Das A, Desai D, Pittman B, Amin S, El-Bayoumy K.
    Nutr Cancer; 2003 Nov 06; 46(2):179-85. PubMed ID: 14690794
    [Abstract] [Full Text] [Related]

  • 17. Effects of dietary 1,4-phenylenebis(methylene)selenocyanate on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation in lung and liver of A/J mice and F344 rats.
    Prokopczyk B, Cox JE, Upadhyaya P, Amin S, Desai D, Hoffmann D, el-Bayoumy K.
    Carcinogenesis; 1996 Apr 06; 17(4):749-53. PubMed ID: 8625486
    [Abstract] [Full Text] [Related]

  • 18. Enzymes involved in the bioactivation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in patas monkey lung and liver microsomes.
    Smith TJ, Liao AM, Liu Y, Jones AB, Anderson LM, Yang CS.
    Carcinogenesis; 1997 Aug 06; 18(8):1577-84. PubMed ID: 9276633
    [Abstract] [Full Text] [Related]

  • 19. Stereospecific deuterium substitution attenuates the tumorigenicity and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Jalas JR, McIntee EJ, Kenney PM, Upadhyaya P, Peterson LA, Hecht SS.
    Chem Res Toxicol; 2003 Jun 06; 16(6):794-806. PubMed ID: 12807363
    [Abstract] [Full Text] [Related]

  • 20. Pretreatment with 8-methoxypsoralen, a potent human CYP2A6 inhibitor, strongly inhibits lung tumorigenesis induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in female A/J mice.
    Takeuchi H, Saoo K, Yokohira M, Ikeda M, Maeta H, Miyazaki M, Yamazaki H, Kamataki T, Imaida K.
    Cancer Res; 2003 Nov 15; 63(22):7581-3. PubMed ID: 14633670
    [Abstract] [Full Text] [Related]


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