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168 related items for PubMed ID: 12680782

  • 1. Mitochondria play a central role in apoptosis induced by alpha-tocopheryl succinate, an agent with antineoplastic activity: comparison with receptor-mediated pro-apoptotic signaling.
    Weber T, Dalen H, Andera L, Nègre-Salvayre A, Augé N, Sticha M, Lloret A, Terman A, Witting PK, Higuchi M, Plasilova M, Zivny J, Gellert N, Weber C, Neuzil J.
    Biochemistry; 2003 Apr 15; 42(14):4277-91. PubMed ID: 12680782
    [Abstract] [Full Text] [Related]

  • 2. Vitamin E analogs trigger apoptosis in HER2/erbB2-overexpressing breast cancer cells by signaling via the mitochondrial pathway.
    Wang XF, Witting PK, Salvatore BA, Neuzil J.
    Biochem Biophys Res Commun; 2005 Jan 14; 326(2):282-9. PubMed ID: 15582575
    [Abstract] [Full Text] [Related]

  • 3. Alpha-tocopheryl succinate selectively induces apoptosis in neuroblastoma cells: potential therapy of malignancies of the nervous system?
    Swettenham E, Witting PK, Salvatore BA, Neuzil J.
    J Neurochem; 2005 Sep 14; 94(5):1448-56. PubMed ID: 16001965
    [Abstract] [Full Text] [Related]

  • 4. Tocopherol-associated protein-1 accelerates apoptosis induced by alpha-tocopheryl succinate in mesothelioma cells.
    Neuzil J, Dong LF, Wang XF, Zingg JM.
    Biochem Biophys Res Commun; 2006 May 19; 343(4):1113-7. PubMed ID: 16579965
    [Abstract] [Full Text] [Related]

  • 5. RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells involves Bax translocation to mitochondria.
    Yu W, Sanders BG, Kline K.
    Cancer Res; 2003 May 15; 63(10):2483-91. PubMed ID: 12750270
    [Abstract] [Full Text] [Related]

  • 6. Vitamin E succinate is a potent novel antineoplastic agent with high selectivity and cooperativity with tumor necrosis factor-related apoptosis-inducing ligand (Apo2 ligand) in vivo.
    Weber T, Lu M, Andera L, Lahm H, Gellert N, Fariss MW, Korinek V, Sattler W, Ucker DS, Terman A, Schröder A, Erl W, Brunk UT, Coffey RJ, Weber C, Neuzil J.
    Clin Cancer Res; 2002 Mar 15; 8(3):863-9. PubMed ID: 11895920
    [Abstract] [Full Text] [Related]

  • 7. Alpha-tocopheryl succinate sensitizes human colon cancer cells to exisulind-induced apoptosis.
    Lim SJ, Lee YJ, Park DH, Lee E, Choi MK, Park W, Chun KH, Choi HG, Cho JS.
    Apoptosis; 2007 Feb 15; 12(2):423-31. PubMed ID: 17191116
    [Abstract] [Full Text] [Related]

  • 8. Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.
    Wu SJ, Ng LT, Lin CC.
    Eur J Pharmacol; 2005 Aug 22; 518(2-3):96-106. PubMed ID: 16054126
    [Abstract] [Full Text] [Related]

  • 9. Bid integrates intrinsic and extrinsic signaling in apoptosis induced by alpha-tocopheryl succinate in human gastric carcinoma cells.
    Zhao Y, Li R, Xia W, Neuzil J, Lu Y, Zhang H, Zhao X, Zhang X, Sun C, Wu K.
    Cancer Lett; 2010 Feb 01; 288(1):42-9. PubMed ID: 19640637
    [Abstract] [Full Text] [Related]

  • 10. Intracellular mechanisms mediating tocotrienol-induced apoptosis in neoplastic mammary epithelial cells.
    Sylvester PW, Shah S.
    Asia Pac J Clin Nutr; 2005 Feb 01; 14(4):366-73. PubMed ID: 16326643
    [Abstract] [Full Text] [Related]

  • 11. alpha-TEA inhibits survival and enhances death pathways in cisplatin sensitive and resistant human ovarian cancer cells.
    Yu W, Shun MC, Anderson K, Chen H, Sanders BG, Kline K.
    Apoptosis; 2006 Oct 01; 11(10):1813-23. PubMed ID: 16850165
    [Abstract] [Full Text] [Related]

  • 12. Role of death receptor and mitochondrial pathways in conventional chemotherapy drug induction of apoptosis.
    Wang P, Song JH, Song DK, Zhang J, Hao C.
    Cell Signal; 2006 Sep 01; 18(9):1528-35. PubMed ID: 16442262
    [Abstract] [Full Text] [Related]

  • 13. X-linked inhibitor regulating TRAIL-induced apoptosis in chemoresistant human primary glioblastoma cells.
    Roa WH, Chen H, Fulton D, Gulavita S, Shaw A, Th'ng J, Farr-Jones M, Moore R, Petruk K.
    Clin Invest Med; 2003 Oct 01; 26(5):231-42. PubMed ID: 14596484
    [Abstract] [Full Text] [Related]

  • 14. Role of caspases in Ox-LDL-induced apoptotic cascade in human coronary artery endothelial cells.
    Chen J, Mehta JL, Haider N, Zhang X, Narula J, Li D.
    Circ Res; 2004 Feb 20; 94(3):370-6. PubMed ID: 14684629
    [Abstract] [Full Text] [Related]

  • 15. alpha-Tocopheryl succinate-induced apoptosis in human gastric cancer cells is modulated by ERK1/2 and c-Jun N-terminal kinase in a biphasic manner.
    Zhao Y, Zhao X, Yang B, Neuzil J, Wu K.
    Cancer Lett; 2007 Mar 18; 247(2):345-52. PubMed ID: 16839662
    [Abstract] [Full Text] [Related]

  • 16. Alpha-tocopheryl succinate induces DR4 and DR5 expression by a p53-dependent route: implication for sensitisation of resistant cancer cells to TRAIL apoptosis.
    Tomasetti M, Andera L, Alleva R, Borghi B, Neuzil J, Procopio A.
    FEBS Lett; 2006 Apr 03; 580(8):1925-31. PubMed ID: 16529749
    [Abstract] [Full Text] [Related]

  • 17. Cephalostatin 1 selectively triggers the release of Smac/DIABLO and subsequent apoptosis that is characterized by an increased density of the mitochondrial matrix.
    Dirsch VM, Müller IM, Eichhorst ST, Pettit GR, Kamano Y, Inoue M, Xu JP, Ichihara Y, Wanner G, Vollmar AM.
    Cancer Res; 2003 Dec 15; 63(24):8869-76. PubMed ID: 14695204
    [Abstract] [Full Text] [Related]

  • 18. Imatinib enhances human melanoma cell susceptibility to TRAIL-induced cell death: Relationship to Bcl-2 family and caspase activation.
    Hamaï A, Richon C, Meslin F, Faure F, Kauffmann A, Lecluse Y, Jalil A, Larue L, Avril MF, Chouaib S, Mehrpour M.
    Oncogene; 2006 Dec 07; 25(58):7618-34. PubMed ID: 16983347
    [Abstract] [Full Text] [Related]

  • 19. Induction of cancer cell apoptosis by alpha-tocopheryl succinate: molecular pathways and structural requirements.
    Neuzil J, Weber T, Schröder A, Lu M, Ostermann G, Gellert N, Mayne GC, Olejnicka B, Nègre-Salvayre A, Stícha M, Coffey RJ, Weber C.
    FASEB J; 2001 Feb 07; 15(2):403-15. PubMed ID: 11156956
    [Abstract] [Full Text] [Related]

  • 20. Critical roles for JNK, c-Jun, and Fas/FasL-Signaling in vitamin E analog-induced apoptosis in human prostate cancer cells.
    Jia L, Yu W, Wang P, Li J, Sanders BG, Kline K.
    Prostate; 2008 Mar 01; 68(4):427-41. PubMed ID: 18196534
    [Abstract] [Full Text] [Related]

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