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1198 related items for PubMed ID: 12684430

  • 1. Rapid and selective apoptosis in human leukemic cells induced by Aplidine through a Fas/CD95- and mitochondrial-mediated mechanism.
    Gajate C, An F, Mollinedo F.
    Clin Cancer Res; 2003 Apr; 9(4):1535-45. PubMed ID: 12684430
    [Abstract] [Full Text] [Related]

  • 2. Involvement of mitochondria and recruitment of Fas/CD95 signaling in lipid rafts in resveratrol-mediated antimyeloma and antileukemia actions.
    Reis-Sobreiro M, Gajate C, Mollinedo F.
    Oncogene; 2009 Sep 10; 28(36):3221-34. PubMed ID: 19561642
    [Abstract] [Full Text] [Related]

  • 3. Sustained activation of p38 mitogen-activated protein kinase and c-Jun N-terminal kinase pathways by hepatitis B virus X protein mediates apoptosis via induction of Fas/FasL and tumor necrosis factor (TNF) receptor 1/TNF-alpha expression.
    Wang WH, Grégori G, Hullinger RL, Andrisani OM.
    Mol Cell Biol; 2004 Dec 10; 24(23):10352-65. PubMed ID: 15542843
    [Abstract] [Full Text] [Related]

  • 4. The recruitment of Fas-associated death domain/caspase-8 in Ras-induced apoptosis.
    Chen CY, Juo P, Liou JS, Li CQ, Yu Q, Blenis J, Faller DV.
    Cell Growth Differ; 2001 Jun 10; 12(6):297-306. PubMed ID: 11432804
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of JNK signaling diminishes early but not late cellular stress-induced apoptosis.
    Krilleke D, Ucur E, Pulte D, Schulze-Osthoff K, Debatin KM, Herr I.
    Int J Cancer; 2003 Nov 20; 107(4):520-7. PubMed ID: 14520687
    [Abstract] [Full Text] [Related]

  • 6. Tumor-induced apoptosis of T cells: amplification by a mitochondrial cascade.
    Gastman BR, Yin XM, Johnson DE, Wieckowski E, Wang GQ, Watkins SC, Rabinowich H.
    Cancer Res; 2000 Dec 15; 60(24):6811-7. PubMed ID: 11156370
    [Abstract] [Full Text] [Related]

  • 7. Induction and regulation of Fas-mediated apoptosis in human thyroid epithelial cells.
    Mezosi E, Wang SH, Utsugi S, Bajnok L, Bretz JD, Gauger PG, Thompson NW, Baker JR.
    Mol Endocrinol; 2005 Mar 15; 19(3):804-11. PubMed ID: 15563545
    [Abstract] [Full Text] [Related]

  • 8. Apoptosis signaling triggered by the marine alkaloid ascididemin is routed via caspase-2 and JNK to mitochondria.
    Dirsch VM, Kirschke SO, Estermeier M, Steffan B, Vollmar AM.
    Oncogene; 2004 Feb 26; 23(8):1586-93. PubMed ID: 14716300
    [Abstract] [Full Text] [Related]

  • 9. Protein synthesis-dependent apoptotic signalling pathway in X-irradiated MOLT-4 human leukaemia cell line.
    Takahashi K, Inanami O, Hayashi M, Kuwabara M.
    Int J Radiat Biol; 2002 Feb 26; 78(2):115-24. PubMed ID: 11779361
    [Abstract] [Full Text] [Related]

  • 10. Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis.
    Fulda S, Meyer E, Friesen C, Susin SA, Kroemer G, Debatin KM.
    Oncogene; 2001 Mar 01; 20(9):1063-75. PubMed ID: 11314043
    [Abstract] [Full Text] [Related]

  • 11. MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly.
    Holmström TH, Schmitz I, Söderström TS, Poukkula M, Johnson VL, Chow SC, Krammer PH, Eriksson JE.
    EMBO J; 2000 Oct 16; 19(20):5418-28. PubMed ID: 11032809
    [Abstract] [Full Text] [Related]

  • 12. Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8.
    Söderström TS, Poukkula M, Holmström TH, Heiskanen KM, Eriksson JE.
    J Immunol; 2002 Sep 15; 169(6):2851-60. PubMed ID: 12218097
    [Abstract] [Full Text] [Related]

  • 13. Daxx deletion mutant (amino acids 501-625)-induced apoptosis occurs through the JNK/p38-Bax-dependent mitochondrial pathway.
    Song JJ, Lee YJ.
    J Cell Biochem; 2004 Aug 15; 92(6):1257-70. PubMed ID: 15258908
    [Abstract] [Full Text] [Related]

  • 14. Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of Bcl-2 and Bcl-xl.
    Anto RJ, Mukhopadhyay A, Denning K, Aggarwal BB.
    Carcinogenesis; 2002 Jan 15; 23(1):143-50. PubMed ID: 11756235
    [Abstract] [Full Text] [Related]

  • 15. Induction of apoptosis by apicidin, a histone deacetylase inhibitor, via the activation of mitochondria-dependent caspase cascades in human Bcr-Abl-positive leukemia cells.
    Cheong JW, Chong SY, Kim JY, Eom JI, Jeung HK, Maeng HY, Lee ST, Min YH.
    Clin Cancer Res; 2003 Oct 15; 9(13):5018-27. PubMed ID: 14581377
    [Abstract] [Full Text] [Related]

  • 16. Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.
    Wu SJ, Ng LT, Lin CC.
    Eur J Pharmacol; 2005 Aug 22; 518(2-3):96-106. PubMed ID: 16054126
    [Abstract] [Full Text] [Related]

  • 17. Metabolic inhibitors sensitize for CD95 (APO-1/Fas)-induced apoptosis by down-regulating Fas-associated death domain-like interleukin 1-converting enzyme inhibitory protein expression.
    Fulda S, Meyer E, Debatin KM.
    Cancer Res; 2000 Jul 15; 60(14):3947-56. PubMed ID: 10919673
    [Abstract] [Full Text] [Related]

  • 18. Heat stress downregulates FLIP and sensitizes cells to Fas receptor-mediated apoptosis.
    Tran SE, Meinander A, Holmström TH, Rivero-Müller A, Heiskanen KM, Linnau EK, Courtney MJ, Mosser DD, Sistonen L, Eriksson JE.
    Cell Death Differ; 2003 Oct 15; 10(10):1137-47. PubMed ID: 14502237
    [Abstract] [Full Text] [Related]

  • 19. JNK (c-Jun N-terminal kinase) and p38 activation in receptor-mediated and chemically-induced apoptosis of T-cells: differential requirements for caspase activation.
    MacFarlane M, Cohen GM, Dickens M.
    Biochem J; 2000 May 15; 348 Pt 1(Pt 1):93-101. PubMed ID: 10794718
    [Abstract] [Full Text] [Related]

  • 20. Activation of extracellular signal-regulated kinase and c-Jun-NH(2)-terminal kinase but not p38 mitogen-activated protein kinases is required for RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells.
    Yu W, Liao QY, Hantash FM, Sanders BG, Kline K.
    Cancer Res; 2001 Sep 01; 61(17):6569-76. PubMed ID: 11522656
    [Abstract] [Full Text] [Related]

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