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147 related items for PubMed ID: 12690118

  • 1. Identification of cytoplasmic domains of hVPAC1 receptor required for activation of adenylyl cyclase. Crucial role of two charged amino acids strictly conserved in class II G protein-coupled receptors.
    Couvineau A, Lacapere JJ, Tan YV, Rouyer-Fessard C, Nicole P, Laburthe M.
    J Biol Chem; 2003 Jul 04; 278(27):24759-66. PubMed ID: 12690118
    [Abstract] [Full Text] [Related]

  • 2. Serine 447 in the carboxyl tail of human VPAC1 receptor is crucial for agonist-induced desensitization but not internalization of the receptor.
    Marie JC, Rouyer-Fessard C, Couvineau A, Nicole P, Devaud H, El Benna J, Laburthe M.
    Mol Pharmacol; 2003 Dec 04; 64(6):1565-74. PubMed ID: 14645688
    [Abstract] [Full Text] [Related]

  • 3. Diffuse pharmacophoric domains of vasoactive intestinal peptide (VIP) and further insights into the interaction of VIP with the N-terminal ectodomain of human VPAC1 receptor by photoaffinity labeling with [Bpa6]-VIP.
    Tan YV, Couvineau A, Laburthe M.
    J Biol Chem; 2004 Sep 10; 279(37):38889-94. PubMed ID: 15247290
    [Abstract] [Full Text] [Related]

  • 4. Photoaffinity labeling demonstrates physical contact between vasoactive intestinal peptide and the N-terminal ectodomain of the human VPAC1 receptor.
    Tan YV, Couvineau A, Van Rampelbergh J, Laburthe M.
    J Biol Chem; 2003 Sep 19; 278(38):36531-6. PubMed ID: 12807902
    [Abstract] [Full Text] [Related]

  • 5. The human VPAC1 receptor: three-dimensional model and mutagenesis of the N-terminal domain.
    Lins L, Couvineau A, Rouyer-Fessard C, Nicole P, Maoret JJ, Benhamed M, Brasseur R, Thomas A, Laburthe M.
    J Biol Chem; 2001 Mar 30; 276(13):10153-60. PubMed ID: 11124960
    [Abstract] [Full Text] [Related]

  • 6. Presence of a N-terminal signal peptide in class II G protein-coupled receptors: crucial role for expression of the human VPAC1 receptor.
    Couvineau A, Rouyer-Fessard C, Laburthe M.
    Regul Pept; 2004 Dec 15; 123(1-3):181-5. PubMed ID: 15518910
    [Abstract] [Full Text] [Related]

  • 7. Effect of inactivating mutations on phosphorylation and internalization of the human VPAC2 receptor.
    Langer I, Langlet C, Robberecht P.
    J Mol Endocrinol; 2005 Apr 15; 34(2):405-14. PubMed ID: 15821106
    [Abstract] [Full Text] [Related]

  • 8. Identification of a VIP-specific receptor in guinea pig tenia coli.
    Teng BQ, Grider JR, Murthy KS.
    Am J Physiol Gastrointest Liver Physiol; 2001 Sep 15; 281(3):G718-25. PubMed ID: 11518684
    [Abstract] [Full Text] [Related]

  • 9. Properties of the pituitary adenylate cyclase-activating polypeptide I and II receptors, vasoactive intestinal peptide1, and chimeric amino-terminal pituitary adenylate cyclase-activating polypeptide/vasoactive intestinal peptide1 receptors: evidence for multiple receptor states.
    Van Rampelbergh J, Gourlet P, De Neef P, Robberecht P, Waelbroeck M.
    Mol Pharmacol; 1996 Dec 15; 50(6):1596-604. PubMed ID: 8967982
    [Abstract] [Full Text] [Related]

  • 10. The human vasoactive intestinal Peptide/Pituitary adenylate cyclase activating peptide receptor 1 (VPAC1): constitutive activation by mutations at threonine 343.
    Gaudin P, Couvineau A, Rouyer-Fessard C, Maoret JJ, Laburthe M.
    Biochem Biophys Res Commun; 1999 Jan 08; 254(1):15-20. PubMed ID: 9920725
    [Abstract] [Full Text] [Related]

  • 11. Identification of key residues for interaction of vasoactive intestinal peptide with human VPAC1 and VPAC2 receptors and development of a highly selective VPAC1 receptor agonist. Alanine scanning and molecular modeling of the peptide.
    Nicole P, Lins L, Rouyer-Fessard C, Drouot C, Fulcrand P, Thomas A, Couvineau A, Martinez J, Brasseur R, Laburthe M.
    J Biol Chem; 2000 Aug 04; 275(31):24003-12. PubMed ID: 10801840
    [Abstract] [Full Text] [Related]

  • 12. Role of charged amino acids conserved in the vasoactive intestinal polypeptide/secretin family of receptors on the secretin receptor functionality.
    Di Paolo E, Vilardaga JP, Petry H, Moguilevsky N, Bollen A, Robberecht P, Waelbroeck M.
    Peptides; 1999 Aug 04; 20(10):1187-93. PubMed ID: 10573290
    [Abstract] [Full Text] [Related]

  • 13. A cloned frog vasoactive intestinal polypeptide/pituitary adenylate cyclase-activating polypeptide receptor exhibits pharmacological and tissue distribution characteristics of both VPAC1 and VPAC2 receptors in mammals.
    Alexandre D, Anouar Y, Jegou S, Fournier A, Vaudry H.
    Endocrinology; 1999 Mar 04; 140(3):1285-93. PubMed ID: 10067855
    [Abstract] [Full Text] [Related]

  • 14. Proline residue 280 in the second extracellular loop (EC2) of the VPAC2 receptor is essential for the receptor structure.
    Vertongen P, Solano RM, Juarranz MG, Perret J, Waelbroeck M, Robberecht P.
    Peptides; 2001 Sep 04; 22(9):1363-70. PubMed ID: 11514016
    [Abstract] [Full Text] [Related]

  • 15. Contribution of the carboxyl terminus of the VPAC1 receptor to agonist-induced receptor phosphorylation, internalization, and recycling.
    Langlet C, Langer I, Vertongen P, Gaspard N, Vanderwinden JM, Robberecht P.
    J Biol Chem; 2005 Jul 29; 280(30):28034-43. PubMed ID: 15932876
    [Abstract] [Full Text] [Related]

  • 16. Peptide agonist docking in the N-terminal ectodomain of a class II G protein-coupled receptor, the VPAC1 receptor. Photoaffinity, NMR, and molecular modeling.
    Tan YV, Couvineau A, Murail S, Ceraudo E, Neumann JM, Lacapère JJ, Laburthe M.
    J Biol Chem; 2006 May 05; 281(18):12792-8. PubMed ID: 16520374
    [Abstract] [Full Text] [Related]

  • 17. Properties of chimeric secretin and VIP receptor proteins indicate the importance of the N-terminal domain for ligand discrimination.
    Vilardaga JP, De Neef P, Di Paolo E, Bollen A, Waelbroeck M, Robberecht P.
    Biochem Biophys Res Commun; 1995 Jun 26; 211(3):885-91. PubMed ID: 7598719
    [Abstract] [Full Text] [Related]

  • 18. Lysine 195 and aspartate 196 in the first extracellular loop of the VPAC1 receptor are essential for high affinity binding of agonists but not of antagonists.
    Langer I, Vertongen P, Perret J, Waelbroeck M, Robberecht P.
    Neuropharmacology; 2003 Jan 26; 44(1):125-31. PubMed ID: 12559130
    [Abstract] [Full Text] [Related]

  • 19. Mutations in the carboxy-terminus of the third intracellular loop of the human recombinant VPAC1 receptor impair VIP-stimulated [Ca2+]i increase but not adenylate cyclase stimulation.
    Langer I, Robberecht P.
    Cell Signal; 2005 Jan 26; 17(1):17-24. PubMed ID: 15451021
    [Abstract] [Full Text] [Related]

  • 20. The long-acting vasoactive intestinal polypeptide agonist RO 25-1553 is highly selective of the VIP2 receptor subclass.
    Gourlet P, Vertongen P, Vandermeers A, Vandermeers-Piret MC, Rathe J, De Neef P, Waelbroeck M, Robberecht P.
    Peptides; 1997 Jan 26; 18(3):403-8. PubMed ID: 9145428
    [Abstract] [Full Text] [Related]

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