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Journal Abstract Search

533 related items for PubMed ID: 12693024

  • 1. The pyridyloxobutyl DNA adduct, O6-[4-oxo-4-(3-pyridyl)butyl]guanine, is detected in tissues from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-treated A/J mice.
    Thomson NM, Kenney PM, Peterson LA.
    Chem Res Toxicol; 2003 Jan; 16(1):1-6. PubMed ID: 12693024
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  • 2. Pyridyloxobutyl adduct O6-[4-oxo-4-(3-pyridyl)butyl]guanine is present in 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone-treated DNA and is a substrate for O6-alkylguanine-DNA alkyltransferase.
    Wang L, Spratt TE, Liu XK, Hecht SS, Pegg AE, Peterson LA.
    Chem Res Toxicol; 1997 May; 10(5):562-7. PubMed ID: 9168254
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  • 3. The repair of the tobacco specific nitrosamine derived adduct O6-[4-Oxo-4-(3-pyridyl)butyl]guanine by O6-alkylguanine-DNA alkyltransferase variants.
    Mijal RS, Thomson NM, Fleischer NL, Pauly GT, Moschel RC, Kanugula S, Fang Q, Pegg AE, Peterson LA.
    Chem Res Toxicol; 2004 Mar; 17(3):424-34. PubMed ID: 15025514
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  • 5. Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Upadhyaya P, Kalscheuer S, Hochalter JB, Villalta PW, Hecht SS.
    Chem Res Toxicol; 2008 Jul; 21(7):1468-76. PubMed ID: 18570389
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  • 7. Development of a quantitative liquid chromatography/electrospray mass spectrometric assay for a mutagenic tobacco specific nitrosamine-derived DNA adduct, O6-[4-Oxo-4-(3-pyridyl)butyl]-2'-deoxyguanosine.
    Thomson NM, Mijal RS, Ziegel R, Fleischer NL, Pegg AE, Tretyakova NY, Peterson LA.
    Chem Res Toxicol; 2004 Dec; 17(12):1600-6. PubMed ID: 15606135
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  • 9. O6-methylguanine is a critical determinant of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone tumorigenesis in A/J mouse lung.
    Peterson LA, Hecht SS.
    Cancer Res; 1991 Oct 15; 51(20):5557-64. PubMed ID: 1913675
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  • 11. Synthesis of DNA oligonucleotides containing site-specifically incorporated O6-[4-oxo-4-(3-pyridyl)butyl]guanine and their reaction with O6-alkylguanine-DNA alkyltransferase.
    Wang L, Spratt TE, Pegg AE, Peterson LA.
    Chem Res Toxicol; 1999 Feb 15; 12(2):127-31. PubMed ID: 10027788
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  • 12. Quantitation of pyridyloxobutyl DNA adducts of tobacco-specific nitrosamines in rat tissue DNA by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry.
    Lao Y, Villalta PW, Sturla SJ, Wang M, Hecht SS.
    Chem Res Toxicol; 2006 May 15; 19(5):674-82. PubMed ID: 16696570
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  • 13. Pyridyloxobutylation of guanine residues by 4-[(acetoxymethyl)nitrosamino]-1-(3-pyridyl)-1-butanone generates substrates of O6-alkylguanine-DNA alkyltransferase.
    Liu XK, Spratt TE, Murphy SE, Peterson LA.
    Chem Res Toxicol; 1996 Sep 15; 9(6):949-53. PubMed ID: 8870981
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  • 16. Effects of deuterium substitution on the tumorigenicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in A/J mice.
    Hecht SS, Jordan KG, Choi CI, Trushin N.
    Carcinogenesis; 1990 Jun 15; 11(6):1017-20. PubMed ID: 2347060
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  • 17. Analysis of pyridyloxobutyl and pyridylhydroxybutyl DNA adducts in extrahepatic tissues of F344 rats treated chronically with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Zhang S, Wang M, Villalta PW, Lindgren BR, Upadhyaya P, Lao Y, Hecht SS.
    Chem Res Toxicol; 2009 May 15; 22(5):926-36. PubMed ID: 19358518
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  • 18. Immunocytochemical identification of DNA adducts, O6-methylguanine and 7-methylguanine, in respiratory and other tissues of rat, mouse and Syrian hamster exposed to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Van Benthem J, Feron VJ, Leeman WR, Wilmer JW, Vermeulen E, den Engelse L, Scherer E.
    Carcinogenesis; 1994 Sep 15; 15(9):2023-9. PubMed ID: 7522985
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  • 19. Effects of dietary 1,4-phenylenebis(methylene)selenocyanate on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation in lung and liver of A/J mice and F344 rats.
    Prokopczyk B, Cox JE, Upadhyaya P, Amin S, Desai D, Hoffmann D, el-Bayoumy K.
    Carcinogenesis; 1996 Apr 15; 17(4):749-53. PubMed ID: 8625486
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  • 20. Analysis and Identification of 2'-Deoxyadenosine-Derived Adducts in Lung and Liver DNA of F-344 Rats Treated with the Tobacco-Specific Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Carlson ES, Upadhyaya P, Villalta PW, Ma B, Hecht SS.
    Chem Res Toxicol; 2018 May 21; 31(5):358-370. PubMed ID: 29651838
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