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374 related items for PubMed ID: 12694748

  • 1. Use of HepG2 cell line for direct or indirect mutagens screening: comparative investigation between comet and micronucleus assays.
    Valentin-Severin I, Le Hegarat L, Lhuguenot JC, Le Bon AM, Chagnon MC.
    Mutat Res; 2003 Apr 20; 536(1-2):79-90. PubMed ID: 12694748
    [Abstract] [Full Text] [Related]

  • 2. Assessment of the genotoxic potential of indirect chemical mutagens in HepaRG cells by the comet and the cytokinesis-block micronucleus assays.
    Le Hegarat L, Dumont J, Josse R, Huet S, Lanceleur R, Mourot A, Poul JM, Guguen-Guillouzo C, Guillouzo A, Fessard V.
    Mutagenesis; 2010 Nov 20; 25(6):555-60. PubMed ID: 20675360
    [Abstract] [Full Text] [Related]

  • 3. The autoradiographic test for unscheduled DNA synthesis: a sensitive assay for the detection of DNA repair in the HepG2 cell line.
    Valentin-Severin I, Thybaud V, Le Bon AM, Lhuguenot JC, Chagnon MC.
    Mutat Res; 2004 Apr 11; 559(1-2):211-7. PubMed ID: 15066588
    [Abstract] [Full Text] [Related]

  • 4. Comparative study of the comet assay and the micronucleus test in amphibian larvae (Xenopus laevis) using benzo(a)pyrene, ethyl methanesulfonate, and methyl methanesulfonate: establishment of a positive control in the amphibian comet assay.
    Mouchet F, Gauthier L, Mailhes C, Ferrier V, Devaux A.
    Environ Toxicol; 2005 Feb 11; 20(1):74-84. PubMed ID: 15712291
    [Abstract] [Full Text] [Related]

  • 5. Synergistic DNA damaging effects of 4-nitroquinoline-1-oxide and non-effective concentrations of methyl methanesulfonate in human fibroblasts.
    Hömme M, Jacobi H, Juhl-Strauss U, Witte I.
    Mutat Res; 2000 Nov 09; 461(3):211-9. PubMed ID: 11056292
    [Abstract] [Full Text] [Related]

  • 6. Detection of aneugenic and clastogenic potential of X-rays, directly and indirectly acting chemicals in human hepatoma (Hep G2) and peripheral blood lymphocytes, using the micronucleus assay and fluorescent in situ hybridization with a DNA centromeric probe.
    Darroudi F, Meijers CM, Hadjidekova V, Natarajan AT.
    Mutagenesis; 1996 Sep 09; 11(5):425-33. PubMed ID: 8921503
    [Abstract] [Full Text] [Related]

  • 7. Comparison of alkaline single cell gel (Comet) and peripheral blood micronucleus assays in detecting DNA damage caused by direct and indirect acting mutagens.
    Vrzoc M, Petras ML.
    Mutat Res; 1997 Nov 19; 381(1):31-40. PubMed ID: 9403028
    [Abstract] [Full Text] [Related]

  • 8. Comet assay in murine bone-marrow cell line (FDC-P2).
    Oshida K, Iwanaga E, Miyamoto K, Miyamoto Y.
    Toxicol In Vitro; 2010 Apr 19; 24(3):1039-44. PubMed ID: 19925857
    [Abstract] [Full Text] [Related]

  • 9. A co-culture system of human intestinal Caco-2 cells and lymphoblastoid TK6 cells for investigating the genotoxicity of oral compounds.
    Le Hégarat L, Huet S, Fessard V.
    Mutagenesis; 2012 Nov 19; 27(6):631-6. PubMed ID: 22844081
    [Abstract] [Full Text] [Related]

  • 10. Induction and repair of DNA damage measured by the comet assay in human T lymphocytes separated by immunomagnetic cell sorting.
    Bausinger J, Speit G.
    Mutat Res; 2014 Nov 19; 769():42-8. PubMed ID: 25771724
    [Abstract] [Full Text] [Related]

  • 11. Liver-on-chip model and application in predictive genotoxicity and mutagenicity of drugs.
    Kopp B, Khawam A, Di Perna K, Lenart D, Vinette M, Silva R, Zanoni TB, Rore C, Guenigault G, Richardson E, Kostrzewski T, Boswell A, Van P, Valentine Iii C, Salk J, Hamel A.
    Mutat Res Genet Toxicol Environ Mutagen; 2024 Nov 19; 896():503762. PubMed ID: 38821675
    [Abstract] [Full Text] [Related]

  • 12. Evaluation of a multi-endpoint assay in rats, combining the bone-marrow micronucleus test, the Comet assay and the flow-cytometric peripheral blood micronucleus test.
    Bowen DE, Whitwell JH, Lillford L, Henderson D, Kidd D, Mc Garry S, Pearce G, Beevers C, Kirkland DJ, Work conducted at Covance Laboratories Ltd., Harrogate.
    Mutat Res; 2011 May 18; 722(1):7-19. PubMed ID: 21356328
    [Abstract] [Full Text] [Related]

  • 13. A combination of in vitro comet assay and micronucleus test using human lymphoblastoid TK6 cells.
    Kimura A, Miyata A, Honma M.
    Mutagenesis; 2013 Sep 18; 28(5):583-90. PubMed ID: 23863314
    [Abstract] [Full Text] [Related]

  • 14. Evaluation of the protective effect of ascorbic acid on nitrite- and nitrosamine-induced cytotoxicity and genotoxicity in human hepatoma line.
    Erkekoglu P, Baydar T.
    Toxicol Mech Methods; 2010 Feb 18; 20(2):45-52. PubMed ID: 20100056
    [Abstract] [Full Text] [Related]

  • 15. Genotoxic evaluation of the non-halogenated disinfection by-products nitrosodimethylamine and nitrosodiethylamine.
    Liviac D, Creus A, Marcos R.
    J Hazard Mater; 2011 Jan 30; 185(2-3):613-8. PubMed ID: 20952128
    [Abstract] [Full Text] [Related]

  • 16. Investigation of comet assays under conditions mimicking ocular instillation administration in a three-dimensional reconstructed human corneal epithelial model.
    Tahara H, Sadamoto K, Yamagiwa Y, Nemoto S, Kurata M.
    Cutan Ocul Toxicol; 2019 Dec 30; 38(4):375-383. PubMed ID: 31223032
    [Abstract] [Full Text] [Related]

  • 17. Single-cell gel electrophoresis assays with human-derived hepatoma (Hep G2) cells.
    Uhl M, Helma C, Knasmüller S.
    Mutat Res; 1999 May 17; 441(2):215-24. PubMed ID: 10333535
    [Abstract] [Full Text] [Related]

  • 18. Insensitivity of the in vitro cytokinesis-block micronucleus assay with human lymphocytes for the detection of DNA damage present at the start of the cell culture.
    Speit G, Linsenmeyer R, Schütz P, Kuehner S.
    Mutagenesis; 2012 Nov 17; 27(6):743-7. PubMed ID: 22869611
    [Abstract] [Full Text] [Related]

  • 19. Evaluation of the single cell gel electrophoresis assay with human hepatoma (Hep G2) cells.
    Uhl M, Helma C, Knasmüller S.
    Mutat Res; 2000 Jul 10; 468(2):213-25. PubMed ID: 10882898
    [Abstract] [Full Text] [Related]

  • 20. Genotoxic effects of dietary and lifestyle related carcinogens in human derived hepatoma (HepG2, Hep3B) cells.
    Majer BJ, Mersch-Sundermann V, Darroudi F, Laky B, de Wit K, Knasmüller S.
    Mutat Res; 2004 Jul 13; 551(1-2):153-66. PubMed ID: 15225590
    [Abstract] [Full Text] [Related]


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