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257 related items for PubMed ID: 12694869

  • 1. Cellular bases of the antitumor activity of a 7-substituted camptothecin in hormone-refractory human prostate carcinoma models.
    Zuco V, Supino R, De Cesare M, Carenini N, Perego P, Gatti L, Pratesi G, Pisano C, Martinelli R, Bucci F, Zanier R, Carminati P, Zunino F.
    Biochem Pharmacol; 2003 Apr 15; 65(8):1281-94. PubMed ID: 12694869
    [Abstract] [Full Text] [Related]

  • 2. Pattern of antitumor activity of a novel camptothecin, ST1481, in a large panel of human tumor xenografts.
    Pratesi G, De Cesare M, Carenini N, Perego P, Righetti SC, Cucco C, Merlini L, Pisano C, Penco S, Carminati P, Vesci L, Zunino F.
    Clin Cancer Res; 2002 Dec 15; 8(12):3904-9. PubMed ID: 12473606
    [Abstract] [Full Text] [Related]

  • 3. Potent antitumor activity and improved pharmacological profile of ST1481, a novel 7-substituted camptothecin.
    De Cesare M, Pratesi G, Perego P, Carenini N, Tinelli S, Merlini L, Penco S, Pisano C, Bucci F, Vesci L, Pace S, Capocasa F, Carminati P, Zunino F.
    Cancer Res; 2001 Oct 01; 61(19):7189-95. PubMed ID: 11585754
    [Abstract] [Full Text] [Related]

  • 4. Cell cycle checkpoint efficiency and cellular response to paclitaxel in prostate cancer cells.
    Lanzi C, Cassinelli G, Cuccuru G, Supino R, Zuco V, Ferlini C, Scambia G, Zunino F.
    Prostate; 2001 Sep 15; 48(4):254-64. PubMed ID: 11536305
    [Abstract] [Full Text] [Related]

  • 5. Docetaxel-ST1481 sequence exerts a potent cytotoxic activity on hormone-resistant prostate cancer cells by reducing drug resistance-related gene expression.
    Fabbri F, Brigliadori G, Carloni S, Ulivi P, Tesei A, Silvestrini R, Amadori D, Zoli W.
    Prostate; 2010 Feb 01; 70(2):219-27. PubMed ID: 19790230
    [Abstract] [Full Text] [Related]

  • 6. Apoptosis as a determinant of tumor sensitivity to topotecan in human ovarian tumors: preclinical in vitro/in vivo studies.
    Caserini C, Pratesi G, Tortoreto M, Bedogné B, Carenini N, Supino R, Perego P, Righetti SC, Zunino F.
    Clin Cancer Res; 1997 Jun 01; 3(6):955-61. PubMed ID: 9815771
    [Abstract] [Full Text] [Related]

  • 7. Cellular basis of antiproliferative and antitumor activity of the novel camptothecin derivative, gimatecan, in bladder carcinoma models.
    Ulivi P, Zoli W, Fabbri F, Brigliadori G, Ricotti L, Tesei A, Rosetti M, De Cesare M, Beretta GL, Corna E, Supino R, Zunino F.
    Neoplasia; 2005 Feb 01; 7(2):152-61. PubMed ID: 15802020
    [Abstract] [Full Text] [Related]

  • 8. Cellular bases of the antitumor activity of the novel taxane IDN 5109 (BAY59-8862) on hormone-refractory prostate cancer.
    Cassinelli G, Lanzi C, Supino R, Pratesi G, Zuco V, Laccabue D, Cuccuru G, Bombardelli E, Zunino F.
    Clin Cancer Res; 2002 Aug 01; 8(8):2647-54. PubMed ID: 12171897
    [Abstract] [Full Text] [Related]

  • 9. ATM- and ATR-mediated response to DNA damage induced by a novel camptothecin, ST1968.
    Zuco V, Benedetti V, Zunino F.
    Cancer Lett; 2010 Jun 28; 292(2):186-96. PubMed ID: 20042274
    [Abstract] [Full Text] [Related]

  • 10. A novel 9-aza-anthrapyrazole effective against human prostatic carcinoma xenografts.
    Supino R, Polizzi D, Pavesi R, Pratesi G, Guano F, Capranico G, Palumbo M, Sissi C, Richter S, Beggiolin G, Menta E, Pezzoni G, Spinelli S, Torriani D, Carenini N, Dal Bo L, Facchinetti F, Tortoreto M, Zunino F.
    Oncology; 2001 Jun 28; 61(3):234-42. PubMed ID: 11574780
    [Abstract] [Full Text] [Related]

  • 11. Subcellular localization of the camptothecin analogues, topotecan and gimatecan.
    Croce AC, Bottiroli G, Supino R, Favini E, Zuco V, Zunino F.
    Biochem Pharmacol; 2004 Mar 15; 67(6):1035-45. PubMed ID: 15006540
    [Abstract] [Full Text] [Related]

  • 12. The novel lipophilic camptothecin analogue gimatecan is very active in vitro in human neuroblastoma: a comparative study with SN38 and topotecan.
    Di Francesco AM, Riccardi A, Barone G, Rutella S, Meco D, Frapolli R, Zucchetti M, D'Incalci M, Pisano C, Carminati P, Riccardi R.
    Biochem Pharmacol; 2005 Oct 15; 70(8):1125-36. PubMed ID: 16139802
    [Abstract] [Full Text] [Related]

  • 13. A novel oral camptothecin analog, gimatecan, exhibits superior antitumor efficacy than irinotecan toward esophageal squamous cell carcinoma in vitro and in vivo.
    Zou J, Li S, Chen Z, Lu Z, Gao J, Zou J, Lin X, Li Y, Zhang C, Shen L.
    Cell Death Dis; 2018 May 31; 9(6):661. PubMed ID: 29855512
    [Abstract] [Full Text] [Related]

  • 14. Chimmitecan, a novel 9-substituted camptothecin, with improved anticancer pharmacologic profiles in vitro and in vivo.
    Huang M, Gao H, Chen Y, Zhu H, Cai Y, Zhang X, Miao Z, Jiang H, Zhang J, Shen H, Lin L, Lu W, Ding J.
    Clin Cancer Res; 2007 Feb 15; 13(4):1298-307. PubMed ID: 17287296
    [Abstract] [Full Text] [Related]

  • 15. Induction of p53-dependent and p53-independent cellular responses by topoisomerase 1 inhibitors.
    McDonald AC, Brown R.
    Br J Cancer; 1998 Sep 15; 78(6):745-51. PubMed ID: 9743293
    [Abstract] [Full Text] [Related]

  • 16. Anti-proliferative effects of evodiamine on human prostate cancer cell lines DU145 and PC3.
    Kan SF, Yu CH, Pu HF, Hsu JM, Chen MJ, Wang PS.
    J Cell Biochem; 2007 May 01; 101(1):44-56. PubMed ID: 17340628
    [Abstract] [Full Text] [Related]

  • 17. Implications of p53 in growth arrest and apoptosis on combined treatment of human Mammary epithelial cells with topotecan and UCN-01.
    Redkar A, Mixter P, Daoud SS.
    J Exp Ther Oncol; 2004 Oct 01; 4(3):213-22. PubMed ID: 15724841
    [Abstract] [Full Text] [Related]

  • 18. Novel 7-substituted camptothecins with potent antitumor activity.
    Dallavalle S, Delsoldato T, Ferrari A, Merlini L, Penco S, Carenini N, Perego P, De Cesare M, Pratesi G, Zunino F.
    J Med Chem; 2000 Oct 19; 43(21):3963-9. PubMed ID: 11052801
    [Abstract] [Full Text] [Related]

  • 19. Characterisation of a human small-cell lung cancer cell line resistant to the DNA topoisomerase I-directed drug topotecan.
    Sorensen M, Sehested M, Jensen PB.
    Br J Cancer; 1995 Aug 19; 72(2):399-404. PubMed ID: 7640225
    [Abstract] [Full Text] [Related]

  • 20. A novel small molecule hybrid of vorinostat and DACA displays anticancer activity against human hormone-refractory metastatic prostate cancer through dual inhibition of histone deacetylase and topoisomerase I.
    Yu CC, Pan SL, Chao SW, Liu SP, Hsu JL, Yang YC, Li TK, Huang WJ, Guh JH.
    Biochem Pharmacol; 2014 Aug 01; 90(3):320-30. PubMed ID: 24915421
    [Abstract] [Full Text] [Related]

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