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Journal Abstract Search

342 related items for PubMed ID: 12695338

  • 1. Regulation of drug transporter gene expression by nuclear receptors.
    Staudinger JL, Madan A, Carol KM, Parkinson A.
    Drug Metab Dispos; 2003 May; 31(5):523-7. PubMed ID: 12695338
    [Abstract] [Full Text] [Related]

  • 2. Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor.
    Staudinger J, Liu Y, Madan A, Habeebu S, Klaassen CD.
    Drug Metab Dispos; 2001 Nov; 29(11):1467-72. PubMed ID: 11602523
    [Abstract] [Full Text] [Related]

  • 3. Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity.
    Guo GL, Lambert G, Negishi M, Ward JM, Brewer HB, Kliewer SA, Gonzalez FJ, Sinal CJ.
    J Biol Chem; 2003 Nov 14; 278(46):45062-71. PubMed ID: 12923173
    [Abstract] [Full Text] [Related]

  • 4. Induction of cytochrome P450 3A by paclitaxel in mice: pivotal role of the nuclear xenobiotic receptor, pregnane X receptor.
    Nallani SC, Goodwin B, Maglich JM, Buckley DJ, Buckley AR, Desai PB.
    Drug Metab Dispos; 2003 May 14; 31(5):681-4. PubMed ID: 12695359
    [Abstract] [Full Text] [Related]

  • 5. CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11.
    Anakk S, Kalsotra A, Kikuta Y, Huang W, Zhang J, Staudinger JL, Moore DD, Strobel HW.
    Pharmacogenomics J; 2004 May 14; 4(2):91-101. PubMed ID: 14770174
    [Abstract] [Full Text] [Related]

  • 6. The involvement of the pregnane X receptor in hepatic gene regulation during inflammation in mice.
    Teng S, Piquette-Miller M.
    J Pharmacol Exp Ther; 2005 Feb 14; 312(2):841-8. PubMed ID: 15456840
    [Abstract] [Full Text] [Related]

  • 7. A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression.
    Wang H, Faucette S, Sueyoshi T, Moore R, Ferguson S, Negishi M, LeCluyse EL.
    J Biol Chem; 2003 Apr 18; 278(16):14146-52. PubMed ID: 12571232
    [Abstract] [Full Text] [Related]

  • 8. Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response.
    Wei P, Zhang J, Dowhan DH, Han Y, Moore DD.
    Pharmacogenomics J; 2002 Apr 18; 2(2):117-26. PubMed ID: 12049174
    [Abstract] [Full Text] [Related]

  • 9. Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.
    Maglich JM, Stoltz CM, Goodwin B, Hawkins-Brown D, Moore JT, Kliewer SA.
    Mol Pharmacol; 2002 Sep 18; 62(3):638-46. PubMed ID: 12181440
    [Abstract] [Full Text] [Related]

  • 10. Human constitutive androstane receptor (CAR) and pregnane X receptor (PXR) support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogens phenobarbital and chlordane in vivo.
    Ross J, Plummer SM, Rode A, Scheer N, Bower CC, Vogel O, Henderson CJ, Wolf CR, Elcombe CR.
    Toxicol Sci; 2010 Aug 18; 116(2):452-66. PubMed ID: 20403969
    [Abstract] [Full Text] [Related]

  • 11. Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes.
    Sahi J, Shord SS, Lindley C, Ferguson S, LeCluyse EL.
    J Biochem Mol Toxicol; 2009 Aug 18; 23(1):43-58. PubMed ID: 19202563
    [Abstract] [Full Text] [Related]

  • 12. Transcriptional regulation of cytochrome p450 2B genes by nuclear receptors.
    Wang H, Negishi M.
    Curr Drug Metab; 2003 Dec 18; 4(6):515-25. PubMed ID: 14683479
    [Abstract] [Full Text] [Related]

  • 13. Enhanced induction of cytochrome P450 enzymes and CAR binding in TNF (p55(-/-)/p75(-/-)) double receptor knockout mice following phenobarbital treatment.
    Van Ess PJ, Mattson MP, Blouin RA.
    J Pharmacol Exp Ther; 2002 Mar 18; 300(3):824-30. PubMed ID: 11861787
    [Abstract] [Full Text] [Related]

  • 14. Constitutive androstane receptor and pregnane X receptor gene expression in human liver: interindividual variability and correlation with CYP2B6 mRNA levels.
    Chang TK, Bandiera SM, Chen J.
    Drug Metab Dispos; 2003 Jan 18; 31(1):7-10. PubMed ID: 12485946
    [Abstract] [Full Text] [Related]

  • 15. The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity.
    Zhang J, Huang W, Qatanani M, Evans RM, Moore DD.
    J Biol Chem; 2004 Nov 19; 279(47):49517-22. PubMed ID: 15358766
    [Abstract] [Full Text] [Related]

  • 16. Kupffer cells and reactive oxygen species partially mediate lipopolysaccharide-induced downregulation of nuclear receptor pregnane x receptor and its target gene CYP3a in mouse liver.
    Xu DX, Wei W, Sun MF, Wu CY, Wang JP, Wei LZ, Zhou CF.
    Free Radic Biol Med; 2004 Jul 01; 37(1):10-22. PubMed ID: 15183191
    [Abstract] [Full Text] [Related]

  • 17. Induction of CYP3A expression by dehydroepiandrosterone: involvement of the pregnane X receptor.
    Ripp SL, Fitzpatrick JL, Peters JM, Prough RA.
    Drug Metab Dispos; 2002 May 01; 30(5):570-5. PubMed ID: 11950789
    [Abstract] [Full Text] [Related]

  • 18. Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor.
    Faucette SR, Sueyoshi T, Smith CM, Negishi M, Lecluyse EL, Wang H.
    J Pharmacol Exp Ther; 2006 Jun 01; 317(3):1200-9. PubMed ID: 16513849
    [Abstract] [Full Text] [Related]

  • 19. Endocrine disruptors induce cytochrome P450 by affecting transcriptional regulation via pregnane X receptor.
    Mikamo E, Harada S, Nishikawa J, Nishihara T.
    Toxicol Appl Pharmacol; 2003 Nov 15; 193(1):66-72. PubMed ID: 14613717
    [Abstract] [Full Text] [Related]

  • 20. Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice.
    Saini SP, Mu Y, Gong H, Toma D, Uppal H, Ren S, Li S, Poloyac SM, Xie W.
    Hepatology; 2005 Mar 15; 41(3):497-505. PubMed ID: 15726644
    [Abstract] [Full Text] [Related]

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