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Journal Abstract Search

232 related items for PubMed ID: 12697808

  • 1. Bile acid regulation of C/EBPbeta, CREB, and c-Jun function, via the extracellular signal-regulated kinase and c-Jun NH2-terminal kinase pathways, modulates the apoptotic response of hepatocytes.
    Qiao L, Han SI, Fang Y, Park JS, Gupta S, Gilfor D, Amorino G, Valerie K, Sealy L, Engelhardt JF, Grant S, Hylemon PB, Dent P.
    Mol Cell Biol; 2003 May; 23(9):3052-66. PubMed ID: 12697808
    [Abstract] [Full Text] [Related]

  • 2. Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis.
    Qiao L, Studer E, Leach K, McKinstry R, Gupta S, Decker R, Kukreja R, Valerie K, Nagarkatti P, El Deiry W, Molkentin J, Schmidt-Ullrich R, Fisher PB, Grant S, Hylemon PB, Dent P.
    Mol Biol Cell; 2001 Sep; 12(9):2629-45. PubMed ID: 11553704
    [Abstract] [Full Text] [Related]

  • 3. Deoxycholic acid activates the c-Jun N-terminal kinase pathway via FAS receptor activation in primary hepatocytes. Role of acidic sphingomyelinase-mediated ceramide generation in FAS receptor activation.
    Gupta S, Natarajan R, Payne SG, Studer EJ, Spiegel S, Dent P, Hylemon PB.
    J Biol Chem; 2004 Feb 13; 279(7):5821-8. PubMed ID: 14660582
    [Abstract] [Full Text] [Related]

  • 4. 17-Allylamino-17-demethoxygeldanamycin enhances the lethality of deoxycholic acid in primary rodent hepatocytes and established cell lines.
    Mitchell C, Park MA, Zhang G, Han SI, Harada H, Franklin RA, Yacoub A, Li PL, Hylemon PB, Grant S, Dent P.
    Mol Cancer Ther; 2007 Feb 13; 6(2):618-32. PubMed ID: 17308059
    [Abstract] [Full Text] [Related]

  • 5. Bile acid regulates MUC2 transcription in colon cancer cells via positive EGFR/PKC/Ras/ERK/CREB, PI3K/Akt/IkappaB/NF-kappaB and p38/MSK1/CREB pathways and negative JNK/c-Jun/AP-1 pathway.
    Lee HY, Crawley S, Hokari R, Kwon S, Kim YS.
    Int J Oncol; 2010 Apr 13; 36(4):941-53. PubMed ID: 20198339
    [Abstract] [Full Text] [Related]

  • 6. Cyclin kinase inhibitor p21 potentiates bile acid-induced apoptosis in hepatocytes that is dependent on p53.
    Qiao L, McKinstry R, Gupta S, Gilfor D, Windle JJ, Hylemon PB, Grant S, Fisher PB, Dent P.
    Hepatology; 2002 Jul 13; 36(1):39-48. PubMed ID: 12085347
    [Abstract] [Full Text] [Related]

  • 7. Multiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signaling.
    Zhang G, Park MA, Mitchell C, Walker T, Hamed H, Studer E, Graf M, Rahmani M, Gupta S, Hylemon PB, Fisher PB, Grant S, Dent P.
    J Biol Chem; 2008 Sep 05; 283(36):24343-58. PubMed ID: 18614532
    [Abstract] [Full Text] [Related]

  • 8. Activation of extracellular signal-regulated kinase and c-Jun-NH(2)-terminal kinase but not p38 mitogen-activated protein kinases is required for RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells.
    Yu W, Liao QY, Hantash FM, Sanders BG, Kline K.
    Cancer Res; 2001 Sep 01; 61(17):6569-76. PubMed ID: 11522656
    [Abstract] [Full Text] [Related]

  • 9. Bile acid-induced activation of activator protein-1 requires both extracellular signal-regulated kinase and protein kinase C signaling.
    Qiao D, Chen W, Stratagoules ED, Martinez JD.
    J Biol Chem; 2000 May 19; 275(20):15090-8. PubMed ID: 10748108
    [Abstract] [Full Text] [Related]

  • 10. Hepatocyte resistance to oxidative stress is dependent on protein kinase C-mediated down-regulation of c-Jun/AP-1.
    Wang Y, Schattenberg JM, Rigoli RM, Storz P, Czaja MJ.
    J Biol Chem; 2004 Jul 23; 279(30):31089-97. PubMed ID: 15145937
    [Abstract] [Full Text] [Related]

  • 11. Bile acids induce mitochondrial ROS, which promote activation of receptor tyrosine kinases and signaling pathways in rat hepatocytes.
    Fang Y, Han SI, Mitchell C, Gupta S, Studer E, Grant S, Hylemon PB, Dent P.
    Hepatology; 2004 Oct 23; 40(4):961-71. PubMed ID: 15382121
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes.
    Qiao L, Yacoub A, Studer E, Gupta S, Pei XY, Grant S, Hylemon PB, Dent P.
    Hepatology; 2002 Apr 23; 35(4):779-89. PubMed ID: 11915023
    [Abstract] [Full Text] [Related]

  • 13. Anti-apoptotic effect of quercetin: intervention in the JNK- and ERK-mediated apoptotic pathways.
    Ishikawa Y, Kitamura M.
    Kidney Int; 2000 Sep 23; 58(3):1078-87. PubMed ID: 10972672
    [Abstract] [Full Text] [Related]

  • 14. Induction of cyclooxygenase-2 by bovine type I collagen in macrophages via C/EBP and CREB activation by multiple cell signaling pathways.
    Cho MK, Cho YH, Lee GH, Kim SG.
    Biochem Pharmacol; 2004 Jun 15; 67(12):2239-50. PubMed ID: 15163555
    [Abstract] [Full Text] [Related]

  • 15. c-Jun N-terminal kinase 1/c-Jun activation of the p53/microRNA 34a/sirtuin 1 pathway contributes to apoptosis induced by deoxycholic acid in rat liver.
    Ferreira DM, Afonso MB, Rodrigues PM, Simão AL, Pereira DM, Borralho PM, Rodrigues CM, Castro RE.
    Mol Cell Biol; 2014 Mar 15; 34(6):1100-20. PubMed ID: 24421392
    [Abstract] [Full Text] [Related]

  • 16. Potentiation of lipopolysaccharide-inducible cyclooxygenase 2 expression by C2-ceramide via c-Jun N-terminal kinase-mediated activation of CCAAT/enhancer binding protein beta in macrophages.
    Cho YH, Lee CH, Kim SG.
    Mol Pharmacol; 2003 Mar 15; 63(3):512-23. PubMed ID: 12606757
    [Abstract] [Full Text] [Related]

  • 17. Cytokines increase CRE binding but decrease CRE-mediated reporter activity in rat hepatocytes by increasing c-Jun.
    Zhang B, Liu S, Perpetua MD, Walker WH, Harbrecht BG.
    Hepatology; 2004 May 15; 39(5):1343-52. PubMed ID: 15122763
    [Abstract] [Full Text] [Related]

  • 18. In cardiomyocyte hypoxia, insulin-like growth factor-I-induced antiapoptotic signaling requires phosphatidylinositol-3-OH-kinase-dependent and mitogen-activated protein kinase-dependent activation of the transcription factor cAMP response element-binding protein.
    Mehrhof FB, Müller FU, Bergmann MW, Li P, Wang Y, Schmitz W, Dietz R, von Harsdorf R.
    Circulation; 2001 Oct 23; 104(17):2088-94. PubMed ID: 11673351
    [Abstract] [Full Text] [Related]

  • 19. Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway.
    Gupta S, Stravitz RT, Dent P, Hylemon PB.
    J Biol Chem; 2001 May 11; 276(19):15816-22. PubMed ID: 11278771
    [Abstract] [Full Text] [Related]

  • 20. Activation and role of mitogen-activated protein kinases in deoxycholic acid-induced apoptosis.
    Qiao D, Stratagouleas ED, Martinez JD.
    Carcinogenesis; 2001 Jan 11; 22(1):35-41. PubMed ID: 11159738
    [Abstract] [Full Text] [Related]

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