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Journal Abstract Search

202 related items for PubMed ID: 12699385

  • 1. Synthesis, anticancer activity, and inhibition of tubulin polymerization by conformationally restricted analogues of lavendustin A.
    Mu F, Hamel E, Lee DJ, Pryor DE, Cushman M.
    J Med Chem; 2003 Apr 24; 46(9):1670-82. PubMed ID: 12699385
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and investigation of conformationally restricted analogues of lavendustin A as cytotoxic inhibitors of tubulin polymerization.
    Mu F, Lee DJ, Pryor DE, Hamel E, Cushman M.
    J Med Chem; 2002 Oct 10; 45(21):4774-85. PubMed ID: 12361405
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis, and biological evaluation of a series of lavendustin A analogues that inhibit EGFR and Syk tyrosine kinases, as well as tubulin polymerization.
    Mu F, Coffing SL, Riese DJ, Geahlen RL, Verdier-Pinard P, Hamel TE, Johnson J, Cushman M.
    J Med Chem; 2001 Feb 01; 44(3):441-52. PubMed ID: 11462983
    [Abstract] [Full Text] [Related]

  • 4. Antineoplastic agents. 445. Synthesis and evaluation of structural modifications of (Z)- and (E)-combretastatin A-41.
    Pettit GR, Rhodes MR, Herald DL, Hamel E, Schmidt JM, Pettit RK.
    J Med Chem; 2005 Jun 16; 48(12):4087-99. PubMed ID: 15943482
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and evaluation of analogues of (Z)-1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene as potential cytotoxic and antimitotic agents.
    Cushman M, Nagarathnam D, Gopal D, He HM, Lin CM, Hamel E.
    J Med Chem; 1992 Jun 12; 35(12):2293-306. PubMed ID: 1613753
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and biological activity of fluorinated combretastatin analogues.
    Alloatti D, Giannini G, Cabri W, Lustrati I, Marzi M, Ciacci A, Gallo G, Tinti MO, Marcellini M, Riccioni T, Guglielmi MB, Carminati P, Pisano C.
    J Med Chem; 2008 May 08; 51(9):2708-21. PubMed ID: 18396857
    [Abstract] [Full Text] [Related]

  • 7. 1,5-Disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin.
    Odlo K, Hentzen J, dit Chabert JF, Ducki S, Gani OA, Sylte I, Skrede M, Flørenes VA, Hansen TV.
    Bioorg Med Chem; 2008 May 01; 16(9):4829-38. PubMed ID: 18396050
    [Abstract] [Full Text] [Related]

  • 8. Lead identification of conformationally restricted β-lactam type combretastatin analogues: synthesis, antiproliferative activity and tubulin targeting effects.
    Carr M, Greene LM, Knox AJ, Lloyd DG, Zisterer DM, Meegan MJ.
    Eur J Med Chem; 2010 Dec 01; 45(12):5752-66. PubMed ID: 20933304
    [Abstract] [Full Text] [Related]

  • 9. Effects of altering the electronics of 2-methoxyestradiol on cell proliferation, on cytotoxicity in human cancer cell cultures, and on tubulin polymerization.
    Edsall AB, Mohanakrishnan AK, Yang D, Fanwick PE, Hamel E, Hanson AD, Agoston GE, Cushman M.
    J Med Chem; 2004 Oct 07; 47(21):5126-39. PubMed ID: 15456256
    [Abstract] [Full Text] [Related]

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  • 11. 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
    Chang JY, Yang MF, Chang CY, Chen CM, Kuo CC, Liou JP.
    J Med Chem; 2006 Oct 19; 49(21):6412-5. PubMed ID: 17034147
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  • 14. Further naphthylcombretastatins. An investigation on the role of the naphthalene moiety.
    Maya AB, Pérez-Melero C, Mateo C, Alonso D, Fernández JL, Gajate C, Mollinedo F, Peláez R, Caballero E, Medarde M.
    J Med Chem; 2005 Jan 27; 48(2):556-68. PubMed ID: 15658869
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  • 16. Photoswitchable anticancer activity via trans-cis isomerization of a combretastatin A-4 analog.
    Sheldon JE, Dcona MM, Lyons CE, Hackett JC, Hartman MC.
    Org Biomol Chem; 2016 Jan 07; 14(1):40-9. PubMed ID: 26503632
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  • 18. Combretastatin dinitrogen-substituted stilbene analogues as tubulin-binding and vascular-disrupting agents.
    Siles R, Ackley JF, Hadimani MB, Hall JJ, Mugabe BE, Guddneppanavar R, Monk KA, Chapuis JC, Pettit GR, Chaplin DJ, Edvardsen K, Trawick ML, Garner CM, Pinney KG.
    J Nat Prod; 2008 Mar 07; 71(3):313-20. PubMed ID: 18303849
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  • 19. Synthesis and biological evaluation of 4-arylcoumarin analogues of combretastatins.
    Bailly C, Bal C, Barbier P, Combes S, Finet JP, Hildebrand MP, Peyrot V, Wattez N.
    J Med Chem; 2003 Dec 04; 46(25):5437-44. PubMed ID: 14640552
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