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202 related items for PubMed ID: 12699385
21. Antineoplastic agents. 410. Asymmetric hydroxylation of trans-combretastatin A-4. Pettit GR, Toki BE, Herald DL, Boyd MR, Hamel E, Pettit RK, Chapuis JC. J Med Chem; 1999 Apr 22; 42(8):1459-65. PubMed ID: 10212132 [Abstract] [Full Text] [Related]
22. The effect of exchanging various substituents at the 2-position of 2-methoxyestradiol on cytotoxicity in human cancer cell cultures and inhibition of tubulin polymerization. Cushman M, Mohanakrishnan AK, Hollingshead M, Hamel E. J Med Chem; 2002 Oct 10; 45(21):4748-54. PubMed ID: 12361402 [Abstract] [Full Text] [Related]
23. Methoxy-substituted 3-formyl-2-phenylindoles inhibit tubulin polymerization. Gastpar R, Goldbrunner M, Marko D, von Angerer E. J Med Chem; 1998 Dec 03; 41(25):4965-72. PubMed ID: 9836614 [Abstract] [Full Text] [Related]
24. Arylthioindoles, potent inhibitors of tubulin polymerization. De Martino G, La Regina G, Coluccia A, Edler MC, Barbera MC, Brancale A, Wilcox E, Hamel E, Artico M, Silvestri R. J Med Chem; 2004 Dec 02; 47(25):6120-3. PubMed ID: 15566282 [Abstract] [Full Text] [Related]
25. Synthesis and anticancer activity of lavendustin A derivatives containing arylethenylchromone substituents. Lee KY, Nam DH, Moon CS, Seo SH, Lee JY, Lee YS. Eur J Med Chem; 2006 Aug 02; 41(8):991-6. PubMed ID: 16762460 [Abstract] [Full Text] [Related]
26. A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation. Naret T, Bignon J, Bernadat G, Benchekroun M, Levaique H, Lenoir C, Dubois J, Pruvost A, Saller F, Borgel D, Manoury B, Leblais V, Darrigrand R, Apcher S, Brion JD, Schmitt E, Leroux FR, Alami M, Hamze A. Eur J Med Chem; 2018 Jan 01; 143():473-490. PubMed ID: 29202409 [Abstract] [Full Text] [Related]
27. Synthesis of alkoxy-substituted diaryl compounds and correlation of ring separation with inhibition of tubulin polymerization: differential enhancement of inhibitory effects under suboptimal polymerization reaction conditions. Getahun Z, Jurd L, Chu PS, Lin CM, Hamel E. J Med Chem; 1992 Mar 20; 35(6):1058-67. PubMed ID: 1552500 [Abstract] [Full Text] [Related]
28. Synthesis and structure-activity relationships of constrained heterocyclic analogues of combretastatin A4. Arthuis M, Pontikis R, Chabot GG, Seguin J, Quentin L, Bourg S, Morin-Allory L, Florent JC. ChemMedChem; 2011 Sep 05; 6(9):1693-705. PubMed ID: 21732536 [Abstract] [Full Text] [Related]
29. Synthesis and cytotoxic evaluation of combretafurans, potential scaffolds for dual-action antitumoral agents. Pirali T, Busacca S, Beltrami L, Imovilli D, Pagliai F, Miglio G, Massarotti A, Verotta L, Tron GC, Sorba G, Genazzani AA. J Med Chem; 2006 Aug 24; 49(17):5372-6. PubMed ID: 16913727 [Abstract] [Full Text] [Related]
30. Antineoplastic agents. 487. Synthesis and biological evaluation of the antineoplastic agent 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene and derived amino acid amides. Pettit GR, Anderson CR, Herald DL, Jung MK, Lee DJ, Hamel E, Pettit RK. J Med Chem; 2003 Feb 13; 46(4):525-31. PubMed ID: 12570374 [Abstract] [Full Text] [Related]
31. Synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agents. Roberti M, Pizzirani D, Simoni D, Rondanin R, Baruchello R, Bonora C, Buscemi F, Grimaudo S, Tolomeo M. J Med Chem; 2003 Jul 31; 46(16):3546-54. PubMed ID: 12877593 [Abstract] [Full Text] [Related]
32. 6-Alkylamino- and 2,3-dihydro-3'-methoxy-2-phenyl-4-quinazolinones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization. Hour MJ, Huang LJ, Kuo SC, Xia Y, Bastow K, Nakanishi Y, Hamel E, Lee KH. J Med Chem; 2000 Nov 16; 43(23):4479-87. PubMed ID: 11087572 [Abstract] [Full Text] [Related]
33. Novel hybrid nocodazole analogues as tubulin polymerization inhibitors and their antiproliferative activity. Kale SS, Jedhe GS, Meshram SN, Santra MK, Hamel E, Sanjayan GJ. Bioorg Med Chem Lett; 2015 May 01; 25(9):1982-5. PubMed ID: 25817588 [Abstract] [Full Text] [Related]
34. Regioselective Suzuki coupling of dihaloheteroaromatic compounds as a rapid strategy to synthesize potent rigid combretastatin analogues. Theeramunkong S, Caldarelli A, Massarotti A, Aprile S, Caprioglio D, Zaninetti R, Teruggi A, Pirali T, Grosa G, Tron GC, Genazzani AA. J Med Chem; 2011 Jul 28; 54(14):4977-86. PubMed ID: 21696175 [Abstract] [Full Text] [Related]
35. Imidazolone-amide bridges and their effects on tubulin polymerization in cis-locked vinylogous combretastatin-A4 analogues: synthesis and biological evaluation. Li YW, Liu J, Liu N, Shi D, Zhou XT, Lv JG, Zhu J, Zheng CH, Zhou YJ. Bioorg Med Chem; 2011 Jun 01; 19(11):3579-84. PubMed ID: 21536450 [Abstract] [Full Text] [Related]
36. Synthesis, biological evaluation and molecular docking studies of resveratrol derivatives possessing curcumin moiety as potent antitubulin agents. Ruan BF, Lu X, Li TT, Tang JF, Wei Y, Wang XL, Zheng SL, Yao RS, Zhu HL. Bioorg Med Chem; 2012 Jan 15; 20(2):1113-21. PubMed ID: 22189271 [Abstract] [Full Text] [Related]
37. Synthesis and antiproliferative effects of 5,6-disubstituted Pyridazin-3(2H)-ones designed as conformationally constrained combretastatin A-4 Analogues. Elagawany M, Schmitt M, Ghiaty A, El-Etrawy ASh, Ibrahim MA, Bihel F, Sbardelotto AB, Pessoa C, Nguyen TL, Hamel E, Bourguignon JJ. Anticancer Agents Med Chem; 2013 Sep 15; 13(7):1133-40. PubMed ID: 23574386 [Abstract] [Full Text] [Related]
38. Conformationally restricted macrocyclic analogues of combretastatins. Mateo C, Alvarez R, Pérez-Melero C, Peláez R, Medarde M. Bioorg Med Chem Lett; 2007 Nov 15; 17(22):6316-20. PubMed ID: 17889536 [Abstract] [Full Text] [Related]
39. Exploring the size adaptability of the B ring binding zone of the colchicine site of tubulin with para-nitrogen substituted isocombretastatins. Jiménez C, Ellahioui Y, Álvarez R, Aramburu L, Riesco A, González M, Vicente A, Dahdouh A, Ibn Mansour A, Jiménez C, Martín D, Sarmiento RG, Medarde M, Caballero E, Peláez R. Eur J Med Chem; 2015 Jul 15; 100():210-22. PubMed ID: 26092446 [Abstract] [Full Text] [Related]
40. Synthesis and biological activity of mustard derivatives of combretastatins. Coggiola B, Pagliai F, Allegrone G, Genazzani AA, Tron GC. Bioorg Med Chem Lett; 2005 Aug 01; 15(15):3551-4. PubMed ID: 15963722 [Abstract] [Full Text] [Related] Page: [Previous] [Next] [New Search]